DoW Pancreatic Cancer Research Program, Translational Research Partnership Award
Can you apply?
This grant is for partnerships of at least two principal investigators conducting pancreatic cancer research. Research institutions (universities, medical centers, nonprofits) with established cancer research programs can apply.
The partnership must include at least one member with expertise in pancreatic cancer research or clinical care. Projects must address at least one of the FY26 PCARP Focus Areas.
Applications can support pilot studies, retrospective analyses, and correlative studies. Large-scale clinical trials are not eligible. Preliminary data supporting the research hypothesis is required but does not need to be from pancreatic cancer studies.
Program description
Summary: The fiscal year 2026 (FY26) Pancreatic Cancer Research Program (PCARP) Translational Research Partnership Award supports partnerships between clinicians, population scientists, applied scientists and/or basic scientists that will accelerate the movement of promising ideas in pancreatic cancer toward clinical applications. The partnership must include at least one member with expertise in pancreatic cancer research or pancreatic cancer patient care. All applications must address at least one of the FY26 PCARP Focus Areas.
· This award mechanism requires preliminary data to support feasibility of the research hypothesis(es) and research approaches. However, these data do not necessarily need to originate from studies of pancreatic cancer. Applications can support retrospective tissue analysis, correlative studies and pilot clinical trials; however, this mechanism does not allow large-scale clinical trials.
· The Translational Research Partnership Award requires two Principal Investigators (PIs) referred to as the Initiating PI and the Partnering PI. Only the Initiating PI will submit a pre-application, but both PIs will need to submit at the full application stage. The partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- Pre-application (Initiating PI only)
- SF-424 (R&R)
- Project Narrative
- Budget and Budget Justification
- Biosketches (both PIs)
- Letters of Support
- Preliminary Data/Supporting Materials
Program contact
- 👤 Jamie Shortall Grant Officer
- 📧 help@eBRAP.org
- 📞 301-619-2393
Funding track record
Recent awards under CFDA 12.420 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$2,265,729,366
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$800,631,761
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$74,531,880
-
$67,205,571
-
$53,718,832
-
$34,191,124
-
$24,907,742
-
$21,394,379
-
$19,100,256
-
$19,002,641
Top States by Funding
- MD 10 awards $3,150.1M
- NC 11 awards $132.3M
- FL 8 awards $99.8M
- CA 11 awards $99.3M
- MA 7 awards $75.2M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 12.420). How funding has trended year over year.
| 2024 | $1,483,968,520 | |
| 2025 | $1,201,153,417 |
FAQ
Who can serve as Principal Investigators for this award?
You must have two PIs: an Initiating PI and a Partnering PI. Both must have strong expertise relevant to the project, and at least one must specialize in pancreatic cancer research or patient care.
Can I submit a single-PI application?
No. This award specifically requires a two-PI partnership structure. Both will submit applications at the full stage.
What types of research activities are supported?
Pilot clinical trials, retrospective tissue analysis, and correlative studies are eligible. Large-scale clinical trials are not supported by this mechanism.
What preliminary data do I need?
You need preliminary data supporting your research hypothesis and approach. This data can come from studies of other cancers, not necessarily pancreatic cancer.
Is there cost-sharing required?
No cost-sharing is required for this award.
💡 Tips for applicants
- Build a true partnership with complementary expertise. Clearly define each PI's distinct scientific role and contributions.
- Identify which FY26 PCARP Focus Area your project addresses early. Your entire application strategy should align with that area.
- Gather strong preliminary data even if it comes from non-pancreatic cancer research. Focus on demonstrating feasibility of your approach.
- Plan the Initiating PI's pre-application carefully. Rejection or withdrawal of the pre-application means both full applications can be withdrawn.
- Ensure your Partnering PI's abbreviated application clearly shows their distinct portion of the work and their cancer expertise.
⚠️ Common mistakes
Failing to clearly define complementary roles and distinct contributions for each PI. Submitting without addressing an FY26 PCARP Focus Area. Proposing a large-scale clinical trial instead of a pilot or translational study.
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