Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 16, 2026
Can you apply?
This grant is for research institutions and organizations seeking to fund dissemination and implementation research in health. Eligible applicants include universities, colleges, tribal institutions, faith-based organizations, community-based organizations, federal agencies, and non-domestic entities. The grant supports studies that identify, develop, and test strategies for adopting and integrating evidence-based health interventions and practices. Research must fall within the mission of at least one NIH Institute or Center. De-implementation research to eliminate ineffective or harmful practices is also supported.
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Program description
The purpose of this Notice of Funding Opportunity (NOFO) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, sustainability, scale-up, and spread of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies (hereafter referred to as evidence-based interventions). Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged. Applications that focus on re-implementation of evidence-based health services that may be disrupted amidst disasters (e.g., pandemics) remain relevant. All applications must be within the scope of the mission of one of the Institutes/Centers listed above.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- County Government
- Faith-based Organization
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Researcher (independent)
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (R&R) Application for Federal Assistance
- Project Narrative (Research Plan)
- Budget and Budget Justification
- Biographical Sketches (for key personnel)
- Current and Pending Support documentation
- Facilities and Administrative Costs information
Program contact
- 👤 National Institutes of Health
- 📧 grantsinfo@nih.gov
- 📞 301-402-2541
Funding track record
Recent awards under CFDA 93.279 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$204,359,786
-
$128,078,833
-
$126,585,435
-
$99,478,296
-
$79,333,238
-
$78,351,755
-
$74,806,844
-
$71,588,047
-
$61,578,651
-
$50,952,037
Top States by Funding
- NY 4 awards $260.8M
- WA 1 awards $204.4M
- CT 2 awards $155.8M
- CA 4 awards $141.1M
- MD 2 awards $128.2M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.279). How funding has trended year over year.
| 2024 | $1,245,503,136 | |
| 2025 | $1,343,517,098 | |
| 2026 est. | $20,194,375 |
FAQ
What types of research does this grant fund?
Studies that develop strategies to overcome barriers to adoption and integration of evidence-based health interventions. De-implementation research to stop using ineffective or harmful practices is also eligible.
Who can apply for this grant?
Universities, colleges, tribal institutions, faith-based and community-based organizations, federal agencies, and foreign organizations can apply. Research must fit within an NIH Institute or Center's mission.
What is the deadline?
January 7, 2028. This is a fixed deadline for this funding opportunity.
What budget categories are allowed?
Personnel, equipment, and supplies are typically allowable. Specific budget limits depend on your institute/center. Consult the NIH grants page for your specific IC.
How competitive is this funding?
NIH R01 grants are highly competitive. Strong preliminary data, clear research design, and experienced teams significantly improve success rates. Plan for substantial preparation time.
💡 Tips for applicants
- Start with a clear problem statement. Explain what barrier you will address and why it matters for health outcomes. Focus on one major barrier per aim.
- Build your research team early. Include experts in implementation science, the health domain, and statistical analysis. External collaborators strengthen applications.
- Develop realistic timelines and budgets. NIH reviewers scrutinize feasibility. Show you understand resource constraints and have contingency plans.
- Use existing frameworks and tools. Cite dissemination and implementation science models (RE-AIM, CFIR, etc.). This demonstrates rigor and knowledge of the field.
- Pilot your methods if possible. Preliminary data dramatically improves competitiveness. Even small pilot studies show feasibility and strengthen your narrative.
⚠️ Common mistakes
Lack of preliminary data or pilot work weakens competitiveness. Unfocused scope that tries to address multiple unrelated barriers dilutes impact. Proposing purely theoretical work without clear connection to real-world health practice or clear implementation outcomes.
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