Oral Diseases and Disorders Research -Research Projects

Dental, Oral and Craniofacial Research
CFDA 93.DE1 Active Grant

Program Funding

Annual program obligations reported to SAM.gov.

Latest annual funding (estimated)
$337.3M FY2026
$320M
FY24
$332.2M
FY25
$337.3M
FY26*
* estimated

Program Objective

NIDCR extramural research provides research funds to support basic, translational, and clinical research in dental, oral, and craniofacial (DOC) health and disease through grants and cooperative agreements. The extramural Research Projects programs plan, develop, and manage scientific priorities through portfolio analyses and consultation with stakeholders, to facilitate the most promising discoveries and emerging technologies for rapid translation to clinical applications for improving the health of all people across their lifespan. The extramural research programs support a broad portfolio of basic, translational, and clinical research across DOC sciences. These programs encompass oral microbiology, including HIV/AIDS; head and neck cancers; orofacial pain and temporomandibular joint disorders; dental, oral, and craniofacial mineralization and developmental anomalies. The portfolio also includes preclinical and translational research to advance precision medicine, computational and data science, regenerative medicine and tissue engineering, and the development of biomaterials and devices and immunomodulatory oral science, with the goal of accelerating translation, regulatory readiness, and clinical adoption of DOC-specific innovations. In addition, NIDCR supports patient-oriented, population, and community-based research aimed at improving the DOC health across the nation. This includes biomedical and behavioral clinical trials, research on salivary gland and rheumatic diseases, DOC health and epidemiology, and studies of fundamental biological processes.

Eligibility

Eligible Applicants

  • Nonprofit Organization
  • Not-for-Profit Organization
  • For-Profit Organization

Interstate, Intrastate, State (includes District of Columbia, public institutions of higher education and hospitals), Local (includes State-designated lndian Tribes, excludes institutions of higher education and hospitals, Sponsored organization, Public nonprofit institution/organization (includes institutions of higher education and hospitals), Other public institution/organization, Federally Recognized lndian Tribal Governments, U.S. Territories and possessions, Non-Government - General, Specialized group (e.g. health professionals, students, veterans), Small business (less than 500 employees), Profit organization, Private nonprofit institution/organization (includes institutions of higher education and hospitals), Other private institutions/organizations, State, Native American Organizations (includes lndian groups, cooperatives, corporations, partnerships, associations).

Research Project Grants: Scientists at universities, colleges, medical and dental schools, hospitals, laboratories, and other public or private nonprofit and for-profit institutions.

How to Apply

Award Procedure

All accepted grant applications competing for research project grants are reviewed by two advisory groups. Primary review is conducted by an initial review group composed of extramural peer scientists, and secondary review by the National Advisory Dental and Craniofacial Research Council (NADCRC). All applications receiving a priority score compete for available funds on the basis of scientific and technical merit and commercial potential of the proposed research, program relevance, and program balance among the areas of research.

Decision Timeline

  • Approval: > 180 Days
  • Renewal interval: > 180 Days
  • Appeal: From 90 to 120 days

All accepted grant applications competing for Other Research grants are reviewed by two advisory groups. Primary review is conducted by an initial review group composed of extramural peer scientists, and secondary review by the National Advisory Dental and Craniofacial Research Council (NADCRC). All applications receiving a priority score compete for available funds on the basis of scientific and technical merit and commercial potential of the proposed research, program relevance, and program
balance among the areas of research.

Program details & compliance

Description

The mission of the National Institute of Dental and Craniofacial Research (NIDCR) is to advance fundamental knowledge about dental, oral, and craniofacial (DOC) health and disease and translate these findings into prevention, early detection, and treatment strategies that improve overall health for all individuals and communities across the lifespan.

Mission Categories

Primary: General Health and Medical

Other categories:
Research and DevelopmentDental EducationMedical EducationBiology

Use of Funds

Allowed Uses

Health/Medical, Science and Technology
Research Project Grants and Cooperative Agreements: provide funds for salaries, equipment, supplies, travel, and other expenses associated with scientific investigation in the dental, oral and craniofacial health sciences. They are awarded to universities, colleges, medical and dental schools, hospitals, and other nonprofit and for-profit institutions. Awards include investigator-initiated project grants, exploratory and developmental grants and small grants.

Restrictions

As per requirements and restrictions described in NOFO.

Reporting & Compliance

Audit Required
Yes — Random
Records Retention
3 years

Applicable 2 CFR 200 Subparts

  • Subpart B — General Provisions
  • Subpart C — Pre-Federal Award Requirements
  • Subpart D — Post-Federal Award Requirements
  • Subpart E — Cost Principles
  • Subpart F — Audit Requirements

Contacts

Sanoj Suneja
3014027710
31 CENTER DRIVE, Bethesda, MD 20892
Gabriel Hidalgo
3018274630
31 Center Drive, Bethesda, MD 20892
Data from SAM.gov Federal Assistance Listings. Source published: 2026-02-18. Spec v2.0. Last synced: 2026-05-28 07:26:57.