21st Century Cures Act – Beau Biden Cancer Moonshot

moonshot
CFDA 93.353 Active Grant Cooperative Agreement

Program Funding

Annual program obligations reported to SAM.gov.

Latest annual funding
$109.5M FY2025
$67.9M
FY24
$109.5M
FY25

Funded Projects

Examples of what this program has supported.

FY2025 FY2025 actual awards made was 64.
FY2026 FY2026 estimated total awards to be made is 0.

Program Objective

To provide support for initiatives funded under the 21st Century Cures Act to support cancer research, such as the development of cancer vaccines, the development of more sensitive diagnostic tests for cancer, immunotherapy and the development of combination therapies, and research that has the potential to transform the scientific field, that has inherently higher risk, and that seeks to address major challenges related to cancer.

Eligibility

Eligible Applicants

  • Local
  • State
  • Territorial
  • Tribal
  • Nonprofit Organization
  • Not-for-Profit Organization
  • For-Profit Organization

The awardee will be a university, college, hospital, public agency, nonprofit research institution or for-profit organization that applies and receives a grant for support of research by a named principal investigator. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council.

How to Apply

Award Procedure

All applications are evaluated by scientific authorities for scientific and technical merit. Applications must also be reviewed by the National Cancer Advisory Board. All competitive applications compete for available funds on the basis of scientific and technical merit, program relevance, and program balance, consistent with NCI and NIH priorities and strategic plans.

Decision Timeline

  • Renewal interval: From 30 to 60 days
  • Appeal: From 15 to 30 days

Regular Grants: Approximately 10 months

Program details & compliance

Description

To provide support for initiatives funded under the 21st Century Cures Act to support cancer research, such as the development of cancer vaccines, the development of more sensitive diagnostic tests for cancer, immunotherapy and the development of combination therapies, and research that has the potential to transform the scientific field, that has inherently higher risk, and that seeks to address major challenges related to cancer.

Mission Categories

Primary: General Health and Medical

Other categories:
Research and DevelopmentBiology

Use of Funds

Allowed Uses

Grants and cooperative agreements may be made to eligible institutions for the support of cancer research projects. The grants and cooperative agreements may be used for personnel, consultant costs, equipment, supplies, travel, patient costs, animals, alterations and renovations, miscellaneous items, and Facilities and Administrative Costs (formerly known as indirect costs).

Required Documentation

Applications must be submitted in compliance with instructions provided with each initiative.

Reporting & Compliance

Audit Required
Yes — Annual
Records Retention
3 years

Applicable 2 CFR 200 Subparts

  • Subpart B — General Provisions
  • Subpart C — Pre-Federal Award Requirements
  • Subpart D — Post-Federal Award Requirements
  • Subpart E — Cost Principles
  • Subpart F — Audit Requirements

Contacts

Paul Gallourakis
240-276-6437
9609 Medical Center Dr, Rockville, MD 20850
Scott Chen, PhD
240-276-6038
9609 Medical Center Dr, Rockville, MD 20850
Data from SAM.gov Federal Assistance Listings. Source published: 2026-02-09. Spec v2.0. Last synced: 2026-05-28 07:29:10.