Advancing Global Health
🏛 Bureau of Global Health Security and Diplomacy (DOS-GHSD)
✓ Free, no account · Source: Grants.gov · Last verified Oct 8, 2026
Can you apply?
This grant is for organizations working to strengthen global health systems and advance U.S. global health priorities. Eligible applicants must be identified through an Annual Program Statement (APS) and align with bilateral Memoranda of Understanding (MOUs). Specific eligibility criteria are established through Addenda posted by the Department of State's Global Health Security and Diplomacy bureau, which outline targeted health challenges and priorities in partnership with U.S. Embassies. Activities must complement existing implementation efforts and address identified gaps in health system strengthening, self-reliance, and cost efficiency.
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Program description
The Department of State invites eligible applicants to advance the America First Global Health Strategy, which aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U.S. investments benefit American safety, strength, and prosperity. This Annual Program Statement (APS) establishes a supplemental framework through which the Department of State may identify and support projects that complement, extend, and/or fill identified gaps in the implementation of these bilateral MOUs. Through specific Addenda, the Department will signal priorities and needs. This APS provides the standard application instructions for the submission of all Statements of Interest (SOIs) to these specific Addenda. GHSD will collaborate with Embassies and other Department of State Bureaus and Offices to post specific funding opportunities through Addenda to this APS that address health challenges and priorities of importance.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- Statement of Interest (SOI) or application form per APS instructions
- Project narrative/proposal
- Budget and budget narrative
- Evidence of alignment with bilateral MOUs
- Partner letters of commitment
- Organization documentation (IRS 501(c)(3) or equivalent)
Program contact
- 👤 Bureau of Global Health Security and Diplomacy
- 📞 771-204-0446
Funding track record
Recent awards under CFDA 19.029 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$260,479,713
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$188,156,394
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$150,000,000
-
$128,339,677
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$75,278,121
-
$250,000
-
$219,741
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$187,000
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$180,000
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$160,000
Top States by Funding
- MD 1 awards $188.2M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 19.029). How funding has trended year over year.
| 2018 | $4,298,067 | |
| 2019 est. | $220,272 | |
| 2021 est. | $1,481,249 |
FAQ
Where do I find the specific eligibility requirements for this grant?
Check the full Annual Program Statement (APS) instructions and posted Addenda on Grants.gov. The Department of State updates priorities through Addenda that outline specific eligibility and needs.
What types of organizations can apply?
The APS instructions define eligible applicant types. Generally, State Department global health grants support nonprofits, universities, government agencies, and international organizations aligned with U.S. health diplomacy goals.
What activities does this grant support?
Funding supports projects that strengthen health systems, enhance program efficiency, build local capacity, and align with bilateral MOUs. Activities must fill gaps in existing implementation efforts.
What is the funding range for awards?
Awards range from $500,000 to $250,000,000 depending on project scope and priorities identified in specific Addenda.
Is there a fixed deadline?
Yes, the deadline is February 14, 2027. Check posted Addenda for any rolling or phased submission windows.
💡 Tips for applicants
- Review the full APS instructions carefully before drafting your proposal. The instructions contain critical eligibility details not summarized here.
- Align your project narrative with bilateral MOUs and specific Addenda priorities published by GHSD and relevant U.S. Embassies.
- Demonstrate clear outcomes in health systems strengthening, efficiency gains, and capacity building toward self-reliance.
- Build partnerships with in-country counterparts and show commitment to sustainability beyond the grant period.
- Request the appropriate funding level based on project scope—justify why your amount is necessary and realistic.
⚠️ Common mistakes
Applicants submit proposals misaligned with bilateral MOUs or current Addenda priorities. Proposals lacking clear metrics for health systems strengthening, efficiency, or self-reliance get rejected. Inadequate justification of funding needs relative to project scope undermines competitiveness.
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