OPEN CFDA 93.172 ↗ Competitive Cooperative Agreement Competitive ~100h typical effort

Genomic Community Resources (U24 Clinical Trials Not Allowed)

🏛 National Institutes of Health (HHS-NIH11)

✓ Free, no account · Source: Grants.gov · Last verified Jul 16, 2026

⏰ Deadline
Jan 25, 2027 in 192 days
📊 Total program funding
$30M
🎯 Expected awards
6 recipients
📅 Fiscal Year
FY 2027
📍 Scope
National

Can you apply?

This grant is for institutions and organizations that develop, maintain, or distribute genomic research resources and tools for the scientific community. Eligible applicants include research institutions, universities, hospitals, and nonprofit research organizations with research capabilities. The program supports infrastructure projects that serve multiple investigators across institutions. Activities include creating databases, establishing tissue repositories, developing bioinformatics platforms, and providing training in genomic methods.

The project must benefit a broad research community and not focus on a single investigator's clinical work. International collaboration is permitted when it strengthens U.S. research capacity. This mechanism prioritizes sustainability and long-term impact on the genomics research landscape.

Eligible applicants
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Key dates

  1. Feb 9, 2026 Applications open
  2. Jan 25, 2027 Application deadline in 192 days
  3. Dec 1, 2027 Award announced
  4. Dec 1, 2027 Project start

Program description

The National Human Genome Research Institute (NHGRI), with other NIH Institutes and Centers (ICs) National Cancer Institute (NCI) and National Institute of Environmental Health Sciences (NIEHS), intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications to facilitate genomic research and the dissemination of its products, NHGRI proposes this RFA to support both new and existing genomic resources of demonstrated broad value to the research community. Awards under this NOFO will support the development, curation, and distribution of high-value genomic resources valuable for both basic and clinical genomics research. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.  This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of genomic resource development are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in computational genomics and data science and clinical applications of genomics will be encouraged and these investigators should also begin considering applying for this application. 

Who can apply

Eligible applicants

How to apply

Application links

Key dates & requirements

  • 📅 Expected award date: Dec 1, 2027
  • 🚀 Project start date: Dec 1, 2027

Required documents

  • SF-424 (R&R)
  • Project Narrative (specific aims, significance, innovation, approach)
  • Budget and Budget Narrative
  • Biographical Sketches (NIH Format)
  • Resources and Environment
  • Letters of Support (from anticipated users and collaborators)
  • Data Management and Sharing Plan
  • Facilities and Equipment

Program contact

Funding track record

Recent awards under CFDA 93.172 from the last 3 years — real organizations that won funding through this same program.

83
awards (3 yrs)
$1.4B
total funded
43
unique recipients
$16.3M
average award

Top 10 Largest Recent Awards

  1. $39,531,110
  2. $34,574,245
  3. $32,186,204
  4. $30,195,606
  5. $26,495,937
  6. $26,020,371
  7. $24,964,130
  8. $24,413,854
  9. $23,757,911
  10. $22,977,417

Top States by Funding

  • CA 19 awards $317.2M
  • MA 16 awards $302.5M
  • WA 9 awards $140.1M
  • NY 6 awards $93.6M
  • NC 5 awards $93.0M

Source: USAspending.gov — federal spending transparency. Data covers last 3 years.

Funding history

Annual funding for this program — Federal obligations (CFDA 93.172). How funding has trended year over year.

2024 $452,727,668
2025 $423,878,429
2026 est. $9,989,158

FAQ

What types of institutions can apply?

Research universities, medical centers, nonprofit research organizations, and government laboratories. Your institution must have research infrastructure and organizational capacity to support a resource program.

Can my application include a clinical trial?

No. This program explicitly does not support clinical trials. Focus on tool development, database creation, or resource provision instead.

What counts as a genomic resource?

Databases, tissue/sample repositories, software platforms, bioinformatics tools, and training programs that serve multiple research groups beyond your institution.

How competitive is this grant?

NIH research infrastructure grants are moderately to highly competitive. Strong applications demonstrate clear community need and long-term sustainability plans.

What is the typical funding level?

U24 grants typically range from $250,000 to $600,000 per year. Actual amounts vary based on project scope and agency priorities.

💡 Tips for applicants

  • Show clear community demand. Provide letters of support from researchers who will use your resource.
  • Develop a realistic sustainability plan. Explain how the resource will remain accessible after grant funding ends.
  • Demonstrate technical expertise. Include CVs and publications from your team in relevant genomics areas.
  • Define measurable outputs. Specify how many users, datasets, or tools your resource will produce annually.
  • Align with NIH priorities. Reference relevant NHGRI or NCCBI strategic plans and ongoing genomics initiatives.

⚠️ Common mistakes

Proposing a resource with uncertain long-term sustainability or unclear path to user adoption. Treating the resource as primarily benefiting your institution rather than serving a broad, external research community.

Similar grants

Source: Grants.gov · FY 2027 · Last updated May 27, 2026

192 days left Jan 25, 2027
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