Kidney Precision Medicine Project Recruitment Sites (U01 Clinical Trial Not Allowed)
Can you apply?
This grant is for research institutions and medical centers to serve as recruitment and clinical assessment sites for a kidney precision medicine study. Eligible applicants include academic medical centers, hospitals, and research organizations with capacity to enroll diverse patient cohorts with kidney disease.
The grant supports patient recruitment, screening, baseline assessments, and specimen collection. Applicants must demonstrate access to underrepresented populations and commitment to enrollment diversity. Sites must have IRB approval and clinical infrastructure in place.
This is a research-focused opportunity requiring existing clinical programs serving kidney disease patients. Geographic scope is national. No clinical trial testing new therapeutics is permitted under this mechanism.
Key dates
- Jun 3, 2026 Applications open
- Jul 10, 2026 Application deadline in 27 days
- Jun 1, 2027 Award announced
- Jul 1, 2027 Project start
Program description
This Notice of Funding Opportunity (NOFO) requests applications for the Kidney Precision Medicine Project (KPMP) – Recruitment Sites (RS) to enroll participants with either acute kidney injury (AKI) and/or chronic kidney disease (CKD) into a longitudinal cohort study and perform protocol-based research kidney biopsies. The RS will collaborate with the Tissue Interrogation Sites (TIS), Kidney Tissue Atlas Coordinating Center (KTACC), and Central Hub (CH) to obtain and evaluate kidney biopsies from participants, create a Kidney Tissue Atlas, define disease subgroups, and identify critical cells, interstitial components, pathways, and targets for novel therapies.
Who can apply
Eligible applicants
- 501(c)(3) Public Charity
- City / Municipal Government
- County Government
- Hospital
- Nonprofits
- Private University
- Public Authority
- Public K-12 School
- Public University
- Small Business (SBA-defined)
- Special District
- State Government
- Tribal Nation
- Tribal Organization
Demographic focus
How to apply
Application links
Key dates & requirements
Required documents
- R&R SF-424 Form (research & related)
- Project Narrative (Specific Aims, Significance, Innovation, Approach)
- Budget and Budget Justification
- Biosketch for key personnel (PD/PI and co-investigators)
- Letters of support from institution and collaborating clinicians
- Recruitment and Retention Plan
- IRB Approval Letter
Program contact
- 👤 Debbie S. Gipson, MS, MD
- 📧 Debbie.Gipson@nih.gov
- 📞 301-480-2268
Funding track record
Recent awards under CFDA 93.847 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$152,979,352
-
$112,529,392
-
$66,521,567
-
$45,186,589
-
$37,867,943
-
$37,490,770
-
$34,242,949
-
$31,624,784
-
$31,124,496
-
$31,065,476
Top States by Funding
- FL 2 awards $184.1M
- MA 6 awards $165.7M
- PA 6 awards $165.0M
- NY 4 awards $143.8M
- MD 2 awards $143.4M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.847). How funding has trended year over year.
| 2024 | $1,971,472,000 | |
| 2025 | $2,043,166,000 | |
| 2026 est. | $111,289,000 |
FAQ
What organizations can apply?
Academic medical centers, hospitals, and established research institutions with kidney disease patient populations. Organizations must have IRB approval and clinical research infrastructure.
What activities does this grant fund?
Patient recruitment, clinical assessment, baseline data collection, and biospecimen collection for the precision medicine study. Compensation for participant visits and data management are eligible.
Can this fund a clinical trial of a new treatment?
No. Clinical trials testing new therapeutics are explicitly not allowed under this mechanism. This is recruitment and assessment only.
Who will be most competitive?
Sites with diverse patient populations, prior recruitment experience, and strong community connections. Demonstrated commitment to health equity strengthens applications.
What's the typical funding range?
Most NIH U01 sites receive $150,000–$400,000+ annually, but varies by enrollment targets and site responsibilities.
💡 Tips for applicants
- Highlight your institution's reach to underrepresented and socioeconomically diverse kidney disease populations.
- Show existing clinical programs and patient registries that support recruitment goals.
- Detail your community partnerships and patient engagement strategies in the recruitment plan.
- Include letters of support from collaborating clinicians and community health worker networks.
- Explain how you'll ensure data quality and timeliness of specimen/data submissions to the coordinating center.
⚠️ Common mistakes
Missing diversity and enrollment strategy. Weak or vague recruitment plans without evidence of reach to underrepresented groups. Understaffing and lack of dedicated research coordinator or data manager role.
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