Unveiling Health and Healthcare Disparities in Non-Communicable and Chronic Diseases in Latin America: Setting the Stage for Better Health Outcomes Across the Hemisphere (R01 – Clinical Trials Not All
Can you apply?
This grant is for researchers and institutions studying health disparities in chronic and non-communicable diseases across Latin America and the Caribbean region.
Eligible applicants include research institutions, universities, hospitals, and nonprofit organizations with research capacity. Domestic and international institutions can apply, though U.S.-based organizations are typical NIH grantees.
The grant supports investigator-initiated research projects examining disease burden, health equity, and systemic factors affecting chronic disease outcomes. Clinical trials are not allowed. Projects must advance understanding of health disparities and generate evidence for policy or practice improvements.
This grant is for researchers and institutions studying health disparities in chronic and non-communicable diseases across Latin America and the Caribbean region.
Eligible applicants include research institutions, universities, hospitals, and nonprofit organizations with research capacity. Domestic and international institutions can apply, though U.S.-based organizations are typical NIH grantees.
The grant supports investigator-initiated research projects examining disease burden, health equity, and systemic factors affecting chronic disease outcomes. Clinical trials are not allowed. Projects must advance understanding of health disparities and generate evidence for policy or practice improvements.
Program description
This Notice of Funding Opportunity (NOFO) will support innovative, collaborative, and multi-disciplinary research focused on clinical epidemiology, evaluation of public and/or health care policies, and validation of measurements that address health and health care disparities related to non-communicable and chronic diseases (NCDs) with the highest disease burden and mortality in Latin America and among U.S. Hispanics/Latinos. Multi-disciplinary research teams would be expected to meaningfully collaborate with key partners that must include at least one PI or MPI from institutions in Latin America.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- County Government
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
Demographic focus
Details
This grant is for researchers and institutions studying health disparities in chronic and non-communicable diseases across Latin America and the Caribbean region.
Eligible applicants include research institutions, universities, hospitals, and nonprofit organizations with research capacity. Domestic and international institutions can apply, though U.S.-based organizations are typical NIH grantees.
The grant supports investigator-initiated research projects examining disease burden, health equity, and systemic factors affecting chronic disease outcomes. Clinical trials are not allowed. Projects must advance understanding of health disparities and generate evidence for policy or practice improvements.
How to apply
Application links
Required documents
- SF-424 (R&R) form
- Project Narrative (Specific Aims, Research Design, Methods)
- Detailed Budget and Budget Justification
- Biosketches of key personnel
- Literature Cited
- Facilities and Resources documentation
- Letters of Support from collaborators
Program contact
- 👤 National Institutes of Health
- 📧 grantsinfo@nih.gov
- 📞 301-402-2541
Funding track record
Recent awards under CFDA 93.121 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$443,702,768
-
$32,310,944
-
$31,252,186
-
$29,535,192
-
$23,987,187
-
$23,513,241
-
$18,362,716
-
$16,829,492
-
$15,691,075
-
$14,460,130
Top States by Funding
- WA 2 awards $451.4M
- CA 13 awards $134.6M
- MI 4 awards $75.8M
- PA 4 awards $67.6M
- MA 5 awards $39.0M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.121). How funding has trended year over year.
| 2024 | $319,987,302 | |
| 2025 | $332,151,837 | |
| 2026 est. | $337,316,521 |
FAQ
What types of research are funded?
This grant funds observational studies, epidemiological research, health services research, and implementation science projects. Clinical trials are explicitly not allowed.
Who is eligible to apply?
Research institutions, universities, and nonprofit organizations with research infrastructure. Researchers in both the U.S. and Latin America can be applicants or collaborators.
What is the geographic scope?
Research must focus on Latin America and the Caribbean region. Comparative studies with other regions are permitted if the primary focus remains the hemisphere.
How competitive is this grant?
NIH R01 awards are highly competitive. Success rates typically range 10-25% depending on the Institute or Center. Strong preliminary data and clear innovation are essential.
What funding levels should I expect?
R01 grants typically provide $250,000-$500,000+ in annual direct costs, with project periods of 3-5 years. Actual amounts vary by Institute.
💡 Tips for applicants
- Establish strong collaborations with Latin American institutions to demonstrate regional expertise and community engagement.
- Use preliminary data showing disease burden and disparities in your target population or geography.
- Frame your research around actionable findings that can inform policy, clinical practice, or public health interventions.
- Address health equity explicitly by examining social determinants and structural factors driving disparities.
- Review recently funded projects in this area on NIH RePORTER to understand current priorities and competitive approaches.
⚠️ Common mistakes
Many applications lack sufficient preliminary data or community partnerships in Latin America. Proposals that lack clear health equity focus or policy relevance tend to be less competitive. Unclear methodology or overly ambitious scope for the proposed budget period weakens applications.
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