Project: Omics Phenotypes Related to Down Syndrome (X01 Clinical Trial Not Allowed)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 28, 2026
Can you apply?
This grant is for researchers submitting existing biospecimens from individuals with Down syndrome and controls to NIH INCLUDE Project-supported resources.
Eligible applicants include academic institutions, research organizations, and other entities that have collected biosamples. Applicants must propose omics assays on existing biospecimens, not generate new funding for data collection.
Researchers will provide samples and data to the INCLUDE Data Hub for sharing with the broader research community. No direct funding is awarded to applicants.
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Key dates
- Jul 28, 2026 Applications open
- Jun 15, 2027 Application deadline in 321 days
- Apr 1, 2028 Award announced
- Apr 1, 2028 Project start
Program description
The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to submit samples to NIH INCLUDE Project-supported resources to generate a large volume of integrated genomic and multi-omics data that will facilitate discovery of the molecular mechanisms of health conditions related to Down syndrome. The resulting data, and associated clinical and phenotypic data, will become part of the INCLUDE Data Hub for sharing with the research community. No funding will be provided directly to applicants under this NOFO. Applicants are encouraged to propose omics assays of existing biospecimens collected from individuals with Down syndrome and controls.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- Notice of Funding Opportunity (NOFO) and application forms (specific forms to be confirmed in full NOFO)
- Biospecimen collection description and availability documentation
- Proposed omics assays and methodology
- Clinical and phenotypic data documentation
Program contact
- 👤 The INCLUDE Project
- 📧 DownSyndromeINCLUDE@mail.nih.gov
- 📞 Please contact via e-mail.
Funding track record
No recent recipient data available for CFDA 93.T21 in our database.
This can happen for newer programs, programs that use non-standard award types (loans, direct payments, fellowships), or those funded through sub-agencies under different codes.
FAQ
Can I apply for funding to collect new biospecimens?
No. This NOFO solicits samples from existing biospecimen collections only. You must already have collected samples from individuals with Down syndrome and controls.
What types of omics assays are supported?
The NOFO encourages proposals for genomic and multi-omics assays. Specific assay types may vary; check the full NOFO for details.
Will I receive direct funding?
No direct funding is provided to applicants. The goal is to submit samples and data to the INCLUDE Data Hub.
What happens to the data I submit?
All data and associated clinical/phenotypic information become part of the INCLUDE Data Hub for sharing with the research community.
When is the deadline?
The deadline is June 15, 2027. This is a fixed deadline, not rolling.
💡 Tips for applicants
- Clearly describe your existing biospecimen collection and confirm you have Down syndrome and control samples available.
- Explain how your proposed omics assays will help identify molecular mechanisms of health conditions related to Down syndrome.
- Provide complete clinical and phenotypic data to accompany your samples for the INCLUDE Data Hub.
- Review the full NOFO to understand data standards and submission requirements before preparing your application.
- Document the quality, storage conditions, and chain of custody for your biospecimens in detail.
⚠️ Common mistakes
Applications requesting direct funding or proposing new biospecimen collection will be rejected. Incomplete or poorly characterized phenotypic data reduces the value of submissions to the INCLUDE Data Hub. Applicants without existing biospecimen collections should not apply.
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