Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 16, 2026
Can you apply?
This grant is for institutions seeking to develop collaborative research facilities or research-resource facilities. Eligible applicants include higher education institutions, research hospitals, independent research institutes, and other nonprofit research organizations. The grant excludes clinical trials and focuses on infrastructure that supports multiuser research environments. Funding supports renovation, construction, or equipment for shared research facilities that enhance collaborative research capacity.
Not the right fit? Find grants for your organization in 5 questions →
Program description
This Notice of Funding Opportunity (NOFO) solicits applications to develop shared-use research facilities or research-supporting facilities that enable collaborative research and benefit broad research communities at large. The NOFO supports two existing construction programs: the Biomedical Research Facilities (BRF) program and the HIV/AIDS Research Facilities (HRF) program.The BRF program supports the construction or modernization of biomedical research facilities that advance basic, translational, clinical, or behavioral science research in all areas. Intended facilities include shared research spaces, core facilities, biorepositories, or other shared-use resource facilities that serve a broad scientific community with a significant, long-term impact on biomedical research.The HRF program funds the development of HIV/AIDS research or research-supporting resources that the empowered research activities must align with the NIH Office of AIDS Research (OAR) priorities, as outlined at OAR HIV/AIDS Research Priorities, including research focusing on the long-term health consequences of HIV infection.NIH encourages applications from institutions across all geographic regions of the country, including Institutions of Emerging Excellence (IEE) in biomedical research, to strengthen the nation”s research capacity.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- Colleges (all higher ed)
- County Government
- HBCU
- Hospital
- HSI (Hispanic Serving Institution)
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
How to apply
Application links
Required documents
- SF-424 (Application for Federal Assistance)
- SF-424 (R&R) Supplement
- Project Narrative and Specific Aims
- Detailed Budget and Budget Justification
- Institutional Commitment Letter
- Architectural Drawings and Facility Plans
- Equipment and Instrumentation Specifications
- Letters of Support from Users/Departments
- Organizational Capacity Documentation
- Facilities and Administrative (F&A) Cost Documentation
Program contact
- 👤 National Institutes of Health
- 📧 oripconstruction@od.nih.gov
- 📞 301-402-2541
Funding track record
Recent awards under CFDA 93.310 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$973,507,476
-
$383,462,829
-
$190,396,050
-
$179,737,926
-
$169,422,678
-
$167,922,818
-
$147,947,250
-
$143,679,156
-
$115,739,255
-
$91,722,927
Top States by Funding
- CA 3 awards $1,196.2M
- NC 4 awards $446.1M
- WA 1 awards $383.5M
- MD 2 awards $317.4M
- NY 4 awards $261.2M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.310). How funding has trended year over year.
| 2024 | $1,174,839,078 | |
| 2025 | $1,062,277,534 | |
| 2026 est. | $28,100,048 |
FAQ
Who can apply for this C06 grant?
Higher education institutions, hospitals, independent research institutes, and nonprofit research organizations are eligible. Your institution must be able to demonstrate research capability and institutional commitment.
Are clinical trials eligible for funding?
No. This grant explicitly excludes clinical trial research and facilities designed solely for clinical trial purposes.
What types of facilities can be supported?
Renovation, construction, and equipment for shared research facilities. Examples include core research centers, shared instrumentation labs, and collaborative research spaces.
What is the typical funding range?
C06 grants typically range from $500,000 to several million dollars, depending on project scope and institutional need.
When is the application deadline?
The deadline is January 25, 2028. Applications typically require 3-4 months of preparation time for institutional coordination.
💡 Tips for applicants
- Demonstrate how the facility will serve multiple research programs and investigators across your institution or consortium.
- Highlight institutional commitment through cost-sharing, letters of support, and detailed management plans.
- Include detailed architectural drawings, equipment specifications, and realistic timelines for construction or renovation.
- Show how the facility addresses a clear research need and will enhance collaborative research capacity.
- Secure strong institutional endorsement from leadership and document ongoing operational support plans.
⚠️ Common mistakes
Applications fail when multiuser benefit is unclear or cost-sharing is inadequate. Poorly defined management plans and unrealistic budgets/timelines reduce competitiveness. Applicants underestimate renovation complexity or fail to demonstrate institutional operational commitment.
Similar grants
- OPEN Modern Equipment for Shared-use Biomedical Research Facilities: Advancing Research-Related Operations (S15 Clinical Trial Not Allowed) — National Institutes of Health
- OPEN Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required) — National Institutes of Health
- OPEN NIAID Resource-Related Research Projects (R24 Clinical Trial Not Allowed) — National Institutes of Health
- CLOSED Limited Competition: Community-Partnered Nursing Research Centers for Schools and Colleges of Nursing with Limited NIH Funding (P20 Clinical Trial Optional) — National Institutes of Health
- OPEN National Biomedical Research Centers (P50 Clinical Trial Optional) — National Institutes of Health