Stroke Clinical Trials Network (StrokeNet) Infrastructure – Regional Coordinating Stroke Centers (RCCs)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Oct 8, 2026
Can you apply?
This grant is for healthcare systems and research institutions supporting NIH stroke clinical trials. Eligible applicants are accredited medical centers with expertise in stroke care and clinical research infrastructure. Organizations must demonstrate capacity to enroll patients in acute stroke, stroke prevention, and stroke recovery trials. Regional coordinating centers will support the NIH StrokeNet network across multiple sites.
Organizations must have established stroke programs, IRB capacity, and clinical research staff. Preference is typically given to centers with strong relationships with community hospitals and diverse patient populations. Multi-institutional consortia are encouraged to apply as regional coordinating centers.
Not the right fit? Find grants for your organization in 5 questions →
Key dates
- Sep 10, 2026 Applications open
- Jan 25, 2028 Application deadline in 473 days
- Dec 1, 2028 Award announced
- Dec 1, 2028 Project start
Program description
The National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH) seek to continue to support the Infrastructure for the NIH Stroke Clinical Trials Network (NIH StrokeNet). The program will encourage applications for network regional clinical enrollment coordinating centers (RCC’s) to support the NIH StrokeNet clinical trial network. The NIH StrokeNet conducts clinical trials focused on advancing acute stroke treatment, stroke prevention, and stroke recovery and rehabilitation across the lifespan. Its mission is to improve outcomes for individuals who experience stroke by evaluating promising new therapies for patients with stroke and those at risk for stroke.
Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications for centers.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (R&R) form
- Project Narrative
- Budget Justification
- Biographical Sketches (key personnel)
- Budget (NIH Form)
- Letters of Support (partner institutions)
- Organization capacity documentation
- Curriculum Vitae (key staff)
Program contact
- 👤 National Institute of Neurological Disorders & Stroke (NINDS) StrokeNet
- 📧 strokenetinquiry@mail.nih.gov
- 📞 Please contact via e-mail.
Funding track record
Recent awards under CFDA 93.853 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$56,262,774
-
$45,083,283
-
$43,730,658
-
$38,186,781
-
$37,769,493
-
$35,655,349
-
$35,655,116
-
$34,183,297
-
$32,294,153
-
$32,164,022
Top States by Funding
- MA 7 awards $186.3M
- CA 6 awards $163.5M
- FL 4 awards $121.0M
- OH 4 awards $112.5M
- NY 3 awards $91.7M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.853). How funding has trended year over year.
| 2024 | $2,362,835,459 | |
| 2025 | $2,345,500,401 |
FAQ
What types of organizations can apply?
Academic medical centers, hospital systems, and research institutions with established stroke programs and clinical trial infrastructure. Centers must demonstrate capacity to coordinate multi-site enrollment.
What is the main purpose of this funding?
To establish regional coordinating centers that support enrollment and conduct of NIH StrokeNet clinical trials. These centers coordinate across multiple hospitals and patient populations.
Are there geographic requirements?
Yes. Centers must be positioned to serve a defined geographic region and coordinate stroke trials across multiple sites within that region.
What activities are supported?
Patient recruitment and enrollment, trial coordination, data management, regulatory compliance, and communication between trial sites and the central network office.
When is the next deadline?
The deadline is January 25, 2028. Applications are not currently being solicited; this notice allows time for collaboration planning.
💡 Tips for applicants
- Establish partnerships early with hospital systems and clinical sites that will enroll patients in your region.
- Demonstrate existing stroke program infrastructure and clinical research experience at your organization.
- Show capacity to coordinate multiple sites and manage complex data systems for multi-center trials.
- Highlight diversity of patient populations your center can reach for stroke trials.
- Include letters of support from affiliated hospitals and community partners in your network.
⚠️ Common mistakes
Applying without established relationships with hospitals and clinical sites in your proposed service region. Underestimating the infrastructure and staffing needed to coordinate multi-site clinical trials. Failing to demonstrate current experience managing regulatory, compliance, and data systems for research.
Similar grants
- OPEN NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure – National Coordinating Center (NCC) and National Data Management Center (NDMC) — National Institutes of Health
- OPEN Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC) — National Institutes of Health
- OPEN Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT) Infrastructure – Clinical Research Sites (U24 Clinical Trial Not Allowed) — National Institutes of Health
- OPEN HIV/AIDS Clinical Trials Network Laboratory Centers — National Institutes of Health
- CLOSED Forecast to Publish a Funding Opportunity Announcement for EmbraceHealth Clinical Research Network to Reduce Health Disparities – Coordinating Center — National Institutes of Health