Research Infrastructure Programs
Open Opportunities (15)
Live Grants.gov opportunities funded under this program — you can apply now.
- Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) Deadline: Jul 1, 2026 · up to $5M
- Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed) Deadline: Jul 1, 2026 · up to $400K
- Modern Equipment for Shared-use Biomedical Research Facilities: Advancing Research-Related Operations (S15 Clinical Trial Not Allowed) Deadline: Sep 25, 2026 · up to $350K
- Utilizing Equipment to Study Environmental Extrinsic Factors and Enhance Rigor and Reproducibility of Animal Research (R24, Clinical Trials Not-Allowed) Deadline: Sep 25, 2026
- Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed) Deadline: Sep 25, 2026
- Integrated Specific Pathogen Free Research Models and Human New Approach Methodologies to Advance HIV/AIDS Research (U42 Clinical Trial Not Allowed) Deadline: Jan 25, 2027 · up to $2.7M
- Research Resource for a National Swine Resource and Research Center (U42 Clinical Trial Not Allowed) Deadline: Jan 25, 2027 · up to $1M
- National Biomedical Research Centers (P50 Clinical Trial Optional) Deadline: Jan 25, 2027 · up to $11.4M
- High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) Deadline: Jun 1, 2027
- Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed) Deadline: Jun 1, 2027
- Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) Deadline: Jun 1, 2027
- Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed) Deadline: Jan 7, 2028 · up to $200K
- INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed) Deadline: Jun 15, 2028 · up to $200K
- Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed) Deadline: Sep 26, 2028
- Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed) Deadline: Sep 28, 2028
Program Funding
Annual program obligations reported to SAM.gov.
Who has received this funding
Organizations awarded under CFDA 93.351 (USAspending.gov).
- Oregon Health & Science University $189,307,929
- University Of Washington $188,853,963
- University Of California, Davis $179,413,083
- Emory University $156,271,917
- Texas Biomedical Research Institute 2 awards $155,452,387
- University Of Wisconsin System $140,230,629
- The Administrators Of Tulane Educational Fund $132,964,607
- University Of Puerto Rico Medical Sciences Campus 2 awards $75,422,031
Program Objective
The Office of Research Infrastructure Programs (ORIP) is a program office in the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) dedicated to supporting research infrastructure and related research resource programs. ORIP consists of the Division of Comparative Medicine (DCM) and the Division of Construction and Instruments (DCI).
Eligibility
Eligible Applicants
- Nonprofit Organization
- For-Profit Organization
- Federally Recognized Tribal Government
- U.S. State Government
- Municipality/Township Government
- County Government
- Small Business Person
Institutions of higher education, hospitals, and other institutions and organizations, both nonprofit and for-profit, seeking to establish, continue, or enlarge programs consistent with the objectives of the program. To be eligible for instrumentation and equipment programs, applications must be Private nonprofit institutions/organizations, Public nonprofit institutions/organizations. Applicants for NRSA must be citizens of the United States or be admitted to the United States for permanent residency. Applicants must be nominated and sponsored by a public or private nonprofit institution with staff and facilities suitable for the proposed research training. Nonprofit domestic organizations may apply for the institutional NRSA. Research Career Development: Applications may be submitted on behalf of candidates by domestic, nonfederal organizations, public or private institutions of higher education.
How to Apply
Award Procedure
The initial review of applications from eligible investigators and institutions is reviewed by committees comprised of authorities in various fields of biomedical research and science education, as appropriate. Each application is given a peer evaluation for merit, and recommendations are forwarded to the NIH Council of Councils for final review and recommendation.
Decision Timeline
- Approval: > 180 Days
- Renewal interval: > 180 Days
- Appeal: From 60 to 90 days
Program details & compliance
Description
ORIP advances the NIH mission by supporting infrastructure for innovation. This support is focused on research resources, including research models for human diseases, cutting-edge scientific instrumentation, construction and modernization of research facilities, and research training opportunities for veterinary scientists.
Mission Categories
Primary: General Health and Medical
Use of Funds
Allowed Uses
The Division of Comparative Medicine (DCM) helps meet the needs of biomedical researchers for high-quality, disease-free animals and specialized animal research facilities as well as supports the development of the biomedical workforce, specifically scientists with a background in veterinary medicine. Additionally, DCM seeks to increase small business participation in federally supported research and development as well as the private-sector commercialization of technology developed with federal support. It does this through the federal government's Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. The Division of Construction and Instruments: This Division supports programs to expand the Nation’s capacity for the conduct of biomedical research by offering grants for the acquisition of state-of the-art biomedical research instrumentation and integrated instrument systems, advanced biomedical laboratory equipment, and, when specially appropriated funds are available, grants for construction and modernization of biomedical and biobehavioral research facilities.
Reporting & Compliance
Applicable 2 CFR 200 Subparts
- Subpart B — General Provisions
- Subpart C — Pre-Federal Award Requirements
- Subpart D — Post-Federal Award Requirements
- Subpart F — Audit Requirements