Strengthening Global Health Security by improving public health capacity to detect, notify, and respond to disease outbreaks globally
Can you apply?
This grant is for organizations strengthening global public health capacity to detect and respond to disease outbreaks. Eligible applicants typically include U.S.-based nonprofits, research institutions, universities, and public health agencies. Work must occur in low- and middle-income countries or regions with documented health security gaps. Priority activities include surveillance system strengthening, outbreak detection, rapid response capabilities, and workforce training. Geographic focus varies by funding cycle but emphasizes underserved regions with limited laboratory and epidemiological capacity.
Key dates
- Aug 22, 2025 Applications open
- Jun 25, 2026 Application deadline in 24 days
- Aug 31, 2026 Award announced
- Sep 30, 2026 Project start
This grant is for organizations strengthening global public health capacity to detect and respond to disease outbreaks. Eligible applicants typically include U.S.-based nonprofits, research institutions, universities, and public health agencies. Work must occur in low- and middle-income countries or regions with documented health security gaps. Priority activities include surveillance system strengthening, outbreak detection, rapid response capabilities, and workforce training. Geographic focus varies by funding cycle but emphasizes underserved regions with limited laboratory and epidemiological capacity.
Program description
This Notice of Funding Opportunity (NOFO) seeks to build upon activities funded by CDC to support Global Health Security (GHS) through implementation of programs and activities that focus on protecting and improving health globally through partnerships with Ministries of Health and other governmental institutions. This NOFO will build on lessons learned from the global COVID outbreak and other significant public health events. After ten years of implementing and strengthening global health security systems, the U.S. Government (USG) will continue to advance strategies to prevent, detect, and respond to public health threats. This NOFO’s main outcomes are to: 1) Improve prevention of avoidable epidemics including naturally occurring outbreaks and intentional or accidental releases of dangerous pathogens; 2) Improve ability to rapidly detect threats early, including detecting characterizing, and reporting emerging biological threats; 3) Responding rapidly and effectively to public health threats of international concern.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- County Government
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
Details
This grant is for organizations strengthening global public health capacity to detect and respond to disease outbreaks. Eligible applicants typically include U.S.-based nonprofits, research institutions, universities, and public health agencies. Work must occur in low- and middle-income countries or regions with documented health security gaps. Priority activities include surveillance system strengthening, outbreak detection, rapid response capabilities, and workforce training. Geographic focus varies by funding cycle but emphasizes underserved regions with limited laboratory and epidemiological capacity.
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 Application Form
- Project Narrative (detailed description of activities and outcomes)
- Budget and Budget Justification
- Organizational Capacity Statement
- Letters of Support from Partner Organizations
- Logic Model or Program Design
- Evaluation Plan with Performance Metrics
Program contact
- 👤 Broderick Yoerg
- 📧 DGHPNOFOs@cdc.gov
- 📞 404.234.0666
Funding track record
Recent awards under CFDA 93.318 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$77,588,113
-
$54,816,169
-
$36,307,501
-
$29,208,608
-
$28,751,856
-
$26,707,836
-
$25,214,479
-
$24,026,702
-
$23,514,463
-
$22,698,862
Top States by Funding
- DC 7 awards $81.4M
- MD 4 awards $62.9M
- NC 3 awards $52.4M
- GA 3 awards $51.0M
- VA 3 awards $32.7M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.318). How funding has trended year over year.
| 2024 | $200,769,088 | |
| 2025 | $202,608,088 | |
| 2026 est. | $234,746,685 |
FAQ
Who can apply for this grant?
U.S.-based nonprofits, universities, research institutions, and government agencies typically qualify. Organizations must demonstrate capacity to work internationally on health security projects.
What activities does this grant support?
Disease surveillance systems, outbreak detection infrastructure, laboratory capacity building, epidemiologist training, and rapid response protocols. Work focuses on low- and middle-income countries.
How competitive is this funding?
Very competitive. CDC global health grants attract strong applications from established organizations with prior international experience. First-time applicants should highlight relevant partnerships or track record.
What is the typical funding range?
Funding varies widely depending on project scope and implementation period. Award amounts typically range based on scope: planning grants smaller; full implementation larger.
When is the deadline?
Application deadline not yet specified. Monitor CDC's funding opportunity announcements and Grants.gov regularly for updates.
💡 Tips for applicants
- Emphasize measurable outcomes: specify number of laboratories upgraded, health workers trained, or cases detected early. CDC values data-driven results.
- Build partnerships with in-country ministries of health or local organizations. Collaborators strengthen both feasibility and sustainability.
- Propose realistic timelines and budgets. CDC scrutinizes cost-effectiveness on global health grants.
- Address sustainability beyond the grant period. Show how systems will continue operating after funding ends.
- Use CDC resources and frameworks. Reference WHO guidelines, CDC-supported surveillance tools, or existing health security standards in your design.
⚠️ Common mistakes
Applications fail when organizations lack demonstrated international experience or proven capacity to work in low-resource settings. Weak sustainability plans and unclear metrics for success are frequent rejections. Vague or overly ambitious scope without realistic budgets or timelines undermines competitiveness.
Similar grants
- OPEN 27-0343-10 FFY27 Local Agency General Non-Enforcement — Illinois Department of Transportation
- ROLLING Annual Agency Threshold Application Applicants for Funding Start Here — Texas City of Austin - Austin Public Health
- CLOSED Virginia’s Black Indigenous and People of Color (BIPOC) Grant – FY26 — Virginia The Virginia Department of Historic Resources
- ROLLING RTAP Grant Program (Rolling) — Virginia Department of Rail and Public Transportation
- ROLLING Rail Industrial Access Grant (RIA) — Virginia Department of Rail and Public Transportation