Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource (U24 Clinical Trials Optional)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 16, 2026
Can you apply?
This grant is for research institutions, universities, and medical centers seeking to continue longitudinal data analysis on adolescent alcohol use and brain development.
Eligible applicants must have expertise in neuroscience, neurodevelopment, or alcohol research. Institutions must be able to manage longitudinal cohort data and conduct rigorous statistical analysis.
This is a limited competition notice—not all applicants are eligible. NIAAA will invite specific potential collaborators aligned with NCANDA's research mission. Geographic scope is national. The grant supports continuation of existing data collection and novel analyses on participants aged 12-37.
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Key dates
- May 22, 2025 Applications open
- Aug 1, 2026 Application deadline in 15 days
- Jul 1, 2027 Award announced
- Jul 1, 2027 Project start
Program description
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) launched the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) in 2012 to determine how adolescent alcohol-related disruption of normal brain growth patterns of structure, related brain function, and psychiatric health affects brain functioning in emerging adulthood. The consortium uses an accelerated longitudinal design and has acquired data on over 800 individuals between the ages of 12 to 32 years. This wide age range covers the period before onset of drinking, the transition from adolescence to young adulthood, the critical period for binge drinking, and the time of maturing out. This unique dataset provides novel information on the enduring and transient consequences of adolescent drinking on adult brain function and behavior. Current studies on adults drinking do not have this type of data. Renewal of this limited competition NOFO will enable NCANDA to continue to follow these participants up to 37 years of age and acquire data critical to understanding how early versus late onset drinking during adolescence differentially impacts drinking behavior in adulthood. This limited competition renewal will provide valuable information for developing evidence-based alcohol prevention strategies and early intervention approaches to prevent the progression to more severe drinking and AUD thereby preventing the development of chronic disease, improving health outcomes, and increasing quality of life and longevity. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of integrative neuroscience are encouraged to begin to consider applying for this new NOFO.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (R&R) application form
- Project Narrative
- Budget and Budget Justification
- Institutional Review Board (IRB) approval or evidence of institutional commitment
- Letters of collaboration from NCANDA consortium partners
- Biosketch(es) of key personnel
- Research Plan with specific aims
Program contact
- 👤 Dominique Lorang-Leins National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- 📧 lorangd@mail.nih.gov
- 📞 301-594-6228
Funding track record
Recent awards under CFDA 93.273 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$125,900,663
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$34,675,742
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$34,469,501
-
$33,261,336
-
$32,897,567
-
$31,652,514
-
$30,394,602
-
$29,223,384
-
$29,195,978
-
$29,168,993
Top States by Funding
- CA 15 awards $242.3M
- NY 3 awards $162.6M
- OR 7 awards $96.3M
- NC 4 awards $67.1M
- IN 3 awards $57.4M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.273). How funding has trended year over year.
| 2024 | $430,377,419 | |
| 2025 | $429,906,735 | |
| 2026 est. | $12,401,560 |
FAQ
Who can apply for this limited competition grant?
NIAAA invites specific institutions with expertise in alcohol neuroscience and longitudinal research. Not all organizations may be eligible—watch for the full NOFO announcement.
When is the deadline?
The deadline is August 1, 2026. NIAAA has issued this notice early to allow time for collaboration development.
What research activities are supported?
Continuation of longitudinal follow-up of NCANDA participants and novel data analyses on alcohol's effects on adolescent brain development through age 37.
How competitive is this funding?
Very competitive. NIAAA will fund limited applications from institutions with demonstrated expertise in neurodevelopmental and alcohol research.
What is the funding range?
Total pool is $600,000. Specific award amounts per grant were not announced—details will appear in the full NOFO.
💡 Tips for applicants
- Start building or confirming research collaborations now. NIAAA prioritizes multi-institutional partnerships with complementary expertise.
- Review NCANDA's existing publications and datasets to demonstrate familiarity with the consortium's work and scientific direction.
- Emphasize novel analytical approaches or underexplored research questions not yet addressed by NCANDA's prior work.
- Ensure your institution has capacity for long-term longitudinal data management and participant follow-up through age 37.
- Plan to include specific, measurable milestones for participant retention and data quality in your project timeline.
⚠️ Common mistakes
Applying without prior engagement with NCANDA leadership or clear understanding of the consortium's existing research. Proposing analyses that duplicate prior NCANDA publications rather than offering novel insights. Underestimating the resource requirements for maintaining longitudinal follow-up of 800+ aging participants across multiple sites.
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