Forecast to Publish a Funding Opportunity Announcement for the Consortium on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Research Resource (Collaborative U24 – Clinical Trials not all
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 15, 2026
Can you apply?
This grant is for research institutions and investigators studying the neurobiology of adolescent alcohol exposure and its effects on adult brain development and outcomes. U24 cooperative agreements support research networks and consortia. Applicants must propose collaborative, multi-institutional research combining relevant expertise.
Clinical trials are not allowed under this mechanism. Notice is provided in advance; formal applications are not currently being solicited. Eligible organizations typically include universities, medical centers, and research institutions with alcohol research capacity.
The initiative focuses on mechanisms linking adolescent drinking to persistent changes in brain-behavior relationships. Funded projects will contribute to developing better treatments and prevention strategies for alcohol-related problems.
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Key dates
- May 22, 2025 Applications open
- Sep 30, 2025 Application deadline
- May 30, 2026 Award announced
- May 30, 2026 Project start
Program description
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) consortium to elucidate mechanisms of persistent changes in brain-behavior relationships following adolescent alcohol exposure. The initiative supports research across various research institutions to investigate the mechanisms responsible for the effects of repeated adolescent alcohol exposure on brain maturation and adult outcomes. To establish a robust foundational knowledge base that can be utilized in developing enhanced treatment methods and more effective strategies for preventing alcohol and alcohol-related problems. NIAAA supports research across various fields, including biomedical and genetic factors, psychological and environmental influences, alcohol-related problems and medical conditions, health services research, and prevention and treatment strategies. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise in molecular insights are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise are encouraged, and these investigators should also begin considering applying for this application.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (R&R) form
- Project Narrative
- Biographical Sketches (key personnel)
- Budget and Budget Justification
- Letters of Institutional Support (for collaborating sites)
- Data Management Plan
- Biographical sketches and institutional commitment letters from all participating sites
Program contact
- 👤 Mohammed Akbar, Ph.D National Institute on Alcohol Abuse and Alcoholism
- 📧 akbarm@mail.nih.gov
- 📞 301-443-6009
Funding track record
Recent awards under CFDA 93.273 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$125,900,663
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$34,675,742
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$34,469,501
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$33,261,336
-
$32,897,567
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$31,652,514
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$30,394,602
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$29,223,384
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$29,195,978
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$29,168,993
Top States by Funding
- CA 15 awards $242.3M
- NY 3 awards $162.6M
- OR 7 awards $96.3M
- NC 4 awards $67.1M
- IN 3 awards $57.4M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.273). How funding has trended year over year.
| 2024 | $430,377,419 | |
| 2025 | $429,906,735 | |
| 2026 est. | $12,401,560 |
FAQ
Who can apply for this grant?
Research institutions with experience in alcohol research and neurobiology. Collaborative, multi-institutional teams are encouraged. Clinical trial proposals are not eligible.
When is the deadline?
The Notice of Funding Opportunity is forecasted for publication. The application deadline is expected to be September 30, 2025. Applicants should begin developing collaborations now.
What research activities are supported?
Studies of how adolescent alcohol exposure affects brain development and adult outcomes. Research on mechanisms, biomedical/genetic factors, and prevention strategies are all in scope.
What makes a competitive application?
Strong collaborative teams combining multiple research expertise areas. Clear mechanisms explaining how adolescent drinking leads to adult brain-behavior changes. Feasibility and experienced leadership.
What is a U24 cooperative agreement?
U24s support research networks and resource development. These are collaborative mechanisms requiring applicant-NIH interaction and communication. Awards typically fund coordination and collaborative science.
💡 Tips for applicants
- Start building collaborations now. This is a forecasted funding opportunity, so use the advance notice to develop meaningful research partnerships.
- Emphasize mechanistic understanding of how adolescent alcohol exposure causes persistent adult brain changes. The grant prioritizes neurobiology pathways.
- Include multiple complementary research expertise and institutions. U24s are designed for consortia, not single-site projects.
- Avoid proposing clinical trials. The NOFO explicitly excludes clinical trial designs.
- Prepare preliminary data showing feasibility. Competitive U24 applications demonstrate institutional commitment and realistic timelines.
⚠️ Common mistakes
Applications proposing clinical trials will be rejected. Avoid single-institution projects without clear collaborative structure. Weak description of mechanisms linking adolescent drinking to adult outcomes.
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