Priority HIV/AIDS Research within the Mission of NIDDK (R01 Clinical Trial Optional)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Sep 4, 2026
Can you apply?
This grant is for researchers conducting HIV/AIDS studies within NIDDK's research mission. Eligible applicants include doctoral-level researchers at universities, medical centers, and research institutes. Applicants must have institutional affiliation and appropriate credentials in biomedical research. The grant supports U.S. domestic research projects addressing HIV/AIDS topics aligned with NIDDK priorities. Funding focuses on clinical research with optional clinical trial components.
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Program description
This Notice of Funding Opportunity (NOFO) seeks to stimulate HIV/AIDS research within the mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) that align with the HIV/AIDS research priorities outlined by the NIH Office of AIDS Research (OAR). These priorities were most recently described in NOT-OD-20-018 UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- County Government
- Hospital
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Researcher (independent)
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
Demographic focus
How to apply
Application links
Required documents
- SF-424 (R&R) form
- Project Narrative (Research Strategy)
- Detailed Budget and Budget Justification
- Biographical Sketch (2 pages)
- Bibliography/References
- Human Subjects Protection documentation (if applicable)
- Vertebrate Animal Care documentation (if applicable)
- Institutional support letters
- Letters of collaboration
Program contact
- 👤 National Institutes of Health
- 📧 grantsinfo@nih.gov
- 📞 301-402-2541
Funding track record
Recent awards under CFDA 93.847 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$438,527,853
-
$200,221,259
-
$152,979,352
-
$112,529,392
-
$82,457,560
-
$48,585,892
-
$45,186,589
-
$37,490,770
-
$34,242,949
-
$32,783,433
Top States by Funding
- WA 4 awards $513.7M
- NC 4 awards $291.6M
- NY 5 awards $184.3M
- FL 2 awards $184.1M
- PA 6 awards $176.9M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.847). How funding has trended year over year.
| 2024 | $1,971,472,000 | |
| 2025 | $2,043,166,000 | |
| 2026 est. | $111,289,000 |
FAQ
Who can apply for this grant?
Researchers with doctoral degrees affiliated with research institutions. This includes scientists at universities, medical centers, and independent research organizations with institutional support.
What is the application deadline?
The deadline is fixed at November 5, 2027. Applications open January 8, 2025. Plan ahead for internal institutional reviews and approvals.
What types of research does this grant support?
HIV/AIDS research within NIDDK's mission areas. Clinical research is prioritized, with optional clinical trial components. Review NIDDK's current research priorities before applying.
How competitive is this funding?
NIH R01 grants are highly competitive. Success rates typically range 15-20%. Strong preliminary data and experienced research teams significantly improve competitiveness.
What is the typical funding range?
R01 grants vary widely by field and project scope. Budget requests typically range $200,000 to $500,000 annually. Check with your institution's research office for current guidelines.
💡 Tips for applicants
- Start with a strong research question grounded in preliminary data. Reviewers expect feasibility demonstrated by pilot studies or published results.
- Build a clear connection to NIDDK's stated research priorities. Read recent funding announcements and program announcements to align your aims.
- Provide detailed methodology and realistic timelines for each specific aim. Vague methods or overambitious scope raises reviewer concerns about feasibility.
- Include letters of support from collaborators and institutional commitment from research administrators. This demonstrates institutional backing for your project.
- Submit early through your institution's grants office. NIH submissions have hard deadlines; system delays can result in rejection without review.
⚠️ Common mistakes
Applying without clear alignment to NIDDK's specific research focus areas. Reviewers reject applications when HIV/AIDS work doesn't fit stated program priorities.
Presenting insufficient preliminary data or pilot results. Strong R01 applications demonstrate feasibility through existing research evidence.
Underestimating the scope or setting unrealistic timelines. Overly ambitious projects with weak methodology plans receive poor feasibility scores.
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