HIV/AIDS Clinical Trials Network Laboratory Centers
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 27, 2026
Can you apply?
This grant is for institutions that conduct HIV/AIDS clinical trials research and support laboratory operations. Eligible applicants typically include university research centers, medical schools, academic medical centers, and established research institutions with NIH funding experience. The grant supports laboratory infrastructure, staffing, and operations for sites participating in the NIH's HIV/AIDS Clinical Trials Network. Applicants must demonstrate capacity to conduct rigorous clinical research and maintain accredited laboratory facilities.
Geographic scope includes all U.S. states and territories. Activities supported include laboratory operations, quality assurance, staff training, and equipment maintenance for HIV/AIDS clinical trial sites. Applicants must be prepared to participate as network members and collaborate with other participating institutions.
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Key dates
- Apr 8, 2026 Applications open
- Jan 22, 2027 Application deadline in 177 days
- Dec 1, 2027 Award announced
- Dec 1, 2027 Project start
Program description
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission by supporting four Clinical Trials Networks (CTNs) each comprised of a Leadership and Operations Center, Statistical and Data Management Center, and Laboratory Center (LC) working with Clinical Trials Units, to test prevention and treatment strategies and conduct implementation research designed to end the HIV epidemic. This NOFO will solicit applications for up to four LCs that will provide laboratory structure and technologies to one or more CTNs and conduct laboratory testing for Network trials, according to regulatory standards. The LC oversees site-affiliated clinical and specialized laboratories and ensures protocol-specified laboratory testing. The LC will: 1) support sample integrity from collection to final testing/storage; 2) use appropriate laboratory data capturing management and tracking systems; 3) select, determine readiness, and approve laboratories; and 4) promote state-of-the-art laboratory assays. The LC will increase testing capacity to meet advances in prevention and treatment of HIV and HIV-related diseases.
Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- County Government
- Hospital
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
Demographic focus
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (Federal Application for Grants)
- Project Narrative (research and operational plan)
- Budget and Budget Narrative
- Institutional Biosafety Committee approval
- Laboratory accreditation documentation
- Personnel resumes and biographies
- Letters of institutional commitment
- NIH biographical sketches
Program contact
- 👤 Division of AIDS
- 📧 sciops@niaid.nih.gov
- 📞 Please contact via e-mail.
Funding track record
Recent awards under CFDA 93.855 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$246,626,852
-
$201,437,825
-
$185,816,804
-
$180,737,624
-
$136,265,880
-
$116,817,868
-
$93,394,862
-
$89,845,851
-
$74,456,241
-
$72,987,380
Top States by Funding
- CA 8 awards $696.2M
- MA 6 awards $605.1M
- NY 6 awards $335.0M
- TX 3 awards $280.9M
- GA 5 awards $257.9M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.855). How funding has trended year over year.
| 2024 | $4,073,812,529 | |
| 2025 | $4,378,235,639 | |
| 2026 est. | $4,299,426,996 |
FAQ
Who is eligible to apply for this grant?
Academic medical centers, university research institutions, and established research organizations with HIV/AIDS clinical trial capacity. Applicants must have NIH funding experience and accredited laboratory facilities.
What does this grant fund?
Laboratory infrastructure, personnel costs, equipment, quality assurance programs, and operational expenses for HIV/AIDS clinical trial sites. It supports ongoing laboratory operations for network participation.
Is there a deadline for applications?
The application opens April 8, 2026. Check NIH's Grants.gov system or the agency website for the specific submission deadline date.
How competitive is this funding?
This is a moderately to highly competitive federal grant. Applicants need strong research records, proven laboratory management, and clinical trial experience to be competitive.
What is the typical funding range?
NIH grants for laboratory centers typically range widely. Consult the official funding announcement for specific award information and anticipated funding levels.
💡 Tips for applicants
- Emphasize your institution's HIV/AIDS research track record and prior NIH funding history in your application materials.
- Provide detailed laboratory qualifications, including accreditation status, quality assurance protocols, and biosafety certifications.
- Clearly outline your capacity and commitment to participating as an active member of the national clinical trials network.
- Detail the expertise and experience of key personnel who will manage and conduct the clinical trial work.
- Budget conservatively and justify all costs related to laboratory operations, equipment, and network participation requirements.
⚠️ Common mistakes
Underestimating laboratory operational costs or failing to account for quality assurance expenses. Submitting applications without demonstrating clear institutional commitment to clinical trial participation. Providing insufficient detail on laboratory accreditation, safety protocols, and personnel qualifications.
Similar grants
- OPEN HIV/AIDS Clinical Trials Network Leadership and Operations Centers — National Institutes of Health
- OPEN HIV/AIDS Clinical Trials Network Statistical and Data Management Centers — National Institutes of Health
- OPEN HIV/AIDS Clinical Trials Network Clinical Trials Units — National Institutes of Health
- CLOSED Infectious Diseases Clinical Trials Network (IDCTN) — National Institutes of Health
- OPEN Centers for AIDS Research (CFAR) — National Institutes of Health