Advancing Global Health
🏛 Bureau of Global Health Security and Diplomacy
Can you apply?
This grant is for organizations working on global health priorities aligned with the America First Global Health Strategy. The Department of State invites eligible applicants to implement projects that complement bilateral MOUs and fill identified health system gaps. Specific eligibility criteria and fundable activities are detailed in APS instructions and posted Addenda. Geographic focus varies by project; applicants must align with embassy priorities and State Department health objectives. Individual addenda will specify which organization types, sectors, and geographies are eligible for particular funding opportunities.
Program description
The Department of State invites eligible applicants to advance the America First Global Health Strategy, which aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U.S. investments benefit American safety, strength, and prosperity. This Annual Program Statement (APS) establishes a supplemental framework through which the Department of State may identify and support projects that complement, extend, and/or fill identified gaps in the implementation of these bilateral MOUs. Through specific Addenda, the Department will signal priorities and needs. This APS provides the standard application instructions for the submission of all Statements of Interest (SOIs) to these specific Addenda. GHSD will collaborate with Embassies and other Department of State Bureaus and Offices to post specific funding opportunities through Addenda to this APS that address health challenges and priorities of importance.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- Statement of Interest (SOI) per Addendum instructions
- Organizational capacity documentation
- Project narrative aligned to America First Global Health Strategy
- Budget and budget narrative
- Evidence of embassy or State Department engagement (where applicable)
Program contact
- 👤 Bureau of Global Health Security and Diplomacy
- 📞 771-204-0446
Funding track record
Recent awards under CFDA 19.029 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$260,479,713
-
$188,156,394
-
$150,000,000
-
$75,278,121
-
$38,339,677
-
$589,000
-
$250,000
-
$187,000
-
$180,000
-
$160,000
Top States by Funding
- MD 1 awards $188.2M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 19.029). How funding has trended year over year.
| 2018 | $4,298,067 | |
| 2019 est. | $220,272 | |
| 2021 est. | $1,481,249 |
FAQ
Who can apply for this grant?
Eligible applicants vary by specific Addendum posted to the APS. Check the APS instructions and each Addendum for detailed eligibility criteria. Different opportunities may target NGOs, universities, or other entities.
What is the application deadline?
The fixed deadline is February 14, 2027. Submit Statements of Interest according to instructions in the specific Addendum you are applying to.
What projects are funded?
Projects must advance the America First Global Health Strategy priorities. Funded work includes strengthening health systems, improving efficiency, fostering self-reliance, and enhancing U.S. safety and prosperity outcomes.
How much can we request?
Awards range from $500,000 to $250,000,000. Exact funding levels depend on project scope and the specific Addendum priorities.
Is there cost-sharing required?
No cost-sharing is required for this grant. Applicants do not need to provide matching funds.
💡 Tips for applicants
- Review the specific Addenda posted to the APS carefully. Each Addendum signals different priorities, geographic focuses, and eligible applicant types.
- Align your project narrative directly to the America First Global Health Strategy pillars: saving lives, strengthening systems, efficiency, self-reliance, and U.S. benefit.
- Engage with the relevant embassy or State Department office early. Understanding local health priorities increases alignment and competitiveness.
- Use a Statement of Interest (SOI) format that clearly connects your organization's capacity to the identified health gaps and bilateral MOU objectives.
- Budget realistically for global health implementation. Large award ranges mean proposals must justify scope and demonstrate cost-effectiveness at any funding level.
⚠️ Common mistakes
Proposals that don't reference the specific Addendum priorities or fail to demonstrate alignment with bilateral MOUs get rejected. Weak capacity documentation for international health implementation undermines competitiveness. Vague theory of change or unclear links between activities and the America First strategy priorities are common red flags.
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