Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)
🏛 Centers for Disease Control and Prevention - ERA (HHS-CDC-HHSCDCERA)
Can you apply?
This grant is for research organizations seeking to identify and evaluate risk factors for ALS. Eligible applicants include academic institutions, research universities, and nonprofit research organizations with strong epidemiological expertise. The program focuses on U.S. domestic research initiatives. Applicants must demonstrate capacity to conduct rigorous, peer-reviewed scientific research using established epidemiological methods.
This grant is for research organizations seeking to identify and evaluate risk factors for ALS. Eligible applicants include academic institutions, research universities, and nonprofit research organizations with strong epidemiological expertise. The program focuses on U.S. domestic research initiatives. Applicants must demonstrate capacity to conduct rigorous, peer-reviewed scientific research using established epidemiological methods.
Program description
CDC/ATSDR is inviting research proposals to study risk factors for Amyotrophic Lateral Sclerosis (ALS). Studies on military service, contact sports, traumatic brain injury, neuroinflammation, and infections agents and exposures are encouraged. Funding will be for four funding options: Option A – Support research with strong existing evidence such as studies on known environmental or genetic risk factors, research that improves past studies with better data, or investigations linking risk factors to ALS diagnosis and treatment; Option B – Support new and exploratory research on ALS risk factors such as studies on risk factors with little existing evidence or research using innovative methods; Option C – Understand ALS risk in affected populations, such as studies involving military veterans or investigations of ALS risk factors impacting this population; Option D – Analyze biological samples from the Guamanian ALS cluster such as investigation of disease mechanisms and environmental factors, exposure routes, genetic studies and biomarkers and how this could lead to mitigation therapeutics, diagnostics or prevention.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- County Government
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Researcher (independent)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
Details
This grant is for research organizations seeking to identify and evaluate risk factors for ALS. Eligible applicants include academic institutions, research universities, and nonprofit research organizations with strong epidemiological expertise. The program focuses on U.S. domestic research initiatives. Applicants must demonstrate capacity to conduct rigorous, peer-reviewed scientific research using established epidemiological methods.
How to apply
Application links
Required documents
- SF-424 (Application for Federal Assistance)
- Project Narrative/Scientific Proposal
- Budget and Budget Narrative
- Curriculum Vitae (all key personnel)
- Letters of Institutional Support
- Biosketches (NIH format)
Program contact
- 👤 Centers for Disease Control and Prevention - ERA
- 📧 ncipc_erpo@cdc.gov
- 📞 404-498-2015
Funding track record
Recent awards under CFDA 93.061 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$4,566,239
-
$2,860,050
-
$2,328,165
-
$2,164,528
-
$1,530,000
-
$1,500,000
-
$1,499,719
-
$1,499,585
-
$1,497,506
-
$1,441,684
Top States by Funding
- MA 3 awards $5.8M
- OH 1 awards $4.6M
- CO 2 awards $3.2M
- MI 2 awards $3.0M
- NH 2 awards $2.9M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.061). How funding has trended year over year.
| 2024 | $1,780,161 | |
| 2025 | $2,911,631 | |
| 2026 est. | $2,911,631 |
FAQ
Who can apply for this grant?
Research institutions, universities, and nonprofits with epidemiological research capacity. Individual researchers typically apply through their institutional affiliation.
What is the application deadline?
The application opens May 11, 2026 and closes June 10, 2026. This is a fixed, non-negotiable deadline.
What types of research activities are supported?
Risk factor identification and evaluation studies using epidemiological methods. Projects should focus on ALS etiology and environmental or genetic risk determinants.
How competitive is this funding?
CDC research grants are highly competitive. Demonstrated prior research productivity and novel methodologies strengthen applications.
What is the typical funding range?
CDC ERA grants vary widely. Consult the Request for Applications (RFA) for specific funding levels and project duration expectations.
💡 Tips for applicants
- Review the full RFA carefully for specific technical requirements and scientific priorities before drafting your proposal.
- Clearly articulate how your research advances understanding of ALS risk factors beyond existing literature.
- Include letters of support from collaborating institutions and experts in neurodegenerative disease research.
- Budget realistically for epidemiological study costs, including data collection and statistical analysis expertise.
- Ensure your research team includes investigators with relevant experience in ALS or neurodegenerative disease studies.
⚠️ Common mistakes
Applications lack clear connection between proposed methods and ALS risk factor identification. Budgets underestimate costs for specialized epidemiological data collection or analysis. Weak or missing evidence of institutional research infrastructure supporting the project.
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