Forecast to Publish a Notice of Funding Opportunity (NOFO) for NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trial Required)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 16, 2026
Can you apply?
This grant is for cancer research organizations operating at the national level. Eligible applicants are institutions with comprehensive cancer research expertise, such as cancer centers, cancer foundations, and healthcare research organizations. The UG1 requires institutional capacity for clinical trials and multi-institutional network leadership. Research must address cancer control, prevention, or care delivery through clinical research.
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Key dates
- May 28, 2025 Applications open
- Nov 14, 2025 Application deadline
- Aug 1, 2026 Award announced
- Aug 1, 2026 Project start
Program description
This Notice of Funding Opportunity (NOFO) is one of three NOFOs for the National Cancer Institute (NCI) Community Oncology Research Program (NCORP). NCORP is designed to enhance generalizability and dissemination of clinical trial results through accrual in a variety of community settings. The purpose of NCORP is to engage cancer patient populations, those at risk of cancer, and organizations in rigorous studies focused on cancer control, prevention, treatment and care delivery.
NCORP will support the following components that will be individually awarded through the respective Request for Applications (RFAs) indicated below:
- NCORP Research Bases (UG1 Clinical Trials Required);
- NCORP Community Sites (UG1 Clinical Trials Not Allowed); and
- NCORP Academic Community Sites (UG1 Clinical Trials Not Allowed)
NCORP Research Bases will serve as research hubs for the NCORP network. Research Bases are expected to:
- Provide an established organizational structure, with scientific and statistical leadership for developing, implementing, and analyzing multi-institutional cancer control, prevention, and care delivery (CCP&CD) clinical research, as well as quality-of-life studies embedded within treatment and imaging studies.
- Assume responsibility for study operations and data management, including efficient protocol development, compliance with Food and Drug Administration (FDA) and Office of Human Research Protections (OHRP) regulatory and participant protection requirements, audits, training, quality assurance, and support to Community Sites and Minority/Underserved Community Sites.
- Conduct their research activities at an institution with comprehensive expertise in cancer clinical research, such as a cancer foundation, healthcare research organization (including NCI’s National Clinical Trials Network Group Operations Centers), or NCI-designated Cancer Center.
- Integrate health disparities across all focus areas as appropriate.
The scope of research activities for the proposed NCORP Research Bases encompasses three major areas delineated below:
Area 1: Cancer Control Research; and/or
Area 2: Cancer Prevention Research; and
Area 3: Cancer Care Delivery Research.
Research Bases must cover Area 1. Areas 2 and 3 are optional.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- Institutional commitment and organizational capacity documents
- Scientific leadership qualifications and track record
- Proposed research plan addressing cancer control (required) and optional areas
- Data management and regulatory compliance procedures
- Community partner site letters of support (if applicable)
- Organizational chart showing research infrastructure
Program contact
- 👤 Brandy Heckman-Stoddard, Ph.D., M.P.H. National Cancer Institute (NCI)
- 📧 heckmanbm@mail.nih.gov
- 📞 240-276-7048
Funding track record
Recent awards under CFDA 93.399 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$22,629,848
-
$20,187,190
-
$19,625,661
-
$19,227,026
-
$18,138,327
-
$17,827,646
-
$17,614,587
-
$16,535,118
-
$16,126,587
-
$14,347,054
Top States by Funding
- NY 7 awards $57.6M
- SC 3 awards $46.6M
- DE 3 awards $43.2M
- IL 3 awards $38.4M
- WI 3 awards $37.9M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.393). How funding has trended year over year.
| 2024 | $754,945,159 | |
| 2025 | $834,514,512 | |
| 2026 est. | $520,096,276 |
FAQ
What types of institutions can apply for NCORP Research Bases?
Cancer centers, cancer foundations, healthcare research organizations, and NCI-designated Cancer Centers with established clinical trial infrastructure. Your institution must demonstrate capacity to lead multi-institutional networks.
What research areas are eligible?
Cancer control research is required. Cancer prevention and care delivery research are optional. All areas must integrate health disparities considerations.
Is this a clinical trial grant?
Yes, this specific NOFO requires UG1 clinical trial support. Other NCORP components exist for non-clinical trial community sites.
What are Research Bases responsible for?
Research Bases serve as hubs providing scientific leadership, study operations, data management, regulatory compliance, audits, training, and support to community partner sites.
When is the deadline?
The fixed deadline is November 14, 2025. This is a forecast notice; the formal NOFO will be released later with application instructions.
💡 Tips for applicants
- Position your institution as a research hub capable of supporting multiple community partner sites across cancer research networks.
- Emphasize existing infrastructure for protocol development, regulatory compliance, and data management at scale.
- Clearly address how health disparities will be integrated across your proposed research focus areas.
- Build strong preliminary data showing successful multi-institutional collaboration in cancer control or prevention research.
- Connect your proposed research to NCI's strategic priorities and existing clinical trial networks where possible.
⚠️ Common mistakes
Applying from institutions without established clinical trial infrastructure or multi-site network experience. Failing to address health disparities integration across all proposed research areas. Submitting unclear operational and data management plans for supporting community partner sites.
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