Drug Use and Addiction Research Programs

CFDA 93.279 Active Grant Cooperative Agreement

Open Opportunities (36)

Live Grants.gov opportunities funded under this program — you can apply now.

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Program Funding

Annual program obligations reported to SAM.gov.

Latest annual funding (estimated)
$20.2M FY2026
$1.25B
FY24
$1.34B
FY25
$20.2M
FY26*
* estimated

Who has received this funding

Organizations awarded under CFDA 93.279 (USAspending.gov).

Program Objective

To support basic, clinical, translational, and implementation research in the field of substance use. To develop new knowledge and approaches for the prevention, diagnosis, and treatment of drug use, misuse, and addiction, drug overdose, and related health outcome, including HIV/AIDS. To support research training and research scientist development. To support dissemination of research findings.
Small Business Innovation Research (SBIR) legislation is intended to expand and improve the SBIR programs to emphasize and increase private sector commercialization of technology developed through Federal SBIR research and development; increase small business participation in Federal research and development; and foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in the SBIR program. The Small Business Technology Transfer (STTR) legistlation is intended to stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions; foster technology transfer between small business concerns and research institutions; increase private sector commercialization of innovations derived from Federal research and development; and foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation.

Eligibility

Eligible Applicants

  • Nonprofit Organization
  • U.S. State Government
  • U.S. Territory Government
  • Federally Recognized Tribal Government
  • Tribal Government (other)
  • Tribally Designated Housing Authority
  • Municipality/Township Government
  • Public Housing Authority
  • Foreign Nonprofit Organization
  • Foreign Not-for-Profit Organization
  • Foreign For-Profit Organization
  • Not-for-Profit Organization
  • For-Profit Organization
  • Other

Eligible organizations determined at the NOFO level

How to Apply

Award Procedure

Grants with which the National Advisory Council on Drug Abuse has concurred with the recommendations of the Scientific Review Groups and approved by NIDA for payment are awarded directly by NIDA to the applicant institution. SBIR/STTR applications are evaluated for scientific and technical merit by an appropriate scientific peer review panel and by the National Advisory Council. All applications receiving a priority score compete for available SBIR/STTR set-aside funds on the basis of scientific and technical merit and commercial potential of the proposed research, program relevance, and program balance among the areas of research.

From 240 to 270 days from submission of grant application. For AIDS applications the range will not exceed 180 days from cited receipt dates. SBIR/STTR applications: About 225 days.

Program details & compliance

Description

To support basic, clinical, translational, and implementation research in the field of substance use. To develop new knowledge and approaches for the prevention, diagnosis, and treatment of drug use, misuse, and addiction, drug overdose, and related health outcome, including HIV/AIDS.

Mission Categories

Primary: Prevention and Control (includes Suicide Prevention)

Other categories:
BiologyResearch and DevelopmentSocial Sciences

Use of Funds

Allowed Uses

(1) Research project grants provide support for clearly defined projects or a small group of related research activities, and when appropriate, support of research conferences; (2) program project and center grants support large-scale, broad-based programs of research, usually interdisciplinary, consisting of several projects with a common focus; (3) small grants support newer, less experienced investigators; investigators at institutions without a well-developed research tradition and resources; the testing of new methods or techniques; small-scale exploratory and pilot studies, or exploration of an unusual research opportunity; (4) research training grants including fellowships and institutional training grants, career development grants and loan repayment contracts; (5) SBIR Phase I grants (of approximately 6-months' duration) are to establish the technical merit and feasibility of proposed research or research and development efforts to determine the quality of performance of the small business grantees. Phase II grants are for the continuation of the research initiated in Phase I and that are likely to result in commercially viable products or processes. STTR Phase I grants (normally of 1-year duration) are to determine the scientific, technical, and commercial merit and feasibility of the proposed cooperative effort that has potential for commercial application and the quality of performance of the small business concerns. Phase II funding is based on results of research initiated in Phase I and scientific and technical merit and commercial potential of the Phase II application.

Reporting & Compliance

Audit Required
Yes — Annual
Records Retention
3 years

Applicable 2 CFR 200 Subparts

  • Subpart B — General Provisions
  • Subpart C — Pre-Federal Award Requirements
  • Subpart D — Post-Federal Award Requirements
  • Subpart E — Cost Principles
  • Subpart F — Audit Requirements

Contacts

Jeanette Marketon — Committee Management Officer, NIDA
301-443-5239
National Institute on Drug Abuse 3WFN MSC 6024 16071 Industrial Dr. - Dock 11, Gaithersburg, MD 20892
Molly Cluster
3014350503
National Institute on Drug Abuse 3WFN MSC 6024 16071 Industrial Dr. - Dock 11,, Gaithersburg, MD 20892
Data from SAM.gov Federal Assistance Listings. Source published: 2026-02-10. Spec v2.0. Last synced: 2026-05-28 07:28:37.

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