The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Genomic Research Centers
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 15, 2026
Can you apply?
This grant is for biomedical researchers studying inflammatory bowel disease genetics at genomic research centers.
Eligible applicants include academic institutions, research hospitals, and nonprofit research organizations with doctoral-level research programs. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) typically requires institutional research infrastructure and compliance with federal regulations.
Grants support multi-disciplinary genomic research focused on IBD genetic mechanisms, biomarkers, and therapeutic targets. Participation in the Consortium is required, meaning collaboration with other funded research centers.
This is a federal research program. Applicants must have appropriate institutional review and administrative capacity to manage federal funding.
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Key dates
- Sep 18, 2025 Applications open
- Nov 1, 2026 Application deadline in 108 days
- Jul 1, 2027 Award announced
- Jul 1, 2027 Project start
Program description
The National Institute of Diabetes and Digestive Diseases and Nutrition (NIDDK) seeks to advance its mission by continuing the NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC). The IBDGC has led collaborative efforts resulting in the identification of >300 genetic risk loci for different IBD subtypes across patient populations and characterization of underlying biological mechanisms. Despite advances in biological understanding and the development of a range of biologic therapies, IBD remains a chronic, severe and heterogenous disease with no cure requiring multiple interventions over the life course. Diagnostic biomarkers and accurate predictors of critical outcomes including disease remission, recurrence, and response to specific therapies are lacking. The IBDGC will leverage patient cohorts, biospecimens and advances in data science to characterize the interactions of genetic, clinical and environmental factors in disease development and progression, and to develop new predictors of disease outcomes, with the goal of improving medical management and advancing precision medicine for IBD patients. The IBDGC may include up to 7 Genomic Research Centers with varying research emphases, which will serve as sites for participant enrollment, molecular analysis of biospecimens and bioinformatics and computational analyses.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (federal application form)
- Project Narrative and Specific Aims
- Research Design and Methods
- Preliminary Data section
- Budget and Budget Justification
- Institutional Support Letter
- Biographical Sketches (Key Personnel)
- Facilities and Resources documentation
- Letters of Collaboration (consortium partners)
- NIH Compliance forms (IRB, IACUC, biosafety certifications as applicable)
Program contact
- 👤 Ludmila Pawlikowska Ph.D.
- 📧 Ludmila.pawlikowska@nih.gov
- 📞 301-480-9372
Funding track record
Recent awards under CFDA 93.847 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$438,527,853
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$200,221,259
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$152,979,352
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$112,529,392
-
$66,521,567
-
$45,186,589
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$39,699,167
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$37,490,770
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$34,242,949
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$31,624,784
Top States by Funding
- WA 3 awards $492.3M
- NC 4 awards $291.6M
- FL 2 awards $184.1M
- MA 6 awards $168.4M
- PA 6 awards $168.1M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.847). How funding has trended year over year.
| 2024 | $1,971,472,000 | |
| 2025 | $2,043,166,000 | |
| 2026 est. | $111,289,000 |
FAQ
Who can apply for this consortium grant?
Academic research institutions, medical schools, teaching hospitals, and research-focused nonprofits with established research programs are eligible. Your institution must have doctoral-level research capacity and institutional approval processes.
What types of research does this grant support?
Genomic and genetic research on inflammatory bowel disease mechanisms, etiology, and potential therapeutic targets. Studies examining IBD genetics, biomarkers, and precision medicine approaches are prioritized.
Is this a single grant or consortium funding?
This is consortium funding. Successful applicants must join the IBDGC network and collaborate with other funded centers. Coordination and data-sharing requirements apply.
What is the typical application difficulty?
This is highly competitive federal research funding. Applications require detailed scientific protocols, preliminary data, institutional support letters, and compliance documentation.
What is the funding range?
NIDDK research center grants typically fund $300K–$500K annually per center. Multi-year awards are common. Consult current program announcements for specific funding levels.
💡 Tips for applicants
- Establish consortium partnerships early. Success requires letters of collaboration from other research centers and clear communication roles.
- Present preliminary genomic data. Strong pilot data demonstrating your lab's capability to execute IBD genetic research is critical.
- Detail your sample cohort and biobank resources. Access to large, well-characterized IBD patient populations strengthens applications significantly.
- Align with NIDDK priorities. Review current strategic plans emphasizing precision medicine, health disparities, and mechanistic insights into IBD.
- Plan for data sharing. Federal grants require compliance with NIH data-sharing policies and the Consortium's data management standards.
⚠️ Common mistakes
Weak or missing preliminary genomic data demonstrating research feasibility. Insufficient documentation of IBD patient cohorts, biospecimens, or laboratory infrastructure. Failure to address consortium coordination, collaboration timelines, or data-sharing compliance requirements.
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