Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 15, 2026
Can you apply?
This grant is for translating basic hearing, balance, and speech/language research into clinical practice. Domestic nonprofit organizations, educational institutions, and government agencies can apply. Individual researchers with institutional affiliation may be eligible. Applications must include feasibility data and a path toward clinical application.
Research must address hearing loss, balance disorders, speech-language pathology, or related areas. U.S.-based institutions are prioritized, though foreign organizations may qualify under specific conditions.
Proposed studies should demonstrate translational potential. Clinical trials are optional but strengthen competitiveness. Preliminary data supporting the research question is typically required.
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Program description
This Funding Opportunity Announcement (FOA) is intended to provide an avenue for basic scientists, clinicians and clinical scientists to jointly initiate and conduct translational research projects which translate basic research findings into clinical tools for better human health. The scope of this FOA includes a range of activities to encourage translation of basic research findings which will impact the diagnosis, treatment and prevention of communication disorders. Connection to the clinical condition must be clearly established and the outcomes of the grant must have practical clinical impact.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- Colleges (all higher ed)
- County Government
- Hospital
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Researcher (independent)
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
How to apply
Application links
Required documents
- SF-424 (R&R) Application Form
- Research Plan (Specific Aims, Significance, Innovation, Approach)
- Preliminary Studies and Progress Report
- Budget and Budget Justification
- Biographical Sketches (NIH Form)
- Supporting Letters of Commitment
- Institutional Review Board (IRB) Approval documentation if applicable
Program contact
- 👤 National Institutes of Health
- 📧 grantsinfo@nih.gov
- 📞 301-402-2541
Funding track record
Recent awards under CFDA 93.173 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$67,501,043
-
$41,811,330
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$29,666,573
-
$25,009,162
-
$22,883,624
-
$22,740,456
-
$16,596,227
-
$13,760,149
-
$12,363,350
-
$12,276,804
Top States by Funding
- MA 11 awards $143.1M
- CA 10 awards $101.6M
- IA 5 awards $77.5M
- CT 2 awards $76.3M
- MD 8 awards $65.0M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.173). How funding has trended year over year.
| 2024 | $422,034,489 | |
| 2025 | $422,700,014 | |
| 2026 est. | $427,030,000 |
FAQ
Who is eligible to apply?
Nonprofit organizations, universities, hospitals, and government agencies with a domestic base. Individual researchers must have institutional affiliation and support.
What should the research focus on?
Translating basic research into clinical practice for hearing, balance, speech-language, or related conditions. Studies must show clear clinical relevance and feasibility.
Is preliminary data required?
Yes. Applicants need preliminary results demonstrating feasibility and supporting the research question.
How competitive are these grants?
Highly competitive. Success typically requires strong preliminary data, clear translational pathway, and experienced research team.
What is the typical funding range?
R01 grants typically range $200,000 to $500,000 per year, though actual awards vary by study complexity and reviewer assessment.
💡 Tips for applicants
- Show a clear path from bench research to patient benefit. Reviewers want translational feasibility, not basic science alone.
- Include strong preliminary data. Weak preliminary results are a common reason for rejection.
- Define clinical endpoints clearly. Explain how findings will change diagnosis or treatment in real patients.
- Build a strong team. Include collaborators with clinical expertise and translational experience.
- Address feasibility upfront. Describe recruitment, timeline, and specific clinical trial methods if applicable.
⚠️ Common mistakes
Weak or absent preliminary data suggesting study feasibility. Lack of clear clinical application or patient benefit pathway. Poor team composition missing clinical or industry partners with translational experience.
Similar grants
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- OPEN Early-Stage Dissemination and Implementation Research in Communication Disorders (R21 Clinical Trial Optional) — National Institutes of Health
- OPEN Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) — National Institutes of Health
- OPEN Advancement and Innovation in Measurement of Language Development and Predictors (R01 Clinical Trial Not Allowed) — National Institutes of Health
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