Controlling and Preventing STIs in US Health Departments (CAP-STIs)
🏛 Centers for Disease Control - NCHHSTP
Can you apply?
This grant is for public health departments to strengthen STI prevention and control services. State, local, territorial, and tribal health departments are eligible to apply. Activities include surveillance, testing, treatment, partner notification, and health promotion in clinical and community settings. This is a CDC cooperative agreement focused on preventing sexually transmitted infections across the United States.
Applicants must be established health departments with capacity to implement evidence-based STI services. Federal employees and contractors may have restrictions. Non-U.S. entities are generally not eligible. Priority may be given to departments serving high-burden STI populations.
Key dates
- May 11, 2026 Applications open
- Aug 29, 2026 Application deadline in 89 days
- Feb 1, 2027 Award announced
- Feb 1, 2027 Project start
This grant is for public health departments to strengthen STI prevention and control services. State, local, territorial, and tribal health departments are eligible to apply. Activities include surveillance, testing, treatment, partner notification, and health promotion in clinical and community settings. This is a CDC cooperative agreement focused on preventing sexually transmitted infections across the United States.
Applicants must be established health departments with capacity to implement evidence-based STI services. Federal employees and contractors may have restrictions. Non-U.S. entities are generally not eligible. Priority may be given to departments serving high-burden STI populations.
Program description
CDC is funding programs that track, prevent, and control sexually transmitted infections (STI) in state, district, territorial, and city or county health departments.
The purpose of this NOFO is to track, prevent, and control three common STIs: syphilis, gonorrhea, and chlamydia.
The NOFO supports the goals of the Sexually Transmitted Infections National Strategic Plan 2021-2025:
- Prevent new STIs.
- Improve the health of people by reducing adverse outcomes of STIs.
- Implement STI prevention technology and innovations more quickly.
- Reduce the impact of STIs in areas or populations disproportionately impacted by STIs.
- Achieve integrated, coordinated efforts that address the STI epidemic.
Local surveillance data will determine the priority populations for this NOFO. Each program should focus on populations that are disproportionately impacted by STI transmission.
To be successful with this NOFO, you will need to collaborate with partners to address interconnected comorbidities and sexual health.
Who can apply
Eligible applicants
- City / Municipal Government
- County Government
- Public K-12 School
- Special District
- State Government
- Tribal Nation
Demographic focus
Details
This grant is for public health departments to strengthen STI prevention and control services. State, local, territorial, and tribal health departments are eligible to apply. Activities include surveillance, testing, treatment, partner notification, and health promotion in clinical and community settings. This is a CDC cooperative agreement focused on preventing sexually transmitted infections across the United States.
Applicants must be established health departments with capacity to implement evidence-based STI services. Federal employees and contractors may have restrictions. Non-U.S. entities are generally not eligible. Priority may be given to departments serving high-burden STI populations.
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (Application for Federal Assistance)
- Project Narrative and Work Plan
- Budget and Budget Narrative
- Organizational Capacity Statement
- Letters of Support from Partners
- CDC Form for Assurances and Compliance
Program contact
- 👤 Puja Seth
- 📧 idj5@cdc.gov
- 📞 (404) 639-6334
Funding track record
Recent awards under CFDA 93.977 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$3,392,957,048
-
$1,643,859,160
-
$1,304,575,254
-
$1,167,031,150
-
$1,164,965,484
-
$1,007,746,374
-
$790,994,189
-
$699,268,753
-
$668,709,667
-
$640,126,315
Top States by Funding
- CA 9 awards $4,971.8M
- NY 4 awards $1,754.2M
- MD 5 awards $1,310.9M
- NC 3 awards $1,224.7M
- MI 3 awards $1,223.6M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.977). How funding has trended year over year.
| 2024 | $126,507,929 | |
| 2025 | $117,841,318 | |
| 2026 est. | $117,841,318 |
FAQ
Who is eligible to apply for CAP-STIs?
State, local, territorial, and tribal health departments. Federal employees typically cannot apply as individuals.
What activities does this grant support?
STI surveillance, testing, treatment, partner services, health promotion, and data systems. Clinical and community-based interventions are included.
What is the typical funding amount?
Awards vary by jurisdiction and capacity. Typically ranges from $100,000 to $500,000+ annually for cooperative agreements.
How competitive is this grant?
Very competitive. CDC STI grants attract applications from most eligible health departments nationally.
When is the application due?
Specific deadline dates vary by funding cycle. Check Grants.gov for exact deadlines when the funding announcement opens.
💡 Tips for applicants
- Align your application with CDC's current STI prevention priorities. Review recent strategic plans and data on local burden.
- Demonstrate existing STI program infrastructure and qualified staff. Reviewers assess organizational readiness and capacity.
- Include specific, measurable targets for testing, treatment, and disease prevention outcomes. Data-driven goals are critical.
- Partner with local clinics, community organizations, and labs. Document collaborations and memoranda of understanding.
- Address health equity explicitly. Show how your plan serves disproportionately affected populations and reduces STI disparities.
⚠️ Common mistakes
Applications lack specific epidemiologic data on local STI burden. Applicants propose generic activities instead of tailored interventions. Weak partnerships or collaboration documentation undermine capacity assessments.
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