Data and Coordinating Center (U24 Clinical trials Not Allowed)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Oct 18, 2026
Can you apply?
This grant is for research institutions and consortia to support data management, curation, and coordination infrastructure for the IGVF (Intestinal Genome to Phenotype) Consortium, a large-scale genomics research initiative funded by the NIH. Eligible applicants typically include 501(c)(3) public charities (universities, research hospitals), research centers, and established academic institutions with demonstrated capacity in bioinformatics, data coordination, and genomics research. Applicants must have institutional support, qualified personnel with expertise in data management, and infrastructure to manage large-scale genomic datasets. The scope includes data integration, quality control, portal development, and coordination services supporting IGVF research activities across multiple institutions. Clinical trials are explicitly not allowed under this funding mechanism.
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Key dates
- Apr 1, 2026 Award announced
- Apr 1, 2026 Project start
- Oct 9, 2026 Applications open
- Dec 14, 2026 Application deadline in 56 days
Program description
The National Human Genome Research Institute (NHGRI) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications for the Impact of Genomic Variation on Function (IGVF) Data and Coordinating Center (DACC). The DACC will serve as the coordinating center for the IGVF Consortium and will be responsible for expanding and further developing a broadly accessible set of resources, including a data portal and a comprehensive and searchable catalog of measured and predicted variant impacts. The DACC will also seek input on the design of the catalog from the broader research community, organize and facilitate consortium activities, and seek opportunities to work with other programs and consortia. As a member of IGVF, the DACC will work with all consortium members to maximize the consortium’s overall scientific impact and contribute to accelerating understanding of genomic variation.
This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in 2025 with an expected application due date in 2025. This NOFO will utilize the U24 activity code. Details of the planned NOFO are provided below.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (R&R) form and face page
- Project narrative describing data coordination and management services
- Detailed data management plan addressing security, archiving, and quality control
- Budget and budget justification with personnel costs clearly itemized
- Biosketches of key personnel (5-page limit per person)
- Institutional support letters and commitment documentation
- Letters of support from IGVF consortium members/partners
- Current and Pending Support statement
- Facilities and resources description detailing data infrastructure capacity
- Organization's financial documentation and indirect cost rate agreement
Program contact
- 👤 Stephanie A. Morris, Ph.D. National Human Genome Research Institute (NHGRI)
- 📧 morriss2@mail.nih.gov
- 📞 301-435-5738
Funding track record
Recent awards under CFDA 93.172 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$40,531,110
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$34,574,245
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$32,186,204
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$30,201,146
-
$30,195,606
-
$27,072,236
-
$26,495,937
-
$26,020,371
-
$24,413,854
-
$23,757,911
Top States by Funding
- CA 20 awards $335.5M
- MA 16 awards $313.7M
- WA 9 awards $140.7M
- NC 6 awards $108.5M
- NY 6 awards $104.4M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.172). How funding has trended year over year.
| 2024 | $452,727,668 | |
| 2025 | $423,878,429 | |
| 2026 est. | $9,989,158 |
FAQ
Who is eligible to apply for this IGVF Data and Coordinating Center grant?
Typically, 501(c)(3) public charities including universities, academic medical centers, and established research institutions with strong bioinformatics and data management infrastructure are eligible. Applicants must demonstrate institutional commitment and access to qualified genomics and data science personnel.
What does this funding mechanism support?
This U24 mechanism supports centralized data coordination, management, and integration services for IGVF research. Funded activities include data curation, quality assurance, database development, bioinformatics portal operations, and administrative coordination across consortium partners.
Are clinical trials eligible for this funding?
No. This solicitation explicitly excludes clinical trials. The focus is on research data infrastructure and coordination services for genomic research within the IGVF consortium framework.
What is the typical funding level and project duration?
NIH U24 grants typically provide multi-year support with varying budget levels. Contact the program officer at NIH to confirm specific funding ceiling and project period expectations for this solicitation.
How competitive is this award?
U24 awards are moderately to highly competitive. Success typically requires clear demonstration of data management capacity, a detailed plan for coordination services, strong institutional support, and alignment with IGVF research priorities.
💡 Tips for applicants
- Establish clear partnerships with IGVF consortium members early in the application process; demonstrate existing relationships and communication channels.
- Develop a detailed, realistic data management plan that addresses data intake, quality control, storage, security, and long-term curation needs.
- Highlight your institution's technical infrastructure, including server capacity, backup systems, security measures, and scalability for large genomic datasets.
- Include letters of support from multiple IGVF partner institutions or collaborators confirming their commitment to using your coordinating center's services.
- Clearly articulate the staffing plan with CVs or biosketches of key personnel (data managers, bioinformaticians, database administrators) and their roles in consortium coordination.
⚠️ Common mistakes
Applications often fail when they lack demonstrated capacity for large-scale data management or fail to establish strong partnerships within the IGVF consortium beforehand. Weak technical infrastructure descriptions, vague coordination plans, or unclear staffing models also reduce competitiveness. Additionally, applicants sometimes overcommit to services without realistic timeline or budget justification, leading to concerns about feasibility.
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