Limited Competition: NIMHD Initiative for Improving American Indian and Alaska Native Cancer Outcomes (U19 – Clinical Trial Optional)
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 16, 2026
Can you apply?
This grant is for research institutions and organizations working to improve cancer prevention, diagnosis, and treatment in American Indian and Alaska Native communities. Eligible applicants typically include universities, medical centers, tribal organizations, and research institutions with capacity to conduct cancer research. This is a limited competition grant, so only selected eligible organizations can apply. The research must address cancer outcomes in AI/AN populations, particularly in rural areas.
Projects can focus on cancer prevention, early detection, treatment, or policy approaches affecting AI/AN cancer care. Multi-disciplinary teams and partnerships with tribal communities are strongly encouraged.
Applicants should have research infrastructure and experience working with AI/AN populations. Organizations must demonstrate cultural competency and meaningful tribal engagement in project design.
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Key dates
- Jul 16, 2026 Applications open
- Jan 25, 2027 Application deadline in 192 days
- Sep 30, 2027 Award announced
- Sep 30, 2027 Project start
Program description
The purpose of this Notice of Funding Opportunity (NOFO) is to support research that addresses the prevention, diagnosis, and treatment of cancers among American Indians and Alaska Natives (AI/AN), particularly those living in rural communities. The research objectives target overall cancer incidence and mortality, with the goal of making findings applicable and impactful in improving cancer outcomes in AI/AN patients and their families.
This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
Who can apply
Eligible applicants
Demographic focus
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (R&R) application form
- Project Narrative
- Budget and Budget Justification
- Biographical sketches of key personnel
- Letters of institutional commitment
- Letters of support from tribal organizations
- Data management plan (if applicable)
Program contact
- 👤 NIMHD DCHPS Scientific Team
- 📧 NIMHDDCHPSScientificTeam@mail.nih.gov
- 📞 Please contact via e-mail
Funding track record
Recent awards under CFDA 93.307 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$57,145,935
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$48,558,256
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$45,796,667
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$43,100,665
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$41,194,375
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$38,870,836
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$37,991,760
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$37,142,240
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$35,966,257
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$35,161,090
Top States by Funding
- CA 9 awards $245.6M
- NC 4 awards $112.1M
- TX 5 awards $93.2M
- NY 6 awards $91.5M
- GA 3 awards $76.6M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
FAQ
Who can apply for this grant?
This is a limited competition. Only eligible organizations invited by NIH can apply. Universities, research institutions, and tribal organizations with cancer research capacity typically qualify.
What is the deadline?
The deadline is January 25, 2027. This is a fixed deadline, not rolling.
What types of research are supported?
Cancer prevention, diagnosis, treatment, and health outcomes research focused on AI/AN populations. Rural health approaches and policy research are eligible.
How competitive is this funding?
Highly competitive. Only meritorious applications are funded. Strong preliminary data and tribal partnerships improve competitiveness.
What is the funding range?
The total pool is $3 million. Individual award amounts are not specified. Awards typically range from $250,000 to $500,000 annually for U19 cooperative agreements.
💡 Tips for applicants
- Prioritize meaningful partnership with tribal communities in project design. Tribal advisory boards strengthen applications.
- Clearly connect your proposed research to reducing cancer disparities in AI/AN populations.
- Address how findings will be disseminated and used by AI/AN communities, not just published.
- Include a dedicated cultural competency and health equity section in your proposal.
- Demonstrate existing relationships and trust with AI/AN populations through past work and letters of support.
⚠️ Common mistakes
Weak tribal partnerships or community engagement plans. Applications treating AI/AN populations as research subjects rather than co-investigators and leaders. Unclear connection between research activities and AI/AN cancer outcome improvement.
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