National and Regional Resources (R24 – Clinical Trial Not Allowed)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 15, 2026
Can you apply?
This grant is for researchers and research institutions seeking funding to develop and maintain national and regional research resources that support biomedical research across the U.S. Eligible applicants include universities, research institutions, nonprofit organizations, and other entities with strong research infrastructure. The grant specifically excludes clinical trial research, focusing instead on resource development, curation, and dissemination. Applicants must demonstrate how their resource will benefit a broad research community and provide long-term scientific value. Geographic scope is national, though resources may serve specific regions or research areas. Activities supported include creating databases, repositories, tissue banks, animal models, computational tools, and other research infrastructure that enables research in the biomedical sciences.
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Program description
This Notice of Funding Opportunity (NOFO) encourages applications for support of resources that will provide access to state-of-the-art equipment, technologies, research tools, materials, organisms, software, and/or services to a substantial regional (multi-state) or national user base. Only those resources with technical capabilities that fall within the NIGMS-supported program areas are eligible for awards. The resources should already be established or may be formed through consolidation of existing local or regional facilities. The intent is to provide resource access to investigators without regard to the specific biomedical focus of their research, while not duplicating or replacing resources supported by sources such as other NIH Institutes and Centers (ICs) or host institutions. The resource is expected to be maintained or upgraded to current best practices, make its capabilities and availability known to the biomedical research community through a robust web presence and outreach activities, and provide user training and support.
Who can apply
Eligible applicants
How to apply
Application links
Required documents
- SF-424 (R&R) form (federal application form)
- Project narrative (typically 15-25 pages describing the resource, its scientific rationale, and community impact)
- Budget narrative and detailed budget forms (SF-424 R&R Budget)
- Institutional commitment and cost-sharing documentation
- Letters of support from potential resource users
- Biosketches of key personnel
- Current and pending support disclosure
- Data management and sharing plan
- Resource sustainability and maintenance plan
Program contact
- 👤 National Institutes of Health
- 📧 grantsinfo@nih.gov
- 📞 301-402-2541
Funding track record
Recent awards under CFDA 93.859 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$59,464,779
-
$57,271,194
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$56,019,458
-
$54,912,096
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$53,329,877
-
$52,858,544
-
$52,347,059
-
$52,026,661
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$50,897,104
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$49,349,731
Top States by Funding
- ME 4 awards $143.3M
- MS 4 awards $135.1M
- NY 5 awards $131.6M
- CA 5 awards $129.3M
- RI 4 awards $126.3M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.859). How funding has trended year over year.
| 2024 | $3,085,929,426 | |
| 2025 | $3,092,472,727 | |
| 2026 est. | $3,093,422,000 |
FAQ
Who is eligible to apply for this grant?
Eligible applicants typically include U.S. research institutions such as universities, medical schools, research centers, nonprofits, and other organizations with demonstrated research capacity. Individuals cannot apply directly; applications must come from institutions.
When is the deadline?
The application deadline is June 14, 2027, with the application period opening June 11, 2025. These are fixed deadlines, so there is no flexibility.
What types of research resources can be funded?
This grant supports development and maintenance of shared research resources such as databases, biorepositories, animal models, computational tools, reagent banks, and other infrastructure that serve the broader research community.
Why are clinical trials excluded from this grant?
Clinical trials are excluded because NIGMS R24 funding is designed for research infrastructure and resource development, not direct clinical research. Clinical research should be pursued through other NIH mechanisms.
What is the typical funding range?
R24 grants typically fund in the $250,000-$500,000 annual range, though amounts vary based on resource scope and need. Detailed budget information should be obtained from the official NIGMS solicitation.
💡 Tips for applicants
- Emphasize the broad utility of your resource: clearly articulate how your resource will benefit multiple research teams and advance science across the biomedical field, not just support your own lab's work.
- Demonstrate sustainability planning: show how the resource will be maintained long-term, including staffing, infrastructure, and a realistic budget that accounts for ongoing costs.
- Provide evidence of community need: include letters of support from potential users, data on current usage of similar resources, and documentation of unmet needs in your research area.
- Build in strong data management and access protocols: explain how researchers will discover, access, and use your resource, including data sharing policies, user support, and quality assurance measures.
- Align with NIH priorities: ensure your resource addresses current research needs and complements existing NIGMS-supported resources; avoid unnecessary duplication by reviewing existing NIH resource catalogs.
⚠️ Common mistakes
Applications often fail when they lack clear demonstration of broad scientific utility beyond the applicant's immediate research group. Another common pitfall is insufficient detail on sustainability—reviewers need to see realistic long-term funding plans and institutional commitment. Additionally, proposals that closely duplicate existing NIH-funded resources, or that propose clinical trial endpoints rather than basic research infrastructure, are typically not competitive.
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