Environmental influences on Child Health Outcomes (ECHO) Program

ECHO
CFDA 93.ECH Active Grant

Program Funding

Annual program obligations reported to SAM.gov.

Latest annual funding (estimated)
$174.2M FY2026
$174.2M
FY24
$174.2M
FY25
$174.2M
FY26*
* estimated

Funded Projects

Examples of what this program has supported.

FY2025 In 2025, the ECHO Program continued to build on a foundation of coordination and collaboration—demonstrating how a cohesive consortium fuels steady progress toward understanding the many factors that influence child health. Through its focus on early environmental influences—from family support and nutrition to physical and chemical exposures—ECHO advances knowledge that can enhance the lives of children today and across generations.

Program Objective

The Environmental influences on Child Health Outcomes (ECHO) Program, a nationwide research initiative, aims to investigate the root causes of childhood chronic diseases and how to prevent them. The mission is to enhance the health of children for generations to come. The Program has two major components: the ECHO Cohort for observational research and the ECHO Institutional Development Awards (IDeA) States Pediatric Clinical Trials Network (ISPCTN) for intervention research. The ECHO Cohort is the largest longitudinal child health study in the United States, with data from more than 150,000 children and their families—from before conception through age 21 years-- integrated into one powerful resource. The studies share standardized protocol, data elements, and biospecimen collection procedure managed by centralized cores.

The ECHO Institutional Development Award (IDeA) States Pediatric Clinical Trials Network (ISPCTN) brings state-of-the-art clinical trials to children and families in rural or underserved areas, focusing on conditions that disproportionately affect these communities. This network also provides capacity building and professional development to institutions in states with historically low rates of NIH funding.

The ECHO program focuses on five key pediatric outcomes that have a high public health impact: prenatal, perinatal, and postnatal outcomes; upper and lower airway conditions; obesity; neurodevelopment; and positive child health or well-being.

Eligibility

Eligible Applicants

  • Unrestricted by Entity Type

Awards can be made to domestic, public or private, for-profit or nonprofit organization, university, college, hospital, laboratory, or other institution, including State and local units of government, and individuals. Additional details on eligibility are specified in each Funding Opportunity Announcement.

How to Apply

Award Procedure

Applications are reviewed for scientific and technical merit by a scientific review group and for program relevance by a national advisory council/board.

Decision Timeline

  • Renewal interval: > 180 Days
Program details & compliance

Description

The Environmental influences on Child Health Outcomes (ECHO) Program is a research program supported by the National Institutes of Health (NIH), to enhance the health of children for generations to come. The goal of the ECHO Program is to understand the effects of a broad range of early environmental influences on child health and development. ECHO is dedicated to both learning what factors affect child health and to finding ways to enhance it. Part of what makes ECHO unique is that its structure enables investigators to conduct both observational and intervention research. These two types of research within the ECHO Program allow researchers the chance to learn through observation and through testing changes that may enhance child health.

Mission Categories

Primary: General Health and Medical

Other categories:
Maternity, Infants, Children

Use of Funds

Allowed Uses

To support research and other projects that will accelerate fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments.

Restrictions

The funding may be used to support research activities as described in the funding announcement.

Required Documentation

Applications must be submitted in compliance with instructions provided with each funding announcement.

Reporting & Compliance

Records Retention
3 years

Applicable 2 CFR 200 Subparts

  • Subpart B — General Provisions
  • Subpart C — Pre-Federal Award Requirements
  • Subpart D — Post-Federal Award Requirements
  • Subpart E — Cost Principles
  • Subpart F — Audit Requirements

Contacts

Shirley Sonia Arteaga
301-435-1033
11545 Rockville Pike, Rockville, MD 20852
Leslie C. Thompson
301-435-5239
11545 Rockville Pike, Rockville, MD 20852
Data from SAM.gov Federal Assistance Listings. Source published: 2026-01-28. Spec v2.0. Last synced: 2026-05-29 05:41:06.