Advancing Global Health
🏛 Bureau of Global Health Security and Diplomacy
Can you apply?
This grant is for organizations advancing global health security, disease prevention, and health system strengthening in bilateral partnership countries. Eligible applicants typically include U.S. government agencies, nonprofits, universities, and implementing partners with international health expertise. Activities supported include disease surveillance, capacity building, health workforce development, and infrastructure improvements. All work must align with bilateral MOUs and America First Global Health Strategy priorities signaled through specific Addenda.
This grant is for organizations advancing global health security, disease prevention, and health system strengthening in bilateral partnership countries. Eligible applicants typically include U.S. government agencies, nonprofits, universities, and implementing partners with international health expertise. Activities supported include disease surveillance, capacity building, health workforce development, and infrastructure improvements. All work must align with bilateral MOUs and America First Global Health Strategy priorities signaled through specific Addenda.
Program description
The Department of State invites eligible applicants to advance the America First Global Health Strategy, which aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U.S. investments benefit American safety, strength, and prosperity. This Annual Program Statement (APS) establishes a supplemental framework through which the Department of State may identify and support projects that complement, extend, and/or fill identified gaps in the implementation of these bilateral MOUs. Through specific Addenda, the Department will signal priorities and needs. This APS provides the standard application instructions for the submission of all Statements of Interest (SOIs) to these specific Addenda. GHSD will collaborate with Embassies and other Department of State Bureaus and Offices to post specific funding opportunities through Addenda to this APS that address health challenges and priorities of importance.
Who can apply
Eligible applicants
Details
This grant is for organizations advancing global health security, disease prevention, and health system strengthening in bilateral partnership countries. Eligible applicants typically include U.S. government agencies, nonprofits, universities, and implementing partners with international health expertise. Activities supported include disease surveillance, capacity building, health workforce development, and infrastructure improvements. All work must align with bilateral MOUs and America First Global Health Strategy priorities signaled through specific Addenda.
How to apply
Application links
Key dates & requirements
Required documents
- Statement of Interest (SOI) as specified in APS
- Project narrative aligned to relevant Addendum
- Detailed budget and budget narrative
- Evidence of bilateral MOUs or partnerships
- Organizational capacity documentation
- Compliance certifications (per State Department requirements)
Program contact
- 👤 Bureau of Global Health Security and Diplomacy
- 📞 771-204-0446
Funding track record
Recent awards under CFDA 19.029 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$260,479,713
-
$188,156,394
-
$150,000,000
-
$75,278,121
-
$38,339,677
-
$589,000
-
$250,000
-
$187,000
-
$180,000
-
$160,000
Top States by Funding
- MD 1 awards $188.2M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
FAQ
Who can apply for this grant?
The APS instructions define eligibility. Typically U.S. nonprofits, universities, and implementing partners with international health experience are eligible. Check specific Addenda for organization-type restrictions.
What is the application deadline?
The fixed deadline is February 14, 2027. Specific Addenda may have different submission windows, so monitor program announcements closely.
What types of projects are funded?
Projects addressing health priorities in partner countries, including disease control, health systems strengthening, surveillance, and capacity building aligned with bilateral MOUs.
How competitive is this funding?
Very competitive. Awards range from $500K to $250M across the $2.1B funding pool. Strong international partnerships and alignment with State Department priorities are essential.
Do I need to provide matching funds?
No cost sharing is required for this grant.
💡 Tips for applicants
- Review specific Addenda first. This APS establishes the framework, but priorities and requirements vary by Addenda—read each carefully.
- Demonstrate bilateral partnership. Strong MOUs and local government support are critical to competitiveness and program success.
- Align with America First Global Health Strategy. Show how your project saves lives, strengthens systems, and benefits U.S. interests.
- Build in sustainability. Funders expect projects to foster self-reliance and lasting health system improvements in partner countries.
- Start early on compliance. State Department grants involve extensive compliance documentation—allow significant time for APS instructions review.
⚠️ Common mistakes
Proposals failing to align with bilateral MOUs or the America First Global Health Strategy priorities. Weak demonstration of how the project fosters partner-country self-reliance and sustainability. Insufficient emphasis on U.S. benefits, safety, and strategic interests alongside global health impact.
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