Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement Clinical Trial Optional)
Can you apply?
This grant is for researchers holding existing NIH grants or cooperative agreements who need urgent funding for critical changes. Eligible applicants include institutions with active NIH funding for research programs. The supplement supports competitive revisions to ongoing research projects. Clinical trials are optional components. Applications must address time-sensitive needs that impact the existing project's success or continuation.
Supplemental funding requires justification of urgency and how the additional funds extend or improve the current research. Research institutions, universities, and affiliated research organizations with current NIH awards may apply. The revision must strengthen the original project without fundamentally changing its scope.
Key dates
- Mar 4, 2026 Applications open
- Jun 1, 2026 Application deadline today
- Jul 1, 2026 Award announced
- Jul 1, 2026 Project start
This grant is for researchers holding existing NIH grants or cooperative agreements who need urgent funding for critical changes. Eligible applicants include institutions with active NIH funding for research programs. The supplement supports competitive revisions to ongoing research projects. Clinical trials are optional components. Applications must address time-sensitive needs that impact the existing project's success or continuation.
Supplemental funding requires justification of urgency and how the additional funds extend or improve the current research. Research institutions, universities, and affiliated research organizations with current NIH awards may apply. The revision must strengthen the original project without fundamentally changing its scope.
Program description
The National Institutes of Health (NIH) intends to issue a Notice of Funding opportunity to allow applications for competitive revisions of ongoing grants to address specific public health crises that were unforeseen when the original application was submitted. Once this Notice of Funding Opportunity (NOFO) is approved and issued, applications for Urgent Competitive Revisions will be routed directly to the NIH awarding component listed on the Notice of Award of the most recent parent award.
Only applications submitted in response to an Urgent Guide Notice published by an IC will be allowed to apply to the NOFO once it’s published.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- County Government
- Hospital
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
Details
This grant is for researchers holding existing NIH grants or cooperative agreements who need urgent funding for critical changes. Eligible applicants include institutions with active NIH funding for research programs. The supplement supports competitive revisions to ongoing research projects. Clinical trials are optional components. Applications must address time-sensitive needs that impact the existing project's success or continuation.
Supplemental funding requires justification of urgency and how the additional funds extend or improve the current research. Research institutions, universities, and affiliated research organizations with current NIH awards may apply. The revision must strengthen the original project without fundamentally changing its scope.
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (Application for Federal Assistance)
- Project Narrative (revision description and scientific justification)
- Budget and Budget Justification
- Biosketch for key personnel (if new staff added)
- Current/recent progress report from original award
Program contact
- 👤 Division of Grants Policy (DGP), Office of Policy for Extramural Research Administration (OPERA)
- 📧 GrantsPolicy@od.nih.gov
- 📞 Please contact via email.
Funding track record
Recent awards under CFDA 93.310 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$973,507,476
-
$383,462,829
-
$190,396,050
-
$179,743,190
-
$169,422,678
-
$167,922,818
-
$143,679,156
-
$134,358,531
-
$115,739,255
-
$91,722,927
Top States by Funding
- NC 5 awards $1,419.5M
- WA 1 awards $383.5M
- MD 2 awards $303.8M
- NY 3 awards $192.1M
- NJ 1 awards $179.7M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.310). How funding has trended year over year.
| 2024 | $1,174,839,078 | |
| 2025 | $1,062,277,534 | |
| 2026 est. | $28,100,048 |
FAQ
Who is eligible to apply for this supplement?
Only investigators with existing active NIH grants or cooperative agreements can apply. Your institution must be in good standing with NIH.
What types of research does this supplement support?
Clinical trial work and other research needing urgent revisions to active projects. The supplement must directly support the existing award's objectives.
What makes an application competitive?
Clear justification of urgency. Strong scientific rationale for the revision. Demonstration that additional funds significantly advance the original project.
Are there funding limits?
Supplement budgets vary by institute and original award level. Budget narrative must explain all requested costs.
Can I use this for a brand new research direction?
No. The supplement must support revisions to the existing project, not new research topics.
💡 Tips for applicants
- Start by clearly defining what has changed since your original award. Why do you need the supplement now?
- Tie every proposed activity directly to your existing NIH grant aims. Show continuity, not new directions.
- If including a clinical trial component, ensure it aligns with your original project scope and timelines.
- Contact your NIH program officer before submitting. They can advise on feasibility and budget expectations.
- Keep your narrative concise and focused on the urgent need. Reviewers evaluate supplements quickly.
⚠️ Common mistakes
Requesting funds for unrelated new research instead of revisions to the existing project. Failing to justify true urgency or time sensitivity. Submitting without pre-award notification to your NIH program officer.
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