OPEN CFDA 93.103 ↗ Competitive Cooperative Agreement Competitive ~100h typical effort

Research, Education, and Outreach on Botanical Natural Products

🏛 Food and Drug Administration (HHS-FDA)

✓ Free, no account · Source: Grants.gov · Last verified Jul 27, 2026

⏰ Deadline
Aug 21, 2026 in 23 days
💰 Award amount
up to $5.1M
🎯 Expected awards
1 recipient
📍 Scope
National

Can you apply?

This grant is for botanical natural products research, education, and outreach in collaboration with the FDA. Only the University of Mississippi is eligible to apply. The program supports identification and validation of botanical ingredients in foods, dietary supplements, and cosmetics. Activities include developing reference materials, exchanging scientific information with FDA, and coordinating workshops on botanical topics relevant to public health.

The funding focuses on safety assessment of botanical products. Eligible work includes acquiring authenticated plant materials and purified natural products. Collaboration with FDA scientists in mutual research areas is expected.

Eligible applicants
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Program description

The purpose of this funding opportunity is to provide continued support to: (1) assist in the identification and development of a prioritized list of botanical ingredients based on safety concerns, trends and knowledge of botanical ingredients in foods, dietary supplements, and cosmetics marketed in the U.S.; (2) acquire, validate and characterize authenticated reference materials, including raw and processed plant materials and purified natural products of relevance to FDA for evaluation of safety; (3) exchange technical and scientific information, methods and reference material with FDA scientists and other stakeholders; (4) collaborate with FDA scientists in research areas of mutual interest; (5) coordinate scientific workshops, training and conferences on botanical topics of public health relevance to address high priority science and research needs. 

Who can apply

Eligible applicants

How to apply

Application links

Key dates & requirements

  • 📄 Narrative page limit: 30 pages
  • Project period: 60 months
  • 🧾 Budget narrative required. Free budget template →

Required documents

  • SF-424 Federal Grant Application
  • Project Narrative with research plan
  • Budget and Budget Justification
  • Letters of Support from FDA collaborators
  • Curriculum Vitae for Key Personnel
  • Institutional Commitment Letter

Program contact

Funding track record

Recent awards under CFDA 93.103 from the last 3 years — real organizations that won funding through this same program.

104
awards (3 yrs)
$1.0B
total funded
75
unique recipients
$10.1M
average award

Top 10 Largest Recent Awards

  1. $121,795,918
  2. $76,105,626
  3. $50,217,964
  4. $47,940,304
  5. $36,000,000
  6. $35,573,997
  7. $35,391,995
  8. $30,732,300
  9. $24,423,552
  10. $23,332,999

Top States by Funding

  • AZ 4 awards $134.7M
  • CA 9 awards $111.3M
  • MD 7 awards $108.8M
  • VA 5 awards $96.6M
  • PA 10 awards $77.4M

Source: USAspending.gov — federal spending transparency. Data covers last 3 years.

Funding history

Annual funding for this program — Federal obligations (CFDA 93.103). How funding has trended year over year.

2016 $170,482,435
2017 est. $208,900,832
2018 $173,077,408
2019 $198,507,896
2020 $212,448,590
2021 $218,918,739
2022 est. $255,910,458
2023 est. $246,894,600

FAQ

Who can apply for this grant?

Only the University of Mississippi is eligible. This is a single-source funding opportunity restricted to this institution.

What activities are supported?

The grant supports botanical ingredient identification, development of reference materials, research collaboration with FDA scientists, and scientific workshops on botanical safety topics.

Is there a deadline?

Yes, the deadline is August 21, 2026. This is a fixed deadline, not rolling.

What is the funding amount?

The award can reach up to $5,100,000. Specific amounts vary based on project scope and FDA priorities.

Is cost-sharing required?

No, cost-sharing is not required for this grant. All eligible project costs can be covered by the award.

💡 Tips for applicants

  • Focus on collaborative research areas with FDA scientists. Alignment with agency priorities increases competitiveness significantly.
  • Develop detailed plans for acquiring and validating botanical reference materials. These materials are central to the grant's goals.
  • Emphasize public health relevance in your research. The FDA prioritizes work addressing safety concerns in foods and supplements.
  • Plan clear dissemination through workshops, training, and conferences. The grant values scientific knowledge sharing with stakeholders.
  • Build strong partnerships with FDA collaborators before submitting. Pre-existing relationships demonstrate feasibility and commitment.

⚠️ Common mistakes

Applicants fail to establish prior collaboration with FDA scientists, which signals low likelihood of productive partnership. Proposals lack clear reference material validation protocols or authentication methods for botanical samples. Projects that emphasize basic research over public health impact miss the FDA's mission-driven focus.

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