Oral Diseases and Disorders Research – Research Centers

NIDCR extramural research provides research funds to support basic, translational, and clinical research in dental, oral, and craniofacial health and disease through grants and cooperative agreements that support scientists working in institutions throughout the United States and internationally. The extramural Research Centers programs plan, develop, and manage scientific priorities through portfolio analyses and consultation with stakeholders, encouraging the most promising discoveries and emerging technologies for rapid translation to clinical applications. Additionally, the Centers focus on a variety of diseases and conditions through clinical trials, epidemiologic studies, practice-based research, the HIV/AIDS and oral health program, and studies of oral health in all areas of NIDCR programmatic interest. The program encourages investigations that have the potential to translate findings into evidence-based clinical applications. The Integrative Biology and Infectious Diseases programs support basic and translational research programs on oral microbiology; salivary biology and immunology; oral and salivary gland cancers; neuroscience of orofacial pain and temporomandibular disorders; mineralized tissue physiology; dental biomaterials; and tissue engineering and regenerative medicine. The branch aims to accelerate progress in basic and translational research in these areas and further stimulate the discovery pipeline based on clinical needs. The Translational Genomics Research programs support basic and translational research in genetics, genomics, developmental biology, and data science toward the goal of improving dental, oral, and craniofacial health. The focus is on deciphering the genetic, molecular, and cellular mechanisms underlying dental, oral, and craniofacial development and anomalies. The Behavioral and Social Sciences Research programs support basic and applied research to promote oral health, to prevent oral diseases and related disabilities, and to improve management of craniofacial conditions, disorders, and injury. The program prioritizes mechanistic research that contributes to a cumulative science of behavior change, to maximize the rigor, relevance, and dissemination of efficacious behavior change interventions. The Clinical Research programs supports patient-oriented, population, and community based research aimed at improving the dental, oral, and craniofacial health of the nation.

Interstate, Intrastate, State (includes District of Columbia, public institutions of higher education and hospitals), Local (includes State-designated lndian Tribes, excludes institutions of higher education and hospitals, Sponsored organization, Public nonprofit institution/organization (includes institutions of higher education and hospitals), Other public institution/organization, Federally Recognized lndian Tribal Governments, U.S. Territories and possessions, Non-Government - General, Specialized group (e.g. health professionals, students, veterans), Small business (less than 500 employees), Profit organization, Private nonprofit institution/organization (includes institutions of higher education and hospitals), Other private institutions/organizations, State, Native American Organizations (includes lndian groups, cooperatives, corporations, partnerships, associations). Research Centers: Scientists at universities, colleges, medical and dental schools, hospitals, laboratories, and other public or private nonprofit and for-profit institutions.

All accepted grant applications competing for research centers grant awards are reviewed by two advisory groups. Primary review is conducted by an initial review group composed of extramural peer scientists, and secondary review by the National Advisory Dental and Craniofacial Research Council (NADCRC). All applications receiving a priority score compete for available funds on the basis of scientific and technical merit and commercial potential of the proposed research, program relevance, and program balance among the areas of research.