Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use
🏛 Centers for Disease Control - NCHHSTP
✓ Free, no account · Source: Grants.gov · Last verified Jul 27, 2026
Can you apply?
This grant is for organizations that provide services to people who use drugs (PWUD) and want to strengthen infectious disease prevention. Eligible applicants typically include public health agencies, nonprofit organizations, and healthcare providers with existing capacity to serve PWUD in high-impact settings.
The grant supports two components: data collection on service capacity and infectious disease testing/treatment/prevention services, and expanding access to these services. Applicants may apply for one or both components.
The funding supports activities conducted at settings that serve PWUD, such as syringe services programs, medication-assisted treatment clinics, and community health centers. Applicants should demonstrate current or planned service delivery to this population.
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Key dates
- Jul 24, 2026 Applications open
- May 24, 2027 Application deadline in 299 days
- Aug 30, 2027 Award announced
- Sep 30, 2027 Project start
Program description
This NOFO aims to strengthen services to prevent the infectious disease consequences of drug use in high impact settings serving people who use drugs (PWUD) through two components. Component 1 will improve service data by conducting a biennial survey of high-impact settings that serve PWUD to document capacity, needs, access, and service gaps. It will also improve timely local data on infectious disease consequences of drug use and the use of infectious disease testing, treatment, and prevention services at high-impact settings through a biennial biobehavioral survey of PWUD. Component 2 will increase support the availability and use of infectious disease testing, treatment and prevention services in high-impact settings serving PWUD. Applicants may apply for Component 1, Component 2, or both. Expected outcomes include enhanced capacity nationally and locally to use data to improve infectious disease testing, treatment and prevention services among PWUD, increased PWUD testing for HBV, HCV, and HIV, increased PWUD with hepatitis C who initiated treatment, and increased PWUD with HIV who engaged in care and treatment. This NOFO is in alignment with CDC priorities.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- Community Health Center
- County Government
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
Demographic focus
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (Application for Federal Assistance)
- Project narrative/work plan
- Budget and budget justification
- Organizational capacity documentation
- Data collection methodology (if applying for Component 1)
- Letters of support from partner organizations
- Evidence of current service delivery or development plan
Program contact
- 👤 Monica Adams
- 📧 ydy7@cdc.gov
- 📞 404-718-5092
Funding track record
Recent awards under CFDA 93.488 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$38,143,639
-
$5,325,663
-
$4,303,665
-
$4,257,993
-
$4,154,664
-
$4,077,516
-
$3,625,451
-
$3,594,829
-
$3,564,078
-
$2,836,208
Top States by Funding
- DC 3 awards $45.2M
- CA 3 awards $10.5M
- WA 2 awards $9.5M
- NY 2 awards $6.0M
- NC 1 awards $4.1M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.488). How funding has trended year over year.
| 2024 | $12,360,821 | |
| 2025 | $12,460,101 | |
| 2026 est. | $12,460,101 |
FAQ
Who can apply for this grant?
Public health agencies, nonprofits, and healthcare providers serving people who use drugs in high-impact settings. Your organization should have capacity to serve PWUD or be developing such capacity.
What does this grant fund?
Two components: conducting biennial surveys of services and PWUD health behaviors, and expanding infectious disease testing, treatment, and prevention services. You may apply for one or both components.
Are there deadlines or timing restrictions?
The deadline is May 24, 2027. This is a fixed deadline, not rolling. Check for any notices of intent or pre-application requirements.
What makes a competitive application?
Clear plans to collect data on service gaps and infectious disease outcomes. Strong partnerships with PWUD-serving organizations. Demonstrated ability to reach high-impact settings. Achievable targets for testing, treatment, and care engagement.
How much funding is available?
Total program funding is $82.5 million. Individual award amounts are not specified in this notice. Budget your request based on your proposed scope and service area.
💡 Tips for applicants
- Partner with established syringe services programs, treatment providers, and community organizations. Strong partnerships strengthen data collection and service expansion efforts.
- Align your proposal with CDC infectious disease priorities: HBV, HCV, and HIV testing, treatment initiation, and care engagement among PWUD.
- Use existing local data or epidemiological reports. Show how your program will fill specific service gaps you've identified.
- Plan realistic timelines for biennial surveys and service implementation. Clear, measurable targets for testing and treatment numbers strengthen competitiveness.
- Address equity and accessibility throughout. Explain how you'll reach underserved or marginalized PWUD populations in your service area.
⚠️ Common mistakes
Weak partnerships with PWUD-serving organizations or unclear service delivery capacity. Vague goals that don't tie to CDC infectious disease priorities or lack specific numerical targets. Insufficient attention to stigma, trust, and the unique needs of people who use drugs in your service setting.
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