Mayo Clinic — Federal Grants & Funding Profile

Q: Is Mayo Clinic a nonprofit, and what is its EIN?

Mayo Clinic is a 501(c)(3) nonprofit (EIN 416011702).

Mayo Clinic has received 25 federal grant awards totaling $786.4M across 17 assistance programs and 2 federal agencies, based on USAspending.gov records aggregated by Grantoria.

25awards

$786.4Mtotal funding

$180.3Mlargest award

$31.5Mavg award

17programs

🏆 Top 5% by total funding · Top 10% by number of awards among U.S. federal grant recipients tracked by Grantoria.

Open grants Mayo Clinic could apply for now

Live opportunities in the federal programs Mayo Clinic has previously been funded under — sorted by upcoming deadline.

Paul B. Beeson Emerging Leaders Career Development Award in Aging
National Institutes of Health CFDA 93.866

Deadline: Jun 13, 2026 Closing soon
Novel Approaches to Support Therapeutic Development in Ultra-Rare Cancers
Food and Drug Administration CFDA 93.103

up to $500K Deadline: Jun 15, 2026 Closing soon
Intramural – Extramural Collaboration for Advanced 3-D Tissue Models for Drug Screening (Clinical Trial Not Allowed)
National Institutes of Health CFDA 93.350

Deadline: Jun 16, 2026 Closing soon
Awards Supporting Cutting-Edge Technologies for Translational Science (ASCETTS) (R21 Clinical Trials Not Allowed)
National Institutes of Health CFDA 93.350

Deadline: Jun 18, 2026 Closing soon
Research Project Cooperative Agreements in Aging and/or Alzheimer’s disease (AD) and Alzheimer’s disease-related dementias (ADRD) Research
National Institutes of Health CFDA 93.866

Deadline: Jun 20, 2026 Closing soon
Clinical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U01 Clinical Trial Optional)
National Institutes of Health CFDA 93.853

Deadline: Jun 22, 2026 Open
Analytical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders(U01 Clinical Trial Optional)
National Institutes of Health CFDA 93.853

Deadline: Jun 22, 2026 Open
Collaborative Opportunities for Multiple-disciplinary, Bold, and Innovative Neuroscience (COMBINE) (RM1 Clinical Trial Optional)
National Institutes of Health CFDA 93.853

Deadline: Jun 23, 2026 Open

Federal programs Mayo Clinic has been funded under

Top programs ranked by total funding received (17 programs in total).

21st Century Cures Act – Precision Medicine InitiativeCFDA 93.368 $180.6M
Cancer Centers Support GrantsCFDA 93.397 $177.7M
Extramural Research Programs in the Neurosciences and Neurological DisordersCFDA 93.853 $99.5M
Cancer Treatment ResearchCFDA 93.395 $95.5M
National Center for Advancing Translational SciencesCFDA 93.350 $70.8M
Aging ResearchCFDA 93.866 $39.7M
Cancer Cause and Prevention ResearchCFDA 93.393 $22.1M
Human Genome ResearchCFDA 93.172 $15.9M
Cancer Research ManpowerCFDA 93.398 $15.4M
Arthritis, Musculoskeletal and Skin Diseases ResearchCFDA 93.846 $14.7M
Discovery and Applied Research for Technological Innovations to Improve Human HealthCFDA 93.286 $12.2M
National Center on Sleep Disorders ResearchCFDA 93.233 $10.5M
Military Medical Research and DevelopmentCFDA 12.420 $9M
Lung Diseases ResearchCFDA 93.838 $8.6M
Cancer Detection and Diagnosis ResearchCFDA 93.394 $8.2M

Top awarding agencies

Department of Health and Human Services$777.4M
Department of Defense$9M

Where this funding went

Awards recorded across 1 state/territories: MN.

Similar grant recipients

Organizations funded under the same federal programs.

University of Washington 174 awards · $2.16B University of Wisconsin System 172 awards · $1.9B The Johns Hopkins University 143 awards · $2.49B The Trustees of Columbia University in the City of New York 136 awards · $2.58B Regents of the University of Michigan 133 awards · $2.12B University of California, San Diego 130 awards · $1.9B

Frequently asked questions

How much federal grant funding has Mayo Clinic received?

Mayo Clinic has received 25 federal grant awards totaling $786.4M, based on USAspending.gov assistance records aggregated by Grantoria.

Which federal agencies fund Mayo Clinic?

Its largest federal funders are Department of Health and Human Services, Department of Defense.

Is Mayo Clinic a nonprofit, and what is its EIN?

Mayo Clinic is a 501(c)(3) nonprofit (EIN 416011702), headquartered in Rochester, MN. See its IRS filings on ProPublica.

Can Mayo Clinic apply for grants that are open now?

Yes — there are federal grants open today in the same programs Mayo Clinic has previously been funded under. See the open grants section above.

Source: USAspending.gov assistance awards, aggregated by Grantoria. Historical record of awards received; not an endorsement or a guarantee of future funding.