Forecast to Publish a Funding Opportunity Announcement for Copy of Integrative Neuroscience Initiative on Alcoholism (INIA) Consortia Administrative Resource Core (U24) (Clinical Trial Optional)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 15, 2026
Can you apply?
This grant is for NIH-funded research consortia studying alcohol use disorder and excessive alcohol drinking. Eligible applicants are typically research institutions, universities, and organizations with established research capacity and staff with relevant expertise in neuroscience, alcohol research, or related fields.
The grant supports collaborative, multisite research consortia through cooperative agreement mechanisms. Individual research projects within consortia use the U01 activity code. Administrative and resource cores are required components of each consortium.
Applications are not currently being solicited. This is advance notice for potential applicants to develop collaborations and prepare competitive projects for the future funding opportunity announcement.
Not the right fit? Find grants for your organization in 5 questions →
Key dates
- May 6, 2025 Applications open
- May 1, 2026 Application deadline
- Feb 1, 2027 Award announced
- Feb 1, 2027 Project start
Program description
The purpose is to renew the NIAAA Integrative Neuroscience Initiative on Alcoholism (INIA). The INIA renewal will support two collaborative research consortia through an open competition to study brain-body homeostatic dysregulation that promotes and perpetuates excessive alcohol drinking and related Alcohol Use Disorder (AUD) phenotypes. We encourage hypothesis-centered research on interactions between alcohol and other relevant causal influences. Focus on trajectories from initial alcohol exposure to the development of pathological drinking by some individuals will identify translatable markers and mechanisms to support future prevention and intervention efforts that reduce the chronic conditions associated with alcohol misuse including but not limited to AUD. To promote innovation, investigators will adapt advanced tools and technologies from the BRAIN Initiative, NIH Common Fund, and other sources to examine brain structure and function at multiple spatial and temporal scales, from microcircuitry to whole brain networks, and reveal peripheral influences on brain function underlying excessive alcohol drinking. To promote rigor and reproducibility, a focus on standardization of neurofunctional measures and replication will be instituted across both consortia. In the context of the initiative, integration occurs with: (1) projects across multiple participating sites addressing objectives around a central hypothesis, (2) knowledge of actions and interactions at multiple biological scales of analysis, (3) shared resources and standardized experimental protocols, and (4) cross-species translation. The initiative renewal will support two collaborating multisite consortia though cooperative agreement mechanisms, each comprised of administrative and resource cores, and U01s for individual research projects. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of integrative neuroscience are encouraged to begin to consider applying for this new NOFO.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- NIH R&R Application components (specific forms vary by activity code)
- Detailed consortium organizational structure and governance
- Administrative Core budget and staffing plan
- Resource Core description and budget
- Individual U01 research project narratives and budgets
- Letters of commitment from all participating sites
- Vertebrate animal use protocol (if applicable)
Program contact
- 👤 Mark Egli
- 📧 Mark.Egli@nih.gov
- 📞 301-594-6382
Funding track record
Recent awards under CFDA 93.273 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$125,900,663
-
$34,675,742
-
$34,469,501
-
$33,261,336
-
$32,897,567
-
$31,652,514
-
$30,394,602
-
$29,223,384
-
$29,195,978
-
$29,168,993
Top States by Funding
- CA 15 awards $242.3M
- NY 3 awards $162.6M
- OR 7 awards $96.3M
- NC 4 awards $67.1M
- IN 3 awards $57.4M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.273). How funding has trended year over year.
| 2024 | $430,377,419 | |
| 2025 | $429,906,735 | |
| 2026 est. | $12,401,560 |
FAQ
What research areas are prioritized under INIA?
The initiative focuses on brain-body homeostatic dysregulation that promotes excessive alcohol drinking and alcohol use disorder. Research on trajectories from initial alcohol exposure to pathological drinking is especially encouraged.
What organizational structure is required?
Applications must organize as multisite consortia with administrative cores, resource cores, and multiple U01 research projects addressing a central hypothesis.
Can individual labs apply outside a consortium?
No. This mechanism requires collaborative multisite consortia. Individual researchers must participate as part of an organized consortium with shared resources and standardized protocols.
When will applications be accepted?
This is advance notice only. A formal funding opportunity announcement will be issued by May 2026. Applications are not currently being solicited.
What tools and technologies should projects use?
Projects should adapt advanced tools from the BRAIN Initiative and NIH Common Fund to examine brain structure and function across multiple spatial and temporal scales.
💡 Tips for applicants
- Begin developing multisite collaborations now. This is advance notice to allow time for meaningful partnership building before the formal NOFO is released.
- Design research around a central hypothesis that unites all consortium projects. Integration across sites and scales is a core requirement.
- Include standardized experimental protocols and a focus on reproducibility and replication across your consortium sites.
- Plan for both administrative and resource core components. These support the research projects and are essential consortium infrastructure.
- Consider incorporating cross-species translation and multiple biological scales of analysis. Innovation in study design and tool use strengthens competitiveness.
⚠️ Common mistakes
Submitting as individual research projects rather than organized multisite consortia. Failing to establish shared resources, standardized protocols, and central hypotheses linking all projects. Neglecting the administrative and resource core requirements that support consortium operations.
Similar grants
- CLOSED Forecast to Publish a Funding Opportunity Announcement for Integrative Neuroscience Initiative on Alcoholism (INIA) Consortia (U01 Clinical Trial Optional) — National Institutes of Health
- CLOSED Forecast to Publish a Funding Opportunity Announcement for Copy of Integrative Neuroscience Initiative on Alcoholism (INIA) Consortia Research Resource (U24) (Clinical Trial Optional) — National Institutes of Health
- OPEN Forecast to Publish a Funding Opportunity Announcement for Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Research Project — National Institutes of Health
- OPEN Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource (U24 Clinical Trials Optional) — National Institutes of Health
- CLOSED Forecast to Publish a Funding Opportunity Announcement for the Consortium on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Research Resource (Collaborative U24 – Clinical Trials not all — National Institutes of Health