Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT) Infrastructure – Clinical Coordinating Center (CCC) & Data Coordinating Center (DCC)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Oct 8, 2026
Can you apply?
This grant is for research institutions and centers that can establish clinical trial infrastructure for neurological disorders. Applicants must be able to serve as either a Clinical Coordinating Center or Data Coordinating Center supporting the NeuroNEXT network. Eligible organizations typically include academic medical centers, research hospitals, and established research institutions with experience in multi-site clinical trials. Applications focus on infrastructure support for adult and pediatric neurology research conducted through collaborative networks.
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Key dates
- Sep 10, 2026 Applications open
- Nov 1, 2027 Application deadline in 388 days
- Jul 1, 2028 Award announced
- Jul 1, 2028 Project start
Program description
The National Institute of Neurological Disorders and Stroke (NINDS), at the National Institutes of Health (NIH) seek to continue support for the Infrastructure for the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT). NeuroNEXT conducts clinical trials and biomarker validation studies for neurological disorders in adult and pediatric populations. By offering infrastructure, expertise, and collaborative opportunities, NeuroNEXT accelerates innovation and impact, advancing the development of safe, effective neurotherapeutics for patients through high-quality evidence pathways. The program will encourage applications for a Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC) to support NeuroNEXT.
Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications for centers.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (R&R)
- Project Narrative
- Budget and Budget Justification
- Organizational Capacity/Infrastructure Documentation
- Letters of Institutional Support
- Data Management and Quality Assurance Plans
- Multi-site Collaboration Agreements
Program contact
- 👤 National Institute of Neurological Disorders & Stroke (NINDS)
- 📧 NEXT1@ninds.nih.gov
- 📞 Please contact via e-mail.
Funding track record
Recent awards under CFDA 93.853 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$56,262,774
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$45,083,283
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$43,730,658
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$38,186,781
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$37,769,493
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$35,655,349
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$35,655,116
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$34,183,297
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$32,294,153
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$32,164,022
Top States by Funding
- MA 7 awards $186.3M
- CA 6 awards $163.5M
- FL 4 awards $121.0M
- OH 4 awards $112.5M
- NY 3 awards $91.7M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.853). How funding has trended year over year.
| 2024 | $2,362,835,459 | |
| 2025 | $2,345,500,401 |
FAQ
Who can apply for this grant?
Research institutions, medical centers, and organizations with infrastructure capacity to coordinate multi-site clinical trials in neurology. Experience with NIH-funded research and clinical trial coordination is essential.
What is the deadline for applications?
The deadline is fixed at November 1, 2027. This is a long timeline. Start building collaborations and partnerships early.
What activities does the grant support?
The grant supports infrastructure for clinical coordinating centers and data coordinating centers. These centers manage logistics, data management, and coordination for multi-site clinical trials in neurological disorders.
How competitive is this grant?
This is highly competitive. It supports major research infrastructure. Strong preliminary data, established research networks, and institutional commitment are needed.
What is the typical funding range?
Award amounts are not publicly specified. Contact NIH program staff for guidance on budget expectations for CCC and DCC awards.
💡 Tips for applicants
- Start building partnerships with other research sites immediately. Multi-site networks are critical for success.
- Demonstrate existing capacity in clinical trial management and data systems. Show past experience with comparable studies.
- Include letters of commitment from collaborating sites. Establish clear governance and communication structures.
- Emphasize your center's infrastructure investments and dedicated staff. Sustainability planning is important.
- Contact the NINDS program officer early. Clarify expectations for CCC vs. DCC roles and budget ranges.
⚠️ Common mistakes
Underestimating the complexity of multi-site coordination. Weak collaboration agreements or unclear roles between partner institutions. Insufficient detail on data management systems and quality assurance procedures.
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