Interventions on Health and Healthcare Disparities on Non-Communicable and Chronic Diseases in Latin America: Improving Health Outcomes Across the Hemisphere (R01 – Clinical Trial Required)
Can you apply?
This grant is for researchers studying health disparities and non-communicable diseases in Latin America. Applicants must have access to Latin American clinical sites and capacity to conduct a clinical trial. Domestic and foreign institutions eligible. U.S. citizenship/permanent residency required for key personnel. Active clinical research infrastructure and IRB approval needed.
Eligible organizations include academic medical centers, research institutions, and health organizations with established Latin American partnerships. Funding supports research design, data collection, and participant recruitment. International collaboration strongly encouraged.
Budget varies but typically supports multi-year research. Applications require detailed clinical trial protocols and clear health equity frameworks. Strong track record in Latin American health research is competitive advantage.
This grant is for researchers studying health disparities and non-communicable diseases in Latin America. Applicants must have access to Latin American clinical sites and capacity to conduct a clinical trial. Domestic and foreign institutions eligible. U.S. citizenship/permanent residency required for key personnel. Active clinical research infrastructure and IRB approval needed.
Eligible organizations include academic medical centers, research institutions, and health organizations with established Latin American partnerships. Funding supports research design, data collection, and participant recruitment. International collaboration strongly encouraged.
Budget varies but typically supports multi-year research. Applications require detailed clinical trial protocols and clear health equity frameworks. Strong track record in Latin American health research is competitive advantage.
Program description
The purpose of this Notice of Funding Opportunity (NOFO) is to support innovative and interdisciplinary research teams focused on clinical, health services, and/or community-based interventions that address health and healthcare disparities related to non-communicable and chronic diseases (NCDs) with the highest burden and mortality in Latin America and among U.S. Hispanics/Latinos. Multidisciplinary research teams would be expected to meaningfully collaborate with key partners that must include at least one PI or MPI from institutions in Latin America.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- Community Health Center
- County Government
- Hospital
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
Demographic focus
Details
This grant is for researchers studying health disparities and non-communicable diseases in Latin America. Applicants must have access to Latin American clinical sites and capacity to conduct a clinical trial. Domestic and foreign institutions eligible. U.S. citizenship/permanent residency required for key personnel. Active clinical research infrastructure and IRB approval needed.
Eligible organizations include academic medical centers, research institutions, and health organizations with established Latin American partnerships. Funding supports research design, data collection, and participant recruitment. International collaboration strongly encouraged.
Budget varies but typically supports multi-year research. Applications require detailed clinical trial protocols and clear health equity frameworks. Strong track record in Latin American health research is competitive advantage.
How to apply
Application links
Required documents
- SF-424 (R&R)
- Project Narrative (research aims, methods, significance)
- Clinical Trial Protocol
- Detailed Budget and Justification
- Biosketches of all key personnel
- Letters of Support/Collaboration from Latin American sites
- Human Subjects Protection documentation
- Preliminary Data/Publications
- Facilities and Resources description
Program contact
- 👤 National Institutes of Health
- 📧 grantsinfo@nih.gov
- 📞 301-402-2541
Funding track record
Recent awards under CFDA 93.313 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$5,096,612
-
$2,994,561
-
$2,736,581
-
$2,735,186
-
$2,417,324
-
$1,332,345
-
$1,108,110
Top States by Funding
- TX 1 awards $5.1M
- GA 1 awards $3.0M
- NC 1 awards $2.7M
- MD 1 awards $2.7M
- MI 1 awards $2.4M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.313). How funding has trended year over year.
| 2024 | $48,892,335 | |
| 2025 | $54,230,732 | |
| 2026 est. | $52,202,393 |
FAQ
Who can apply for this grant?
Academic medical centers, research institutions, and health organizations with clinical trial capacity. U.S. citizenship or permanent residency required for project director/principal investigator.
What geographic scope applies?
Research must be conducted in Latin American countries. Domestic institutions can serve as awardees with international sites as partners.
Are clinical trials really required?
Yes. A clinical trial component is mandatory for this R01 mechanism. Trial design must address health disparities.
How competitive is this funding?
Very competitive. NIH R01 success rates typically 20-25%. Strong preliminary data and Latin American partnerships increase competitiveness.
What is the typical funding range?
Usually $200,000-$500,000 annual award over 3-5 years, though amounts vary by project scope and complexity.
💡 Tips for applicants
- Establish Latin American partnerships early. Letters of collaboration from clinical sites strengthen applications significantly.
- Pilot data addressing your specific research question is critical. Unfunded pilot studies show feasibility to reviewers.
- Frame disparities clearly. Explain why this disease burden exists and how your trial reduces specific gaps in the population studied.
- Build a diverse research team. Include local investigators and community partners from target countries.
- Budget for regulatory/ethical compliance carefully. IRB approvals, regulatory permits, and community engagement require advance planning and funding.
⚠️ Common mistakes
Weak Latin American partnerships or unclear roles of local collaborators. Reviewers expect genuine co-investigation, not just data collection sites.
Insufficient justification for why Latin America is the right setting. Applications must show regional disease burden data and existing research gaps.
Clinical trial design that doesn't address health disparities. The mechanism requires explicit connection between trial outcomes and reducing inequality.
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