GREGoRi Technology Integration Center (U01, Clinical Trials Optional)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 15, 2026
Can you apply?
This grant is for research institutions seeking to establish or enhance technology integration capabilities in geriatric and gerontologic research. Eligible applicants include academic medical centers, research universities, and nonprofit research institutions with strong clinical research infrastructure. The program focuses on supporting research centers that will serve as hubs for clinical trials and technology innovation in aging-related studies. Geographic scope is national. Funded institutions must commit to conducting or supporting geriatric clinical research and providing technical resources to the research community.
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Key dates
- Jun 18, 2026 Applications open
- Jul 6, 2026 Award announced
- Jul 6, 2026 Project start
- Oct 30, 2026 Application deadline in 106 days
Program description
The National Human Genome Research Institute (NHGRI) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to renew the Genomics Research to Elucidate the Genetics of Rare Disease (GREGoR) program. The renewal, called GREGoR: Innovation (GREGoRi), seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this NOFO is to establish the GREGoRi Technology Integration Center (TechIC), which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis.
This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in 2025 with an expected application due date in 2026. This NOFO will utilize the U01 activity code.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- County Government
- Private University
- Public Authority
- Public K-12 School
- Public University
- Small Business (SBA-defined)
- State Government
- Tribal Nation
- Tribal Organization
Demographic focus
How to apply
Application links
Key dates & requirements
Required documents
- PHS 398 Research Plan (with specific sections for center goals and technology infrastructure)
- Budget and Budget Justification
- Institutional Commitment Letter
- Letters of Support from collaborating institutions
- C.V.s of key personnel
- Description of existing research infrastructure
- Letters of Intent (if required for the specific announcement)
Program contact
- 👤 Lisa H. Chadwick National Human Genome Research Institute (NHGRI)
- 📧 lisa.chadwick@nih.gov
- 📞 301-435-7275
Funding track record
Recent awards under CFDA 93.172 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$39,531,110
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$34,574,245
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$32,186,204
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$30,195,606
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$26,495,937
-
$26,020,371
-
$24,964,130
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$24,413,854
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$23,757,911
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$22,977,417
Top States by Funding
- CA 19 awards $317.2M
- MA 16 awards $302.5M
- WA 9 awards $140.1M
- NY 6 awards $93.6M
- NC 5 awards $93.0M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.172). How funding has trended year over year.
| 2024 | $452,727,668 | |
| 2025 | $423,878,429 | |
| 2026 est. | $9,989,158 |
FAQ
Who is eligible to apply for this grant?
Academic medical centers, research universities, and established nonprofit research institutions are typically eligible. Organizations must have existing research infrastructure and capacity to establish a technology integration center.
What types of projects are funded?
This grant supports creation or enhancement of technology integration centers focused on geriatric and gerontologic research, including clinical trials infrastructure and technology platforms.
Is this grant competitive?
Yes. U01 mechanisms are highly competitive NIH awards. Strong preliminary data, institutional commitment, and a clear research vision are essential.
What is the typical funding range?
U01 awards typically range from $500,000 to several million dollars annually, though exact amounts vary by institute and competition.
When is the application due?
Check the NIH grants.gov page or the relevant NIH Institute/Center website for current submission deadlines, as they vary by funding opportunity announcement.
💡 Tips for applicants
- Emphasize your institution's existing geriatric research capacity and clinical infrastructure. Reviewers want to see institutional commitment.
- Develop a clear sustainability plan showing how the center will remain viable beyond the grant period.
- Include specific, measurable goals for how your technology platform will serve the broader research community.
- Build strong collaborative partnerships with other research institutions or clinical sites to demonstrate network value.
- Address how your center will support clinical trials and provide accessible resources to investigators nationwide.
⚠️ Common mistakes
Underestimating the institutional commitment required and lacking clear evidence of long-term sustainability. Failing to demonstrate how the center will serve a broader research community beyond your institution. Submitting weak preliminary data or unclear technical specifications for the proposed technology platform.
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