Clinical and Translational Science Award
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 20, 2026
Can you apply?
This grant is for academic medical centers and research institutions conducting clinical and translational science. Eligible applicants must be organizations capable of establishing a CTSA Hub with integrated research and training infrastructure. Institutions must demonstrate capacity for moving scientific discoveries into clinical practice and community health implementation.
The award supports creation of a national network providing infrastructure, expertise, and collaboration across the translational research spectrum. Funded institutions coordinate clinical research, develop and disseminate research methods and technologies, and provide training in clinical and translational science. Geographic scope is national.
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Key dates
- Jul 20, 2026 Applications open
- Jan 25, 2027 Application deadline in 187 days
- Dec 15, 2027 Award announced
- Dec 15, 2027 Project start
Program description
The purpose of the Congressionally mandated Clinical and Translational Science Award (CTSA) Program is to accelerate the translation of scientific discoveries into treatments, diagnostics, and health interventions that improve patient and public health by funding and coordinating a national network of academic medical centers that provide the infrastructure, expertise, training, and collaboration needed to move discoveries from the laboratory into clinical practice and community health. The purpose of the reissuance of the CTSA Notice of Funding Opportunity (NOFO) is to support a CTSA Hub that provides an integrated research and training environment for clinical and translational science and catalyzes the development, demonstration, and dissemination of methods and technologies that dramatically improve efficiency and quality across the translational research spectrum.
Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
This is a Forecast that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (R&R) form
- Project Narrative/Research Strategy
- Budget and Budget Justification
- Institutional biosketches for key personnel
- Organizational capacity documentation
- Letters of institutional commitment
Program contact
- 👤 Division of Clinical Innovation, NCATS
- 📧 CTSANOFOQuestions@mail.nih.gov
- 📞 Please contact via email.
Funding track record
Recent awards under CFDA 93.350 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$139,753,636
-
$118,592,298
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$118,098,707
-
$112,138,469
-
$102,903,347
-
$102,422,256
-
$100,095,982
-
$99,978,264
-
$98,955,036
-
$97,784,066
Top States by Funding
- CA 13 awards $652.0M
- NY 11 awards $506.1M
- MA 6 awards $321.4M
- NC 5 awards $313.7M
- OH 5 awards $162.0M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.350). How funding has trended year over year.
| 2024 | $595,597,945 | |
| 2025 | $626,227,752 |
FAQ
Who is eligible to apply for a CTSA Hub award?
Academic medical centers and research institutions with capacity to build integrated clinical and translational science infrastructure. Your organization must be able to coordinate a regional research network.
Is this a one-time award or can it be renewed?
CTSA Hubs typically receive multi-year funding with renewal opportunities. Awards support sustained networks and long-term infrastructure development.
What activities does the CTSA support?
Infrastructure development, research training, methods development, technology dissemination, and coordination of clinical and translational research across institutions.
When is the application deadline?
The fixed deadline is January 25, 2027. Typically applications open 4-6 weeks before the deadline.
What budget categories are allowed?
Salaries, equipment, facilities, training stipends, and indirect costs are typically allowable. Consult the full NOFO for detailed budget guidance.
💡 Tips for applicants
- Start by reviewing the full NOFO carefully. The reissued notice may have new requirements or structural changes from previous CTSA cycles.
- Emphasize your institution's existing clinical and translational research capacity. Reviewers assess your baseline infrastructure and partnerships.
- Develop a clear strategic plan showing how your Hub will serve your region and contribute to the national network goals.
- Engage collaborating institutions early. Strong inter-institutional partnerships are critical for a competitive Hub application.
- Budget generously for infrastructure and coordination staff. CTSA Hubs require dedicated personnel to manage the network.
⚠️ Common mistakes
Applications lack clear focus on translational research mission. Weak institutional partnerships or unclear regional network structure. Insufficient detail on infrastructure, training programs, or methods dissemination plans.
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