Special Projects of Regional and National Significance
Open Opportunities (5)
Live Grants.gov opportunities funded under this program — you can apply now.
- Maternal and Child Health (MCH) Leadership, Education, and Advancement in Undergraduate Pathways (LEAP) Training Program Deadline: Jun 15, 2026 · up to $155K
- MCH Workforce Development and Training Center Deadline: Jun 15, 2026 · up to $2M
- Hereditary Hemorrhagic Telangiectasia (HHT) Center Deadline: Jun 15, 2026 · up to $2.9M
- Maternal Produce Prescription Program (MP3) Deadline: Jun 22, 2026 · up to $500K
- Regional Pediatric Prevention Network Deadline: Jun 22, 2026 · up to $11.3M
See all grants from Health Resources and Services Administration →
Program Funding
Annual program obligations reported to SAM.gov.
Who has received this funding
Organizations awarded under CFDA 93.110 (USAspending.gov).
- Zero To Three National Center For Infants, Toddlers & Families 2 awards $68,077,319
- University Hospitals Cleveland Medical Center $51,517,055
- Education Development Center, Inc. $47,831,055
- Children'S National Medical Center $37,182,998
- National Institute For Childrens Health Quality Inc $30,109,677
- Michigan Public Health Institute $20,269,976
- University Of North Carolina At Chapel Hill $16,167,482
- Acog Foundation $15,667,860
- Association Of Public Health Laboratories, Inc. (The) $14,859,999
Funded Projects
Examples of what this program has supported.
Program Objective
The Special Projects of Regional and National Significance Program (SPRANS) carries out maternal and child health (MCH) projects to support training and research; oral health integration; genetic disease testing, counseling, and information development and dissemination programs; newborn screening for sickle cell anemia and other genetic disorders; and comprehensive hemophilia diagnostic and treatment centers. The Supporting Fetal Alcohol Spectrum Disorder (FASD) Screening and Intervention helps reduce alcohol use during pregnancy and improves outcomes for children with FASD nationwide, especially in communities where there is a high rate of binge drinking during pregnancy, including rural areas and medically underserved communities. The program focuses on educating primary care providers and increasing the use of screening, intervention, and referral processes for high-risk pregnancies. The State Maternal Health Innovation program creates state-led maternal health task forces to bring together the voices of key leaders, and pregnant and postpartum individuals using state-specific maternal health data to develop and implement innovative approaches to address the most pressing maternal health needs and disparities. State approaches include strengthening partnerships and collaborations, improving state-level data surveillance on maternal mortality and severe maternal morbidity, and promoting and executing innovation in maternal health service delivery. The MCH Research Portfolio includes the MCH Research Consortium, Maternal Health Research Collaborative for Minority-Serving Institutions, MCH Research Network, and MCH Field-Initiated Innovative Research Studies programs. The research portfolio advances maternal and child health by generating and testing innovative, real-world approaches to improve population-level outcomes. The program addresses critical evidence gaps through the development of research infrastructure and the conduct of rigorous, community-engaged research in close partnership with families and other stakeholders. MCH RNs focus on collaborative, interdisciplinary. The Children’s Safety Network (CSN) purpose is to increase the capacity of Title V agencies to adopt and implement evidence-based child and adolescent safety programs, practices, and policies, with a specific focus on injury and violence-related to Title V performance and outcome measures, such as injury hospitalizations, bullying, safe sleep, and suicide, as well as leading causes of injury-related deaths among children and adolescents (e.g., motor vehicle crashes, firearms, and poisonings).
Eligibility
Eligible Applicants
- U.S. State Government
- Local
- Nonprofit Organization
- Federally Recognized Tribal Government
- Tribal Government (other)
- U.S. Territory Government
- Other
Training grants may be made to public or private nonprofit institutions of higher learning. Research grants may be made to public or private nonprofit institutions of higher learning and public or private nonprofit private agencies and organizations engaged in research or in MCH or Children with Special Health Care Needs (CSHCN) programs. Any public or private entity is eligible for hemophilia, genetics, and environmental health grants and other special project grants, including SPRANS and CISS. Eligible entities for the Supporting Fetal Alcohol Spectrum Disorders Screening and Intervention program are any domestic public or private entity, including Indian tribes or tribal organizations (as those terms are defined at 25 U.S.C. 450b). See 42 CFR § 51a.3(a), and domestic faith-based and community-based organizations. Eligible entities for the State Maternal Health Innovation program include any domestic public or private entity, including Indian tribes or tribal organizations, as well as domestic faith-based and community-based organizations. Eligible entities for the Integrated Maternal Health Services program include any domestic public or private entity, including Indian tribes or tribal organizations, as well as domestic faith-based and community-based organizations.
Beneficiaries
- Health Professional
- Infant and Toddler (0–3)
- Other
- Young Child (4–9)
Specialized group (e.g. health professionals, students, veterans), Health Professional, Student/Trainee, Women, Infant (0-5), Child (6-15)
For training grants: (1) Trainees in the health professions related to MCH; and (2) mothers and children who receive services through training programs. For research grants: public or private nonprofit agencies and organizations engaged in research in MCH or CSHCN programs. For hemophilia, sickle cell, thalassemia, genetics, newborn screening, environmental health, and other special projects: (1) Public or private agencies, organizations and institutions; and (2) mothers and children, and individuals with genetic conditions (any age) who receive services through the programs.
How to Apply
Award Procedure
All qualified applications will be forwarded to an objective review committee. Based on the recommendations of the objective review committee, the HRSA program official with delegated authority is responsible for final selection and funding decisions. Notification is made in writing by a Notice of Award.
Decision Timeline
- Approval: From 120 to 180 days
Final decisions are made 4 to 6 months after receipt of applications.
Program details & compliance
Description
The Special Projects of Regional and National Significance Program (SPRANS) carries out maternal and child health (MCH) projects to support training and research; oral health integration; genetic disease testing, counseling, and information development and dissemination programs; newborn screening for sickle cell anemia and other genetic disorders; and comprehensive hemophilia diagnostic and treatment centers. The Supporting Fetal Alcohol Spectrum Disorder (FASD) Screening and Intervention helps reduce alcohol use during pregnancy and improves outcomes for children with FASD nationwide, especially in communities where there is a high rate of binge drinking during pregnancy, including rural areas and medically underserved communities. The program focuses on educating primary care providers and increasing the use of screening, intervention, and referral processes for high-risk pregnancies. The State Maternal Health Innovation program creates state-led maternal health task forces to bring together the voices of key leaders, and pregnant and postpartum individuals using state-specific maternal health data to develop and implement innovative approaches to address the most pressing maternal health needs and disparities. State approaches include strengthening partnerships and collaborations, improving state-level data surveillance on maternal mortality and severe maternal morbidity, and promoting and executing innovation in maternal health service delivery. The MCH Research Portfolio includes the MCH Research Consortium, Maternal Health Research Collaborative for Minority-Serving Institutions, MCH Research Network, and MCH Field-Initiated Innovative Research Studies programs. The research portfolio advances maternal and child health by generating and testing innovative, real-world approaches to improve population-level outcomes. The program addresses critical evidence gaps through the development of research infrastructure and the conduct of rigorous, community-engaged research in close partnership with families and other stakeholders. MCH RNs focus on collaborative, interdisciplinary. The Children’s Safety Network (CSN) purpose is to increase the capacity of Title V agencies to adopt and implement evidence-based child and adolescent safety programs, practices, and policies, with a specific focus on injury and violence-related to Title V performance and outcome measures, such as injury hospitalizations, bullying, safe sleep, and suicide, as well as leading causes of injury-related deaths among children and adolescents (e.g., motor vehicle crashes, firearms, and poisonings).
Mission Categories
Primary: Maternity, Infants, Children
Other categories:
General Health and Medical
Use of Funds
Allowed Uses
Training grants are made to institutions of higher learning for training personnel for health care and related services for mothers and children. Research grants are for the purpose of research activities which show promise of a substantial contribution to the advancement of maternal and child health (MCH) services. Technical assistance grants support the effective and accurate use of data and evidence to support program development and implementation as well as performance measurement and evaluation. Genetic grants are for genetic disease testing, counseling and information development and dissemination. Hemophilia grants are for the support of centers which provide hemophilia diagnostic and treatment services. Sickle cell disease grants are made to support follow up for infants with sickle cell identified through newborn screening. Environmental health grants are made to decrease maternal and child morbidity and mortality associated with pre-and post-natal environmental exposures. Other special project grants are designed to support activities of a demonstration nature, which are designed to improve services for mothers and children.
Restrictions
Indirect costs that are allowed for administrative costs incurred as a result of the training grants project, are limited to 8 percent of direct costs.
Required Documentation
Applicants should review the individual HRSA notice of funding opportunity issued under this Assistance Listing for any required proof or certifications which must be submitted prior to or simultaneous with submission of an application package.
2 CFR 200, Subpart E - Cost Principles applies to this program.
Matching Requirements
Opportunities may include matching requirements. Please refer to the notice of funding opportunity.
Reporting & Compliance
Applicable 2 CFR 200 Subparts
- Subpart B — General Provisions
- Subpart C — Pre-Federal Award Requirements
- Subpart D — Post-Federal Award Requirements
- Subpart E — Cost Principles
- Subpart F — Audit Requirements