Cancer Centers Support Grants

Cancer Centers
CFDA 93.397 Active Grant Cooperative Agreement

Program Funding

Annual program obligations reported to SAM.gov.

Latest annual funding (estimated)
$338.7M FY2026
$608.1M
FY24
$607.1M
FY25
$338.7M
FY26*
* estimated

Who has received this funding

Organizations awarded under CFDA 93.397 (USAspending.gov).

Funded Projects

Examples of what this program has supported.

FY2025 FY2025 funded 225 total centers.
FY2026 will fund 190 total centers.

Program Objective

To provide an organizational focus and stimulus for the highest quality cancer research that effectively promotes interdisciplinary cancer research aimed toward the ultimate goal of reducing cancer incidence, mortality and morbidity. The Cancer Center Support Grant (CCSG) provides the resources and infrastructure to facilitate the coordination of interdisciplinary programs across a broad spectrum of research from basic laboratory research to clinical investigation to population science. The CCSG supports salaries for scientific leadership of the Center, shared resources for funded center investigators, certain administrative costs, planning and evaluation, and developmental funds for new recruitments and feasibility studies.

Eligibility

Eligible Applicants

  • Local
  • State
  • Territorial
  • Tribal
  • Nonprofit Organization
  • Not-for-Profit Organization
  • For-Profit Organization
  • Small Business Person

Any nonprofit institution within the United States with a peer-reviewed cancer research base of 4.0 million dollars in direct costs may apply for a Cancer Center Support Grant.

How to Apply

Award Procedure

Grant applications are evaluated by scientific authorities for scientific and technical merit. Applications must also be reviewed by the National Cancer Advisory Board. All competitive applications compete for available funds on the basis of scientific and technical merit, program relevance, and program balance, consistent with NCI and NIH priorities and strategic plans. Initial award provides funds for the first budget period (usually 12 months) and Notice of Grant Award (Form PHS 1533-2) indicates support recommended for the remainder of the project period, allocation of Federal funds by budget categories, and special conditions, if any.

Core Grants: Approximately 10 months.

Program details & compliance

Description

To provide an organizational focus and stimulus for the highest quality cancer research that effectively promotes interdisciplinary cancer research aimed toward the ultimate goal of reducing cancer incidence, mortality and morbidity. The Cancer Center Support Grant (CCSG) provides the resources and infrastructure to facilitate the coordination of interdisciplinary programs across a broad spectrum of research from basic laboratory research to clinical investigation to population science. The CCSG supports salaries for scientific leadership of the Center, shared resources for funded center investigators, certain administrative costs, planning and evaluation, and developmental funds for new recruitments and feasibility studies.

Mission Categories

Primary: General Health and Medical

Other categories:
Research and DevelopmentHigher EducationGeneral and Special Interest OrganizationsBiology

Use of Funds

Allowed Uses

In general, CCSGs do not support research projects directly but are used to enhance the ongoing cancer research and to strengthen the existing research base according to the "Policies and Guidelines Relating to the Cancer Center Support Grant."

Required Documentation

The application requests documentation concerning the qualifications of the principal investigators and associates, pertinent budget information and justification for the support of this proposed grant. Methods to be utilized are outlined in the application materials. Costs will be determined in accordance with HHS Regulations 45 CFR, Part 75.

Reporting & Compliance

Audit Required
Yes — Annual
Records Retention
3 years

Applicable 2 CFR 200 Subparts

  • Subpart B — General Provisions
  • Subpart C — Pre-Federal Award Requirements
  • Subpart D — Post-Federal Award Requirements
  • Subpart E — Cost Principles
  • Subpart F — Audit Requirements

Contacts

Scott Chen, PhD
240-276-6038
9609 Medical Center Drive, Rockville, MD 20850
Paul Gallourakis
240-276-6437
9609 Medical Center Drive, Rockville, MD 20850
Data from SAM.gov Federal Assistance Listings. Source published: 2026-02-09. Spec v2.0. Last synced: 2026-05-28 07:28:59.