Environmental Health Sciences – Research Projects

National Institute of Environmental Health Sciences
CFDA 93.ESR Active Grant

Program Objective

The mission of the National Institute of Environmental Health Sciences (NIEHS) is to research how the environment affects biological systems across the lifespan and to translate this knowledge to reduce disease and promote health. Environmental exposures considered range from chemical, physical, and biologically derived (non-pathogenic) factors humans are exposed to through inhalation, ingestion, or ocular or dermal contact, individually or as mixtures.

Eligibility

Eligible Applicants

  • Local
  • State
  • Tribal
  • Nonprofit Organization

Eligibility criteria are outlined within the NOFO.

How to Apply

Award Procedure

Applications selected for funding undergo programmatic and policy review prior to award as described in the NOFO.

Decision Timeline

  • Approval: > 180 Days
Program details & compliance

Description

Research Projects supported by NIEHS include the development of technologies to assess human environmental exposures and the biological impacts of exposure; mechanistic understanding of exposures on biological systems including the use of environmentally derived analytes as probes of fundamental biological mechanisms; epidemiological studies of the health effects of environmental exposures including the interactions between environmental and genetic factors; community engaged research; and the identification of strategies to reduce the burden of exposure and improve human health at the individual and population levels. Studies can involve human subjects, including clinical trials, or non-human or computational model systems provided that relevance to human health is well justified.

Mission Categories

Primary: Research and Development

Other categories:
Emergency HealthGeneral Health and Medical

Required Documentation

Each applicant for research projects must present a research plan and furnish evidence that scientific competence, facilities, equipment, and supplies are appropriate to carry out the plan.
The cost
principles for awards under this program are set forth in HHS regulations at 45 CFR 75, Subpart E
and Appendix IX (hospitals) to Part 75. Commercial organizations are subject to the cost
principles located at 48 CFR 31.2 Federal Acquisition Regulation. See the NIH Grants Policy
Statement (NIH GPS) for further guidance on the applicability of cost principals
(http://grants.nih.gov/grants/policy/nihgps/index.htm).

Reporting & Compliance

Audit Required
Yes — Determined at Time of Award
Records Retention
3 years

Applicable 2 CFR 200 Subparts

  • Subpart B — General Provisions
  • Subpart C — Pre-Federal Award Requirements
  • Subpart D — Post-Federal Award Requirements
  • Subpart E — Cost Principles
  • Subpart F — Audit Requirements

Contacts

David Balshaw, Ph.D.
9842873234
530 Davis Drive, suite 3112, Morrisville, NC 27560
Data from SAM.gov Federal Assistance Listings. Source published: 2026-02-10. Spec v2.0. Last synced: 2026-05-28 07:28:38.