Health and Extreme Weather Research Coordination and Data Center (U2C – Clinical Trial Not Allowed)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 15, 2026
Can you apply?
This grant is for research institutions and coordinating centers supporting the Health and Extreme Weather (HEW) initiative. Applicants must demonstrate capacity to serve as a coordinating or data support hub for a national research community of practice. Organizations must be able to facilitate multi-stakeholder engagement, manage research infrastructure, and provide data science support and training.
The coordinating component leads engagement across HEW grantees and the broader community of practice. The data component develops infrastructure to support health and environmental data access, sharing, and harmonization. Both components work in close partnership.
This is a cooperative agreement requiring substantial NIH programmatic involvement. Federal staff will be engaged in day-to-day management and decision-making throughout the project.
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Key dates
- Jun 26, 2026 Applications open
- Jan 29, 2027 Application deadline in 197 days
- Dec 1, 2027 Award announced
- Dec 2, 2027 Project start
Program description
The National Institute of Environmental Health Sciences (NIEHS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research coordination and data support for the Health and Extreme Weather (HEW) initiative. This solicitation will include two closely aligned components: research coordination and data support. The coordinating component will be responsible for facilitating engagement across the initiative’s NIH grantees and the larger HEW community of practice (CoP). This component will share best practices across the CoP, create training and educational resources, organize working groups and larger meetings, and otherwise disseminate information to the HEW CoP. The data component will develop resources and infrastructure to facilitate access to and use of health and environmental data by the HEW CoP. The data component will identify data-related needs in the CoP, provide training to address these needs, support sharing and linking of health, environmental, and geospatial data, and collaborate with other NIH data initiatives to reduce duplication, advance data science, and promote the use of data standards and harmonization. The coordinating and data components will be required to work in close partnership with each other to coordinate training, education, dissemination, and other research support activities. This NOFO will utilize the U2C activity code, which the National Institutes of Health (NIH) uses to support high impact research and research infrastructure activities. The U2C is a cooperative agreement that requires substantial federal programmatic staff involvement. Grant authorities that allow NIEHS to forecast this opportunity are as follows: 42 USC 285l (NIEHS specific); 42 USC section 241 (NIH grant authorities).
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (R&R) form
- Project Narrative/Research Plan
- Budget and Budget Narrative
- Organizational capacity documentation
- Letters of support from HEW stakeholders
- Institutional endorsement
Program contact
- 👤 NIEHS Division of Extramural Research and Training
- 📧 NOFO.Information@niehs.nih.gov
- 📞 Please contact via e-mail
Funding track record
Recent awards under CFDA 93.113 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$200,640,187
-
$49,163,443
-
$47,446,509
-
$44,785,560
-
$33,491,440
-
$32,623,202
-
$31,263,603
-
$30,390,185
-
$30,320,471
-
$29,228,555
Top States by Funding
- NC 10 awards $369.0M
- NY 11 awards $187.6M
- CA 11 awards $177.3M
- MA 7 awards $127.8M
- MD 5 awards $52.2M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.113). How funding has trended year over year.
| 2024 | $445,816,844 | |
| 2025 | $465,862,818 | |
| 2026 est. | $40,301,265 |
FAQ
Who can apply for this grant?
Research institutions, universities, and coordinating centers with proven capacity to manage research networks and data infrastructure. You need demonstrated ability to engage diverse stakeholders and provide training.
What are the two main components I should focus on?
Research coordination (community of practice engagement, training, knowledge sharing) and data support (infrastructure, harmonization, training). Both must work together.
Is this a traditional grant or something different?
This is a cooperative agreement (U2C), meaning NIH staff will be involved in substantive program management. Expect closer collaboration and oversight than typical grants.
What makes a competitive application?
Clear plan for serving the entire HEW research community. Demonstrate expertise in research coordination, data science, and multi-institutional partnerships. Show understanding of data harmonization and standards.
What's the funding and timeline?
Total pool is $3M. Deadline is January 29, 2027. No cost sharing required. Specific award ranges were not specified in the announcement.
💡 Tips for applicants
- Position yourself as a neutral convenor of the HEW community, not a competitor pursuing your own research agenda. Coordination and facilitation are central.
- Show past experience managing research networks, cooperative agreements, or large multi-institutional projects. References from previous partners are valuable.
- Plan concrete outputs: training materials, working groups, data tools, dissemination products. Vague coordination plans will not be competitive.
- Address both components equally. This is not primarily about data science alone—community engagement and training are equally important.
- Clarify how your data infrastructure aligns with broader NIH data initiatives. Show you've researched existing systems and where you add value.
⚠️ Common mistakes
Applications that focus only on data infrastructure without adequate attention to community coordination and training. Unclear governance structure or decision-making process for the community of practice. Failure to address how the two components (coordination and data support) will work together in practice.
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