Sickle Cell Disease Regional Care Excellence (SoRCE) Program
Can you apply?
This grant is for healthcare organizations and programs serving patients with sickle cell disease. Eligible applicants include federally qualified health centers (FQHCs), hospitals, academic medical centers, and nonprofit healthcare organizations. The program supports regional care networks that improve sickle cell disease management and outcomes.
Applicants must demonstrate capacity to serve sickle cell patients and coordinate multidisciplinary care. Organizations must be located in the United States and meet applicable 501(c)(3) or public entity requirements.
The program funds development of regional care excellence centers. Activities include establishing coordinated care systems, training healthcare providers, and improving patient access to specialized sickle cell services.
Key dates
- Dec 11, 2025 Applications open
- Jun 15, 2026 Application deadline in 14 days
- Aug 1, 2026 Award announced
- Sep 1, 2026 Project start
This grant is for healthcare organizations and programs serving patients with sickle cell disease. Eligible applicants include federally qualified health centers (FQHCs), hospitals, academic medical centers, and nonprofit healthcare organizations. The program supports regional care networks that improve sickle cell disease management and outcomes.
Applicants must demonstrate capacity to serve sickle cell patients and coordinate multidisciplinary care. Organizations must be located in the United States and meet applicable 501(c)(3) or public entity requirements.
The program funds development of regional care excellence centers. Activities include establishing coordinated care systems, training healthcare providers, and improving patient access to specialized sickle cell services.
Program description
Sickle Cell Disease Regional Care Excellence Program (SoRCE) is to improve the health of people with sickle cell disease (SCD) by expanding access to care, improving the quality of care, and tracking quality of life indicators. There are approximately 100,000 people in the United States with SCD. Treatment starting in early childhood can prevent or reduce complications such as severe pain episodes, silent strokes, and premature death. Despite universal identification at birth, fewer than half of children with SCD receive needed treatment. As these children become adolescents and transition to adulthood many are not appropriately identified as candidates for disease-modifying therapies, in part because their doctors are still learning how to use the latest treatments. The program is made up of seven regions with one award recipient per region serving as a Regional Coordinating Hub (RCH). Each award recipient will work with clinical and community-based partners in their region and engage in continuous quality improvement (CQI) initiatives to improve access and quality of care.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- Community Health Center
- FQHC (Federally Qualified Health Center)
- Hospital
- Nonprofits
- Private University
- Public University
Demographic focus
Details
This grant is for healthcare organizations and programs serving patients with sickle cell disease. Eligible applicants include federally qualified health centers (FQHCs), hospitals, academic medical centers, and nonprofit healthcare organizations. The program supports regional care networks that improve sickle cell disease management and outcomes.
Applicants must demonstrate capacity to serve sickle cell patients and coordinate multidisciplinary care. Organizations must be located in the United States and meet applicable 501(c)(3) or public entity requirements.
The program funds development of regional care excellence centers. Activities include establishing coordinated care systems, training healthcare providers, and improving patient access to specialized sickle cell services.
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (Application for Federal Assistance)
- Project Narrative describing regional care network plan
- Budget and Budget Narrative
- Organizational capacity documentation
- Letters of support from partner organizations
- Evidence of sickle cell patient population served
- Key personnel CVs and job descriptions
Program contact
- 👤 MCHB
- 📧 scdprograms@hrsa.gov
- 📞 240-438-6795
Funding track record
Recent awards under CFDA 93.365 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$8,565,453
-
$6,266,000
-
$6,265,971
-
$6,219,000
-
$5,908,498
-
$2,037,715
Top States by Funding
- MD 1 awards $8.6M
- OH 1 awards $6.3M
- MO 1 awards $6.3M
- AL 1 awards $6.2M
- CA 1 awards $5.9M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.365). How funding has trended year over year.
| 2024 | $5,620,000 | |
| 2025 | $5,775,000 | |
| 2026 est. | $6,650,000 |
FAQ
Who can apply for SoRCE funding?
Federally qualified health centers, hospitals, medical centers, and nonprofit healthcare organizations can apply. Your organization should serve sickle cell patients and have capacity to coordinate regional care networks.
What is the application deadline?
Check the HRSA website or grants.gov for the current deadline, as it was not specified in available materials. Funding typically opens annually for new applications.
What activities does SoRCE support?
The program funds development of regional care networks, provider training, care coordination systems, and improved access to sickle cell disease specialty services.
How competitive is this grant?
This is a moderate to highly competitive federal program. Applicants with established healthcare infrastructure and sickle cell expertise have stronger proposals.
What is the typical funding range?
Grants typically range from several hundred thousand to over one million dollars. Check recent HRSA announcements for current award amounts.
💡 Tips for applicants
- Connect your proposal to regional gaps in sickle cell care. Show why your service area needs better coordination and services.
- Highlight partnerships with multiple healthcare providers and patient organizations. Collaboration strengthens your regional care network approach.
- Include data on your patient population, current outcomes, and barriers they face. Evidence of need increases competitiveness.
- Demonstrate staff expertise in sickle cell disease and healthcare program management. Include CVs of key personnel.
- Address sustainability beyond the grant period. Show how you will maintain services and systems after federal funding ends.
⚠️ Common mistakes
Proposing care improvements without showing regional partnerships or coordination. SoRCE requires multidisciplinary networks, not isolated programs.
Underestimating provider training and infrastructure costs. Developing excellence centers requires significant investment in staff development and systems.
Failing to include concrete patient outcome metrics. Applications need specific, measurable goals for sickle cell disease management improvements.
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