21st Century Cures Act: Regenerative Medicine Initiative

Regenerative Medicine Initiative
CFDA 93.370 Active Project Grants (Cooperative Agreements)

Program Funding

Annual program obligations reported to SAM.gov.

Latest annual funding (estimated)
$1.5M FY2025
$2M
FY17
$4M
FY19
$3.1M
FY20
$2.6M
FY21
$2M
FY22
$4.7M
FY23
$4.6M
FY24*
$1.5M
FY25*
* estimated

Program Objective

To provide support for initiatives funded under the 21st Century Cures Act to support the BRAIN Initiative’s aim of revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies, researchers will be able to produce a revolutionary new dynamic picture of the brain that, for the first time, shows how individual cells and complex neural circuits interact in both time and space. Long desired by researchers seeking new ways to treat, cure, and even prevent brain disorders, this picture will fill major gaps in our current knowledge and provide unprecedented opportunities for exploring exactly how the brain enables the human body to record, process, utilize,

Eligibility

Eligible Applicants

  • Public nonprofits
  • Other public organizations

The awardee will be a university, college, hospital, public agency, nonprofit research institution or for-profit organization that applies and receives a grant for support of research by a named principal investigator. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council.

Beneficiaries

  • 7
  • 8

Any nonprofit or for-profit organization, company, or institution engaged in biomedical research.

How to Apply

Award Procedure

Grants and cooperative agreements are funded based on scientific merit, program relevance, and program balance and are made annually. The initial grant award provides funds for the first budget period (usually 12 months) and letter Notice of Award indicates support recommended for the remainder of the project period, allocation of Federal funds by budget categories and special conditions, if any.

Regular Grants: Approximately 10 months

Program details & compliance

Use of Funds

Allowed Uses

Grants and cooperative agreements may be made to eligible institutions for the support of the BRAIN Initiative. The grants and cooperative agreements may be used for personnel, consultant costs, equipment, supplies, travel, patient costs, animals, alterations and renovations, miscellaneous items, and Facilities and Administrative Costs (formerly known as indirect costs).

Required Documentation

Applications must be submitted in compliance with instructions provided with each initiative.

Reporting & Compliance

Applicable 2 CFR 200 Subparts

  • Subpart B — General Provisions
  • Subpart C — Pre-Federal Award Requirements
  • Subpart D — Post-Federal Award Requirements
  • Subpart E — Cost Principles
  • Subpart F — Audit Requirements

Contacts

Dana A. Phares
301 827-7968
National Institutes of Health 6701 Rockledge Drive, Room 7176, Bethesda, MD 20832
Data from SAM.gov Federal Assistance Listings. Source published: 2024-11-12. Spec v1.0. Last synced: 2026-06-02 02:42:35.