ADVANCED RESEARCH PROJECTS AGENCY for HEALTH (ARPA-H)

CFDA 93.384 Active Cooperative Agreement

Program Funding

Annual program obligations reported to SAM.gov.

Latest annual funding (estimated)
$7.6M FY2026
$590.8M
FY24
$199M
FY25
$7.6M
FY26*
* estimated

Program Objective

The purpose of this program is to coordinate the acceleration of biomedical and health breakthroughs to deliver transformative, sustainable, and equitable health solutions for everyone by – (A) facilitating collaboration between Advance Research Projects Agency for Health and other Federal agencies, relevant industries, academia, and other persons, with respect to advance high-potential, high impact biomedical and health research that cannot be readily accomplished through traditional research and commercial activity; (B) identifying and promoting revolutionary advanced in health sciences; (C) promoting high reward innovation to develop high need cures (D) ensuring that the United States maintains, global leadership and science and innovation and the highest quality of life and health for its citizens.

Eligibility

Eligible Applicants

  • Unrestricted by Entity Type
  • Unrestricted by Individual Type

All types of entities are eligible, including highly qualified foreign nationals outside of the United States either alone or in collaboration with American participants when such transactions may benefit the American people. Applicants should review the Innovative Solutions Openings issued under this ARPA-H program.

Nondomestic recipients are encouraged to collaborate with a domestic entity.

Awards shall not be made to nondomestic entities organized under the laws of a covered foreign country.

Beneficiaries

  • Unrestricted by Entity Type
  • Unrestricted by Individual Type

ARPA-H is launched to conduct R&D that accelerates better health outcomes for all Americans.

How to Apply

Application Procedure

Application procedures will be posted within the applicable Innovative Solutions Opening.

Award Procedure

Discretionary awards are subject to objective review. Reviewers will individually evaluate based upon the review criteria specified in the Innovative Solutions Opening.

Decision Timeline

  • Approval: From 90 to 120 days
Program details & compliance

Description

ARPA-H shall achieve goals stated above by supporting:
Discovery, identification, and promotion of revolutionary advancements in science;
Translation of scientific discoveries into transformative health technologies with potential application for biomedical science and medicine;
Creation of platform capabilities that draw on multiple disciplines;
Delivery of proofs of concept that demonstrate meaningful advances with potential clinical application;
Development of new capabilities and methods to identify potential targets and technological strategies for early disease detection and intervention, such as advanced computational tools and predictive models; and
Acceleration of transformational health technological advances in areas with limited technical certainty.

Mission Categories

Primary: Research and Development

Use of Funds

Allowed Uses

Awards are planned to assist in ARPA-H's goal of bringing transformational health solutions to all Americans. 100% of funds are for discretionary activities.

Required Documentation

Applicants should review the individual funding opportunity announcements issued under this program for any credentials or certifications that must be submitted prior to or simultaneous with submission of an application package. 2 CFR 200, Subpart E- Cost Principles applies to this program.

Matching Requirements

Matching requirements may be included in specific solicitations.

Reporting & Compliance

Records Retention
3 years

Applicable 2 CFR 200 Subparts

  • Subpart B — General Provisions
  • Subpart C — Pre-Federal Award Requirements
  • Subpart D — Post-Federal Award Requirements
  • Subpart E — Cost Principles
  • Subpart F — Audit Requirements

Contacts

Elizabeth Fuller
2407531172
1301 K Street NW Suite 1200, Washington, DC 20005
Data from SAM.gov Federal Assistance Listings. Source published: 2026-01-20. Spec v2.0. Last synced: 2026-05-29 05:43:01.