Research Infrastructure Programs – Construction

Extramural Construction; Biomedical Research Facilities
CFDA 93.CN1 Active Cooperative Agreement

Program Funding

Annual program obligations reported to SAM.gov.

Latest annual funding (estimated)
$80M FY2026
$80M
FY24
$80M
FY25
$80M
FY26*
* estimated

Program Objective

The Office of Research Infrastructure Programs (ORIP), within the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) in the NIH Office of the Director, supports extramural biomedical research by strengthening the infrastructure that enables scientific discovery. ORIP advances human health by fostering the development of critical research models, biomaterials, and technologies; expanding access to state-of-the-art instrumentation and facilities; supporting education and training programs; and assisting small businesses in translating innovative technologies. Through its two divisions, the Division of Comparative Medicine (DCM) and the Division of Construction and Instruments (DCI), ORIP plays a critical role in accelerating biomedical research nationwide. DCM develops and sustains essential research models and biological resources, manages the infrastructure required for their use and distribution, and provides training to ensure investigators have reliable access to high-quality models and facilities. DCI supports shared, cost-effective access to advanced scientific instrumentation, modernizing research facilities, and providing critical equipment that enables transformative biomedical discoveries. Together, DCM and DCI strengthen U.S. competitiveness and ensure the biomedical research community has the infrastructure necessary to address emerging health challenges, prevent disease, promote health, and advance foundational science.

Eligibility

Eligible Applicants

  • Nonprofit Organization

Public/state controlled Nonprofit Institutions/Organizations; Private Institutions of Higher Education; Nonprofit other than Institutions of Higher Education Nonprofits with 501(c)(3) IRS status (Other than Institutions of Higher Education); and Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education). Foreign organizations are not eligible.

How to Apply

Award Procedure

Applications are reviewed for scientific and technical merit by a scientific review group. Each application is given a peer evaluation for merit, and recommendations are forwarded to the NIH Council of Councils for final review and recommendation.

Program details & compliance

Description

ORIP advances the NIH mission by supporting infrastructure for innovation. This support is focused on research resources, including research models for human diseases, cutting-edge scientific instrumentation, construction and modernization of research facilities, and research training opportunities for veterinary scientists.

Mission Categories

Primary: General Health and Medical

Use of Funds

Allowed Uses

New physical resources for research include basic research laboratories, clinical and support facilities, and those related to biohazard control that are integral parts of an overall effort. Proposed facilities must be part of an existing research effort or a developing research program. Facilities shall be used for research pertinent to the NIH mission for as long as needed. The usual period of Federal interest is 10 or 20 years. Funds must be used for purposes stated in the approved grant application.

Required Documentation

Applications should include a complete research program description (with staff curricula vitae), space requirements for projected program, a summary of the environmental impact of the proposed facility as detailed in Public Law 90- 190, the National Environmental Policy Act, and listing of all relevant licenses, permits, or other approvals required by State and local authorities.
This program is excluded from coverage under 2 CFR 200, Subpart E - Cost Principles.

Reporting & Compliance

Records Retention
3 years

Applicable 2 CFR 200 Subparts

  • Subpart B — General Provisions
  • Subpart C — Pre-Federal Award Requirements
  • Subpart D — Post-Federal Award Requirements
  • Subpart F — Audit Requirements

Contacts

Adrian Green — Program Analyst
3014350744
6700B Rockledge Drive, Room 4407, Bethesda, MD 20892-6931
Data from SAM.gov Federal Assistance Listings. Source published: 2026-01-28. Spec v2.0. Last synced: 2026-05-29 05:41:11.