Implementation Science to End the HIV Epidemic
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 15, 2026
Can you apply?
This grant is for organizations conducting implementation science research to address HIV prevention and treatment. Eligible applicants include nonprofits, academic institutions, research organizations, and tribal entities. The grant supports research that tests and scales evidence-based interventions across diverse populations. Geographic focus varies by specific program announcement, but typically emphasizes high-burden and underserved communities.
Applicants must have institutional capacity to conduct rigorous research. Organizations must demonstrate ability to work with community partners and populations most affected by HIV. A fiscal sponsor or host institution may be required for smaller organizations.
This is a research grant, so strong scientific methodology and preliminary data are essential. Budget ranges vary by program type. Applications are typically reviewed competitively on scientific merit and impact potential.
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Key dates
- Nov 18, 2025 Applications open
- Apr 17, 2026 Application deadline
- Dec 1, 2026 Award announced
- Dec 1, 2026 Project start
Program description
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission by continuing support for implementation science to end the HIV epidemic. Projects will leverage research-community collaborations to bring evidence-based advances in HIV prevention, diagnosis, treatment, and cluster outbreak response to communities disproportionately impacted by HIV. The goals of these projects will be to: (1) Develop strategies to end HIV by integrating innovations across disciplines such as epidemiology, data science, public health, medicine, social services, implementation science, and community engagement, and (2) Deploy, test, and evaluate new or existing strategies at multiple geographic locations or settings. While deployment of these strategies will occur at the local scale, through partnerships with, local, state, and federal public health partners, the overall program will advance generalized knowledge that informs larger scale efforts to end HIV. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- County Government
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
Demographic focus
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (Application for Federal Assistance)
- SF-424 Supplement (Research and Related Other Project Information)
- Project Narrative (typically 15 pages)
- Specific Aims page
- Research Strategy section
- Budget and Budget Justification
- Biographical sketches of key personnel
- Letters of support from partners
- Human Subjects Protection documentation (if applicable)
Program contact
- 👤 Rebecca Mandt, Ph.D.
- 📧 rebecca.mandt@nih.gov
- 📞 301-435-7695
Funding track record
Recent awards under CFDA 93.855 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$246,626,852
-
$201,437,825
-
$185,816,804
-
$180,737,624
-
$136,265,880
-
$116,817,868
-
$93,394,862
-
$89,845,851
-
$74,456,241
-
$72,987,380
Top States by Funding
- CA 8 awards $696.2M
- MA 6 awards $602.8M
- NY 6 awards $335.0M
- TX 3 awards $280.9M
- GA 5 awards $257.9M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.855). How funding has trended year over year.
| 2024 | $4,073,812,529 | |
| 2025 | $4,378,235,639 | |
| 2026 est. | $4,299,426,996 |
FAQ
Who is eligible to apply?
Universities, research institutions, nonprofits, and tribal organizations can apply. Small organizations may need a fiscal sponsor or institutional partner.
What types of projects are funded?
Implementation science research that tests and scales effective HIV interventions in real-world settings. Studies with strong community engagement are preferred.
What should the project timeline be?
Most NIH research grants are 3-5 years. Specific project duration depends on the program announcement and research scope.
How competitive is this grant?
Very competitive. Success rates for NIH grants typically range 15-25%. Strong preliminary data and experienced research teams are important.
What's the typical funding range?
Budget varies by mechanism. R01-type grants are often $250K-$500K annually; other mechanisms may differ. Check the specific program announcement for details.
💡 Tips for applicants
- Target your research to high-impact populations: focus on communities most affected by HIV or facing access barriers.
- Build strong community partnerships: demonstrate authentic engagement with people with lived HIV experience or affected communities.
- Use preliminary data strategically: show pilot results or existing evidence that your approach works in your target setting.
- Follow the specific program announcement carefully: NIH has detailed instructions on page limits, budget caps, and required sections.
- Get feedback from NIH before submitting: consider a pre-submission inquiry or talk with your program officer early.
⚠️ Common mistakes
Vague implementation plans without clear metrics or sustainability strategy. Insufficient community engagement or input from affected populations. Weak preliminary data or unclear innovation compared to existing interventions.
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