Nursing Research – SBIR-STTR

CFDA 93.NR4 Active Grant

Program Funding

Annual program obligations reported to SAM.gov.

Latest annual funding (estimated)
$6.3M FY2026
$5.7M
FY24
$6.3M
FY25
$6.3M
FY26*
* estimated

Funded Projects

Examples of what this program has supported.

FY2025 11 Research Grants
FY2026 11 Research Grants

Program Objective

Nurses understand that improving health and well-being means addressing people’s needs in multiple settings, contexts, and over the life course. NINR-supported science uses nursing’s holistic patient and community-focused perspective and wide reach across clinical and community settings to improve individual and population health by addressing the conditions where people live, learn, work, and play: those factors that are at the root of the health challenges that we see. NINR has a longstanding and continued commitment to developing the next generation of nurse scientists: those individuals and teams who will carry nursing research into the future.

Eligibility

Eligible Applicants

  • U.S. Federal Government
  • U.S. State Government
  • U.S. Territory Government
  • Department/Agency of U.S. State
  • Federally Recognized Tribal Government
  • Tribally Designated Housing Authority
  • Municipality/Township Government
  • County Government
  • Local Government Consortium
  • Public Housing Authority
  • Foreign Nonprofit Organization
  • Foreign Not-for-Profit Organization
  • Foreign For-Profit Organization
  • International Organization
  • Nonprofit Organization
  • Not-for-Profit Organization
  • For-Profit Organization

SBIR grants can be awarded only to domestic small businesses (entities that are independently owned and operated for profit and have no more than 500 employees). Primary employment (more than one-half time) of the principal investigator must be with the small business at the time of award and during the conduct of the proposed project. STTR grants can be awarded only to domestic small business concerns (entities that are independently owned and operated for profit and have no more than 500 employees) which "partner" with a non-profit research institution to conduct cooperative research and development. Under the SBIR program, for both Phase I and Phase II, the primary employment of the PD/PI must be with the small business concern at the time of award and during the conduct of the proposed project.

How to Apply

Award Procedure

Each application receives a dual scientific review by non-NIH scientists. Awards are issued by the National Institute of Nursing Research (NINR). All accepted applications are evaluated for scientific and technical merit by an appropriate scientific peer review panel and by a national advisory council. All applications deemed competitive compete for available SBIR/STTR set-aside funds on the basis of scientific and technical merit and the commercial potential of the proposed research, program relevance, and program balance among the areas of research.

Decision Timeline

  • Approval: From 120 to 180 days
  • Renewal interval: > 180 Days
Program details & compliance

Description

Small business program (SBIR and STTR) grants include the following activity codes: R41, R42, R43, R44.

Mission Categories

Primary: General Health and Medical

Use of Funds

Allowed Uses

Grantee agrees to administer the grant in accordance with the regulations and policies governing the research grant programs of the Public Health Service as stated in the terms and conditions on the application for the grant. SBIR Phase I grants (of approximately 6-months' duration) are to establish the technical merit and feasibility of a proposed research effort that may lead to a commercial product or process. Phase II grants are for the continuation of the research initiated in Phase I and which are likely to result in commercial products or processes. STTR Phase I grants (normally of 1-year duration) are to determine the scientific, technical, and commercial merit and feasibility of the proposed cooperative effort that has potential for commercial application.

Required Documentation

Applicants should submit electronically via Grants.gov as directed in the relevant NIH Funding Opportunity Announcement. All required forms specified in the application kit are to be completed by the applicant and submitted with the application package. For-profit organizations' costs are determined in accordance with 48 CFR, Subpart 31.2 of the Federal Acquisition Regulations. For other grantees, costs will be determined by HHS Regulations, 45 CFR, Part 74, Subpart Q. 2 CFR 200, Subpart E - Cost Principles applies to this program.

Reporting & Compliance

Audit Required
Yes — Not Required
Records Retention
3 years

Applicable 2 CFR 200 Subparts

  • Subpart B — General Provisions
  • Subpart C — Pre-Federal Award Requirements
  • Subpart D — Post-Federal Award Requirements
  • Subpart E — Cost Principles
  • Subpart F — Audit Requirements

Contacts

Elizabeth Tarlov, Director, Division of Extramural Science Programs — Chief, Office of Extramural Programs
3015945989
31 Center Drive, Bethesda, MD 20892
Data from SAM.gov Federal Assistance Listings. Source published: 2026-02-03. Spec v2.0. Last synced: 2026-05-29 05:37:16.