Improving regional capacity to respond to HIV, TB, and other global health priorities in Central America
Can you apply?
This grant is for organizations responding to HIV, TB, and global health priorities in Central America. Eligible applicants must have capacity to work in El Salvador, Guatemala, Honduras, Nicaragua, and Panama. The program supports prevention, diagnosis, and treatment activities. Projects should facilitate country ownership and build local healthcare capacity through direct engagement with government health systems.
Key dates
- Oct 1, 2025 Applications open
- Jun 19, 2026 Application deadline in 18 days
- Jan 1, 2027 Award announced
- Jan 1, 2027 Project start
This grant is for organizations responding to HIV, TB, and global health priorities in Central America. Eligible applicants must have capacity to work in El Salvador, Guatemala, Honduras, Nicaragua, and Panama. The program supports prevention, diagnosis, and treatment activities. Projects should facilitate country ownership and build local healthcare capacity through direct engagement with government health systems.
Program description
The Award Ceiling for Year 1 is 0 (none). CDC anticipates an Approximate Total Fiscal Year Funding amount of $20,000,000 for Year 1, subject to the availability of funds.
You will advance progress towards achieving the 95-95-95 targets and continue to transition site-level support to local governments in Central America (CA) for:
- El Salvador.
- Guatemala.
- Honduras.
- Nicaragua.
- Panama.
To achieve the goals of this NOFO, you will address gaps in:
- HIV prevention.
- Diagnosis.
- Life-saving treatment.
Proposed activities should facilitate country ownership while improving local capacity to:
- Make sure HIV prevention is available for populations most at risk, through the Sentinel Surveillance of STI and HIV Strategy (VICITS).
- Provide testing that leads to active linkage to HIV treatment and prevention services.
- Improve early HIV diagnosis through active case-finding strategies, including:
- Testing as outreach for populations most at risk for HIV.
- Index, provider-initiated, and community testing.
- Social network strategy.
- Self-testing.
- Support the integration of comprehensive care and treatment services, including for HIV, TB, and other opportunistic infections.
- Build capacity of healthcare workers to provide high-quality health services led by the country, and through continuous quality improvement (CQI) initiatives.
- Make sure adequate data systems are used to monitor progress toward 95-95-95 targets and other global health priorities.
- Support sustainable health systems that improve:
- Efficiency.
- Country ownership of the program.
- Global health security to fight priority infectious diseases and other public health threats.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- County Government
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
Details
This grant is for organizations responding to HIV, TB, and global health priorities in Central America. Eligible applicants must have capacity to work in El Salvador, Guatemala, Honduras, Nicaragua, and Panama. The program supports prevention, diagnosis, and treatment activities. Projects should facilitate country ownership and build local healthcare capacity through direct engagement with government health systems.
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (Application for Federal Assistance)
- Project Narrative/Statement of Work
- Budget and Budget Justification
- Organizational Background and Capacity Documentation
- Letters of Support from Central American Partners/Government Agencies
- Data Management Plan
- Monitoring and Evaluation Plan
Program contact
- 👤 DGHT NOFOs
- 📧 pepfarfoas@cdc.gov
- 📞 pepfarfoas@cdc.gov
Funding track record
Recent awards under CFDA 93.067 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$293,385,617
-
$242,496,473
-
$191,428,426
-
$78,000,027
-
$77,591,925
-
$74,485,670
-
$74,302,461
-
$64,251,263
-
$62,281,247
-
$57,879,113
Top States by Funding
- CA 2 awards $87.1M
- WA 2 awards $78.0M
- DC 1 awards $74.3M
- MD 1 awards $64.3M
- GA 1 awards $49.3M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.067). How funding has trended year over year.
| 2024 | $1,661,373,481 | |
| 2025 | $886,598,279 | |
| 2026 est. | $501,903,232 |
FAQ
Which countries are eligible for this grant?
El Salvador, Guatemala, Honduras, Nicaragua, and Panama. All activities must support these Central American nations.
What are the main funding priorities?
HIV prevention, diagnosis, and treatment services. Projects should build local capacity and support the 95-95-95 treatment targets.
What types of activities are supported?
Testing strategies, healthcare worker training, data systems, quality improvement, and TB/opportunistic infection integration. Work must transition support to local governments.
Is cost-sharing required?
No cost-sharing is required for this cooperative agreement.
What is the deadline?
The fixed deadline is June 19, 2026. Applications must arrive by this date.
💡 Tips for applicants
- Emphasize how your organization will transition support to local Central American governments over time. Country ownership is critical.
- Connect all proposed activities to progress toward the 95-95-95 HIV treatment targets. Be specific about outcomes.
- Highlight partnerships with host country health ministries and existing relationships in your target country.
- Include clear workforce capacity-building activities. Strengthening local healthcare worker skills is a priority.
- Develop a data monitoring plan showing how you will track progress on HIV prevention, diagnosis, and treatment metrics.
⚠️ Common mistakes
Failing to address country ownership and transition planning. Applications must clearly show how local governments will eventually lead the work.
Proposing activities without clear connection to the 95-95-95 targets. Reviewers expect specific, measurable progress toward these global benchmarks.
Underestimating the importance of healthcare worker capacity-building. Training and quality improvement initiatives must be central, not peripheral.
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